A5100413198- Acute Ischemic Stroke Management
- Lipoproteins and Cardiovascular Health
- Pancreatitis Pathology and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Cardiac Imaging and Diagnostics
- Kawasaki Disease and Coronary Complications
- Surgical Sutures and Adhesives
- Drug Transport and Resistance Mechanisms
- Gallbladder and Bile Duct Disorders
- Cerebrovascular and Carotid Artery Diseases
- Pediatric Hepatobiliary Diseases and Treatments
- Inflammasome and immune disorders
- Blood Coagulation and Thrombosis Mechanisms
- Body Contouring and Surgery
- Cardiac Arrhythmias and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- IgG4-Related and Inflammatory Diseases
- Electrospun Nanofibers in Biomedical Applications
- Atherosclerosis and Cardiovascular Diseases
- COVID-19 Clinical Research Studies
- Autoimmune and Inflammatory Disorders Research
- Hemostasis and retained surgical items
- Gastrointestinal disorders and treatments
- Radiomics and Machine Learning in Medical Imaging
- Thyroid Disorders and Treatments
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Dalian Medical University
2022-2023
Chongqing Medical University
2022-2023
Second Affiliated Hospital of Chongqing Medical University
2022-2023
Anhui Provincial Children's Hospital
2023
Huazhong University of Science and Technology
2023
Children's Hospital of Fudan University
2022-2023
Wuhan Children's Hospital
2022-2023
Taiyuan University of Technology
2023
Background and Purpose: It is still unclear whether the residual cholesterol inflammatory risk in acute phase associated with prognosis of stroke. We aimed to investigate proportion relative contribution risk, determined by baseline low-density lipoprotein (LDL-C) high-sensitivity C-reactive protein (hsCRP) levels, recurrent stroke poor functional outcome at 1 year. Methods: In this prospective multicenter cohort study, 10 499 consecutive ischemic transient attack patients levels LDL-C hsCRP...
Abstract Autoimmune pancreatitis (AIP) is identified as a severe chronic immune‐related disorder in pancreas, including two subtypes. In this study, pancreatic lesions patients diagnosed either type 1 AIP or 2 are examined, and these patients’ peripheral blood at single‐cell level. Furthermore, flow cytometry, immunofluorescence, functional assays performed to verify the cell AIP, there notable increase amount of B cells plasma cells, IgG4+ key pathogenic AIP. The differentiation path...
The global prevalence of acute and chronic wounds has surged, escalating healthcare burdens necessitating advanced therapeutic strategies for effective wound management. Electrospun nanofibers have emerged as promising biomimetic platforms...
Acute pancreatitis is a common critical and acute gastrointestinal disease worldwide, with an increasing percentage of morbidity. However, the gene expression pattern in peripheral blood has not been fully analyzed. In addition, mechanism coronavirus 2019 (COVID-19)-induced investigated. Here, after bioinformatic analysis machine-learning methods data cells validation local patients, two functional modules were identified, S100A6, S100A9, S100A12 validated as predictors severe pancreatitis....
This study aimed to explore the feasibility of ultrasound radiomics analysis before invasive coronary angiography (ICA) for evaluating severity artery disease (CAD) quantified by SYNTAX score (SS). included 105 carotid plaques from patients (64 low-SS patients, 41 intermediate-high-SS patients). The clinical characteristics and three-dimensional (3D-US) features ICA were assessed. Ultrasound images used analysis. Least absolute shrinkage selection operator (LASSO) regression, which generated...
Background Many patients after stroke are found to have elevated serum creatine kinase (CK). This study aimed investigate the associations between CK levels and clinical outcomes in with acute ischemic or transient attack. Methods Results The included 8910 attack from CNSR‐III (Third China National Stroke Registry). Baseline admission were measured. (stroke recurrence, death, disability, defined as modified Rankin scale score 3–6 2–6) analyzed. Patients had higher risks of recurrent (hazard...
Background and Purpose: Although elevated serum lipoprotein (a) [Lp(a)] is considered to be a risk factor of ischemic stroke, the relationship between Lp(a) cognitive impairment after stroke remains unclear. This study investigated association function acute (AIS) or transient attack (TIA). Methods: The included 1,017 patients diagnosed with AIS TIA from cognition subgroup Third China National Stroke Registry (CNSR3). Montreal Cognitive Assessment (MoCA) at 2 weeks discharge, 3 months, 1...
To study the expression of interleukin-17A (IL-17A) in serum children with intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) and its clinical significance.A total 143 KD who were hospitalized Wuhan Children's Hospital, Tongji Medical College, Huazhong University Science Technology, from June 2021 to 2022 enrolled this prospective study, among whom 115 had IVIG-sensitive 28 IVIG-resistant KD. After matching for sex age, 110 acute respiratory infectious diseases (fever time ≥5...
This retrospective study aimed to observe the efficacy of transcatheter arterial chemoembolization (TACE) combined with sirolimus in treatment haemangioma Kasabach-Merritt phenomenon (KMP).A total 11 infants KMP who were treated at our hospital from January 2016 September 2021 selected and arteriosclerosis embolotherapy using a microsphere emulsion formed by bleomycin + ultra-fluid lipiodol dexamethasone contrast agent or mixed microspheres as embolising agent. The patients administered...
Abstract Polylactic acid (PLA) surgical suture is considered to be one of the most ideal materials for tissue closure due its rich raw and excellent biological properties. However, sutures face great challenges problems such as wound infection reaction in practical applications. In order improve clinical applicability sutures, we constructed a new drug-loading system core-spun sutures. The shell was composed nanofibrous membranes polyglycolic (PGA) polycaprolactone (PCL) ciprofloxacin (CIP)...
Abstract Objective: The DAMPs such as HMGB1, S100A12 and IL-17A have been reported to predict poor response IVIG. aim of this study was analyze the role HMGB1,S100A12 in detection inflammation KD patients with IVIG-resistant, investigate value different adjunctive therapy. Method: This enrolled 126 diagnosed KD, well age-matched 16 febrile control subjects. demographic or clinical data, laboratory parameter blood sample were collected. Various parameters predictive factors for IVIG-resistant...
Abstract The liver manifestations of Alagille syndrome (ALGS) are highly variable, and factors affecting its prognosis poorly understood. We asked whether or not the composition bile acids in ALGS patients with good clinical outcomes differs from those poor outcomes, could be used as prognostic biomarkers. Blood for acid profiling were collected genetically confirmed JAG1 -associated before one year age. Good was defined survival native total bilirubin (TB) < 85.5 µmol/L, while either...