A5005485556- Advanced Fiber Laser Technologies
- Photonic Crystal and Fiber Optics
- Photoreceptor and optogenetics research
- Neuroscience and Neural Engineering
- Chinese history and philosophy
- Photonic and Optical Devices
- Optical Network Technologies
- Advanced Fiber Optic Sensors
- Advanced Sensor and Energy Harvesting Materials
- Parasitic infections in humans and animals
- Molecular Communication and Nanonetworks
- Phase-change materials and chalcogenides
- Neural dynamics and brain function
- Semiconductor Lasers and Optical Devices
- Advanced Memory and Neural Computing
- Blood Pressure and Hypertension Studies
- Toxoplasma gondii Research Studies
- Dialysis and Renal Disease Management
- Solid State Laser Technologies
- Cancer Research and Treatments
- Parasitic Infections and Diagnostics
- Electrowetting and Microfluidic Technologies
- Laser-Matter Interactions and Applications
- Medical Research and Treatments
- GaN-based semiconductor devices and materials
Tsinghua University
2017-2024
Chinese Institute for Brain Research
2020-2024
University of Electronic Science and Technology of China
2024
Dalian Medical University
2024
First Affiliated Hospital of Dalian Medical University
2024
The Sixth People's Hospital of Shenyang
2024
Zunyi Medical University
2021-2023
University of Arizona
2021-2023
Yunnan University
2023
Beijing Institute of Petrochemical Technology
2023
Broadband laser light sources in the mid-infrared region attract enormous interest due to plethora of applications they are enabling, including multispecies trace gas detection, free-space communications, and infrared countermeasures. Key progress supercontinuum generation has been wide availability fiber-based near-infrared bulk-optic pump suitably engineered nonlinear media capable supporting high-brightness supercontinua. A large proportion system complexity relates source itself with...
Significance Materials and devices that upconvert photons from low to high frequencies are of tremendous interest for broad applications in bio- chemical sensing, infrared imaging, display, photovoltaics. Here we develop self-powered, micrometer-scale optoelectronic upconversion infrared-to-visible photon upconversion. The realized microscale device exhibits a practical efficiency 1.5% under incoherent low-power illumination, with emission intensity linearly dependent on excitation. Other...
Flexible biocompatible electronic systems that leverage key materials and manufacturing techniques associated with the consumer electronics industry have potential for broad applications in biomedicine biological research. This study reports scalable approaches to technologies of this type, where thin microscale device components integrate onto flexible polymer substrates interconnected arrays provide multimodal, high performance operational capabilities as intimately coupled biointerfaces....
Abstract Physical and chemical technologies have been continuously progressing advances in neuroscience research. The development of research tools for closed-loop control monitoring neural activities behaving animals is highly desirable. In this paper, we introduce a wirelessly operated, miniaturized microprobe system optical interrogation neurochemical sensing the deep brain. Via epitaxial liftoff transfer printing, microscale light-emitting diodes (micro-LEDs) as light sources...
The standard of clinical care in many pediatric and neonatal neurocritical units involves continuous monitoring cerebral hemodynamics using hard-wired devices that physically adhere to the skin connect base stations commonly mount on an adjacent wall or stand. Risks iatrogenic injuries associated with adhesives bond such systems entanglements patients and/or healthcare professionals wires can impede procedures natural movements are critical care, development, recovery patients. This paper...
Conventional organic light-emitting devices without an encapsulation layer are susceptible to degradation when exposed air, so realization of air-stable intrinsically-stretchable display is a great challenge because the protection against penetration moisture and oxygen even more difficult under stretching. An that composed electroluminescent device (SELD) integrated with stretchable color-conversion (SCCL) contains perovskite nanocrystals (PeNCs) proposed. PeNCs normally decay but they...
Abstract Optogenetic methods provide efficient cell-specific modulations, and the ability of simultaneous neural activation inhibition in same brain region freely moving animals is highly desirable. Here we report bidirectional neuronal activity manipulation accomplished by a wireless, dual-color optogenetic probe synergy with co-expression two spectrally distinct opsins (ChrimsonR stGtACR2) rodent model. The flexible comprises vertically assembled, thin-film microscale light-emitting diodes...
Inorganic semiconductor-based microscale light-emitting diodes (micro-LEDs) have been widely considered the key solution to next-generation, ubiquitous lighting and display systems, with their efficiency, brightness, contrast, stability, dynamic response superior liquid crystal or organic-based counterparts. However, reduction of micro-LED sizes leads deteriorated device performance increased difficulties in manufacturing. Here, we report a tandem scheme based on stacked red, green, blue...
We report the first chalcogenide microwire designed with all-normal dispersion to generate supercontinuum by optical wave breaking, a low-noise nonlinear process. The (As2S3) is coated PMMA and tapered diameter of 0.58 μm achieve regime. generated spectrum spans over an octave from 960 >2500 nm using length only 3 mm low pulse energy 150 pJ.
Abstract Materials and device strategies to form inorganic, thin‐film, microscale light‐emitting diodes (micro‐LEDs) are presented based on a simplified release method. High performance gallium nitride blue micro‐LEDs fabricated released from both patterned sapphire substrates (PSSs) conventional nonpatterned (CSSs). Micro‐LEDs transferred onto copper polyimide flexible their electrical optical performances maintained. Thermal properties of PSS CSS systematically explored different...
Abstract Simultaneous neuron stimulation and biophysiological sensing in multi‐encephalic regions can lead to profound understanding of neural pathways, neurotransmitter transportation, nutrient metabolism. Here, a flexible electronic device with tentacle‐like channels radiating from central wireless circuit is presented. The constructed by different organic inorganic materials that have been made into thin‐film or nanoparticle formats. All equipped components for distributed synchronized...
We demonstrate all-fiber far-detuned and widely tunable mid-infrared wavelength conversion using As2Se3 microwires. In a first experiment, an idler is generated tuned from 2.351 to >2.500 μm four-wave mixing in 0.5 cm long microwire. second parametric sidebands are via modulation instability 10 The resulting frequency reaches up 49.3 THz, the largest ever reported soft glass materials.
Recording and interrogating brain activities using optical methods have become emerging technologies in neuroscience. Traditional tools for optogenetic stimulation the deep are mostly based on implantable fibers, imposing constraints animal movement. Recently developed microscale light-emitting diodes (micro-LEDs), which can be wirelessly operated, serve as injectable light sources that directly interact with neural systems. Here, we exploit a controlled, system studies behaving animals....
We introduce the PC- and COP-cladded As2Se3 microwires, two highly nonlinear microwires optimized to operate in wavelength range of 1.85 µm 2.20 µm. Like previously reported PMMA-cladded microwire, benefit a large waveguide parameter engineerable chromatic dispersion level, but without absorption features PMMA μm range. The design rules fabrication technique each polymer-cladded microwire is provided. COP- with identical length nonlinearity are also operated regime, highlighting self-phase...
Taenia solium ( T. ) cysticercosis is a neglected parasitic zoonosis that occurs in developing countries. Since has complex life cycle includes eggs, oncospheres, cysticerci, and adults, presumably many proteins are produced enable them to survive establish an infection within the host. The objectives of this study were perform comparative proteomic analysis two ontogenetic stages (cysticerci adult) analyze their differential expression proteins. Methods separated by High Performance Liquid...
Abstract Miniaturized, wearable, and implantable optoelectronic devices systems provide incomparable opportunities for applications in biomedical fields. Optical filters with wavelength selective reflective/transmissive responses that can be integrated onto these biointegrated platforms are critically important high performance operation. Here, quality, dielectric thin‐film optical on unconventional substrates via transfer printing reported. Designed formed flexible exhibit highly spectral...
We report the first chalcogenide-based optical parametric oscillator (OPO) relying on pure gain. The all-fiber OPO operates in wavelength range of 2 μm and is tunable over 290 nm from combined Stokes anti-Stokes contributions. gain medium a 10 cm long chalcogenide microwire made high modal confinement As2Se3 core with cyclo olefin polymer cladding, leading to optimized chromatic dispersion, nonlinearity, broadband transparency. With power threshold only fraction milliwatt, this design...
Abstract Blood pressure variability (BPV) is significantly associated with cardiovascular diseases (CVD) and mortality in hemodialysis patients. However, the relationship between blood CVD patients complex affected by many factors. The present study aimed to assess association of long‐term predialysis BPV all‐cause major adverse events (MACE). One thousand seven hundred twenty‐seven receiving maintenance were recruited nine centers. Predialysis was assessed over 1‐year intervals. Outcomes...
We demonstrate optical transmission results of highly nonlinear As2Se3 microwires cladded with fluorine-based CYTOP, and compare them typical hydrogen-based polymers. In the linear optics regime, CYTOP-cladded microwire transmits light in spectral range from 1.3 µm up to >2.5 without trace absorption peaks such as those observed using polymer claddings. The is also pumped showing multiple-orders four-wave mixing supercontinuum generation spanning 1.0 >4.3 µm. conclude that a broadband...
Using tapered fibers of As2Se3 chalcogenide glass, we produce photon pairs at telecommunication wavelengths with low pump powers. We found maximum coincidences-to-accidentals ratios $2.13\pm0.07$ for degenerate pumping 3.2 {\mu}W average power, and $1.33\pm0.03$ non-degenerate 1.0 1.5 power the two pumps. Our results show that ultrahigh nonlinearity in these microwires could allow single-photon to pairs, enabling production large entangled states, heralding single photons after lossy...
A single-frequency distributed-Bragg-reflector fiber laser at 980 nm with a quantum defect of less than 0.6% was developed 1.5-cm 12 wt% ytterbium-doped phosphate pumped by 974.5-nm diode. Linearly polarized single-longitude-mode polarization extinction ratio (PER) nearly 30 dB and spectral linewidth 1.8 kHz obtained. maximum output power 275 mW measured launched pump 620 mW. The performance the 909 976 also characterized. This research demonstrated an approach to high-power oscillators...
In this paper, we present the demonstration of a 10-W level picosecond Yb <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3+</sup> -doped master oscillator and power amplifier at 976 nm in all-fiber configuration. A linear-cavity fiber laser mode-locked by semiconductor-saturable-absorber-mirror was developed as seed with pulse width 10.9 ps operating repetition rate 34.1 MHz. The average amplified to 8.1 W two core-pumped pre-amplifiers...
Panic disorder (PD) involves emotion dysregulation, but its underlying mechanisms remain poorly understood. Previous research suggests that implicit regulation may play a central role in PD-related dysregulation and symptom maintenance. However, there is lack of studies exploring the neural PD using neurophysiological indicators.