Long Guo

ORCID: 0000-0002-2571-5542
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About
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Natural product bioactivities and synthesis
  • Phytochemicals and Antioxidant Activities
  • Advanced Measurement and Detection Methods
  • Essential Oils and Antimicrobial Activity
  • Metabolomics and Mass Spectrometry Studies
  • Phytochemistry and Biological Activities
  • Remote Sensing and Land Use
  • Chromatography in Natural Products
  • Phytochemical Studies and Bioactivities
  • Biometric Identification and Security
  • Image Processing Techniques and Applications
  • Ionic liquids properties and applications
  • Food Quality and Safety Studies
  • Natural Products and Biological Research
  • Bee Products Chemical Analysis
  • Phytochemical compounds biological activities
  • Advanced Algorithms and Applications
  • Traditional Chinese Medicine Studies
  • Industrial Vision Systems and Defect Detection
  • Alkaloids: synthesis and pharmacology
  • Ginseng Biological Effects and Applications
  • Plant-based Medicinal Research
  • Advanced Chemical Sensor Technologies
  • Image and Object Detection Techniques

Sichuan University
2025

Hebei University of Chinese Medicine
2018-2024

People's Liberation Army 401 Hospital
2024

Yale University
2024

Sichuan Agricultural University
2024

Hospital of Hebei Province
2024

Hebei University
2022-2023

State Administration of Traditional Chinese Medicine of the People's Republic of China
2023

Hubei University of Chinese Medicine
2023

Southwest University
2022

Deep eutectic solvents (DESs) are emerging as green and sustainable for efficient extraction of bioactive compounds or drugs. This work aimed to comprehensively evaluate the potential effectiveness DESs different types natural from biomass. Five Chinese herbal medicines including Berberidis Radix, Epimedii Folium, Notoginseng Radix et Rhizoma, Rhei Rhizoma Salviae Miltiorrhizae were selected assess efficiency on alkaloids, flavonoids, saponins, anthraquinones, phenolic acids, respectively....

10.1021/acssuschemeng.6b00091 article EN ACS Sustainable Chemistry & Engineering 2016-02-18

In the present study, a simple and environmentally friendly extraction method based on natural deep eutectic solvents (NADESs) was established to extract four bioactive steroidal saponins from Dioscoreae Nipponicae Rhizoma (DNR). A total of twenty-one types choline chloride, betaine, L-proline NADESs were tailored, NADES composed 1:1 molar ratio chloride malonic acid showed best efficiency for compared with other NADESs. Then, parameters by selected tailor-made optimized using response...

10.3390/molecules26072079 article EN cc-by Molecules 2021-04-05

Pancreatic lipase is a key for triacylglyceride digestion and absorption, which recognized as promising target treatment of metabolic disorders. Natural phytochemicals are hopeful sources pancreatic inhibitors. The leaves Artemisia argyi H.Lév. Vaniot (AL) commonly used herbal medicine or food supplement in China other Asian countries hundreds years. AL mainly contains essential oils, phenolic acids, flavonoids terpenoids, exhibit many pharmacological activities such antioxidant,...

10.3389/fphar.2021.675396 article EN cc-by Frontiers in Pharmacology 2021-05-07

10.1109/icassp49660.2025.10887657 article EN ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP) 2025-03-12

The identification of species is a crucial component the Chinese patent medicine (CPM) quality evaluation system. Nevertheless, intricate and varied chemical compositions different herbs pose persistent challenge to this study. This study proposes strategy combining high-resolution mass spectrometry with molecular networking (MN) data processing tools comprehensively characterize compounds in Yixishu lotion (YXSL) identify composition. First, collected by HPLC-Q-TOF-MS were systematically...

10.1002/bmc.70069 article EN Biomedical Chromatography 2025-04-02

Abstract Calcium carbonate (CaCO3) biomineralization is an ancient evolutionary feature of life that plays a key role in environmental adaptation. In plants, CaCO3 deposition found several taxa; however, current knowledge its formation and ecological adaptive implication limited. Here, we used the chalk gland plant Ceratostigma willmottianum to gain insight into biomineralization. We secretion crystals are mainly composed (> 90%), consists sixteen cells with four secretory pores on...

10.1093/plphys/kiaf134 article EN PLANT PHYSIOLOGY 2025-04-04

Angelica dahurica(BZ) and dahurica var. formosana(HBZ) are two plant sources of Angelicae dahuricae Radix. Although BZ HBZ commonly used herbal medicines with great medicinal dietary values, study on their phytochemicals bioactive compositions is limited.To compare the chemical find makers for discrimination quality evaluation botanical origins Radix.A high-performance liquid chromatography coupled quadrupole time-of-flight mass spectrometry method was established profiling HBZ. Then, a...

10.1002/pca.3129 article EN Phytochemical Analysis 2022-04-26

This study aimed to investigate the microbial viability, edible qualities, and flavor volatiles of enzymatically hydrolyzed 'Orah' (Citrus reticulata Blanco) puree separately using Lactobacillus paracasei JLPF-176 (LP) Bifidobacterium infantis JYBI-373 (BI) as starters during fermentation storage. The results showed that fermented citrus contains sufficient viable counts (6–8 log CFU/mL) Probiotics increased content organic acids, total phenolic (TPC), flavonoid (TFC), antioxidant...

10.1016/j.lwt.2022.114009 article EN cc-by-nc-nd LWT 2022-09-20

Citrus grandis 'Tomentosa' (CGT) is particularly cultivated in China and widely used health foods. In this study, the chemical profiles of different parts CGT were comprehensively compared by rapid resolution liquid chromatography coupled to electrospray ionization quadrupole time-of-flight mass spectrometry method. A total 22 compounds identified two C-glucosyl flavones found for first time CGT. Four main constituents (rhiofolin, naringin, meranzin hydrate, isoimperatorin) simultaneously...

10.1021/jf5036355 article EN Journal of Agricultural and Food Chemistry 2014-10-22

The Artemisia argyi leaf (AL) has been used as a traditional medicine and food supplement in China other Asian countries for hundreds of years. Phytochemical studies disclosed that AL contains various bioactive constituents. Among constituents, phenolic acids have recognized the main active compounds AL. To best our knowledge, no research focused on extraction method from Nowadays, deep eutectic solvents (DESs) are emerging new type green sustainable solvent efficient natural products. In...

10.3390/molecules24152842 article EN cc-by Molecules 2019-08-05

Raw Ephedrae herba (REH) and honey-processed (HEH) were the different decoction pieces of (EH). Honey-processing that changes REH into HEH has been shown to relieve cough asthma a synergistic extent. However, chemical markers mechanism need be further studied. In this study, ultra-high performance liquid chromatography coupled with hybrid quadrupole time flight mass spectrometry (UPLC-Q-TOF-MS) molecular networking (MN) used investigate composition HEH, which led identification 92 compounds....

10.3390/molecules27134057 article EN cc-by Molecules 2022-06-23
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