A5027189804- Agricultural pest management studies
- Wheat and Barley Genetics and Pathology
- Plant Genetic and Mutation Studies
- Agricultural Economics and Practices
- Acute Lymphoblastic Leukemia research
- Genetics and Plant Breeding
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Insect Pest Control Strategies
- Agricultural Practices and Plant Genetics
- Botanical Research and Chemistry
- Plant Reproductive Biology
- Plant-based Medicinal Research
- Insect Resistance and Genetics
- Genetic and Environmental Crop Studies
- Crop Yield and Soil Fertility
- Rice Cultivation and Yield Improvement
- Genetically Modified Organisms Research
- Pesticide Residue Analysis and Safety
- Agricultural Science and Fertilization
- Genetic Mapping and Diversity in Plants and Animals
- Chronic Myeloid Leukemia Treatments
- DNA and Nucleic Acid Chemistry
- Eosinophilic Disorders and Syndromes
- Flowering Plant Growth and Cultivation
Tata Memorial Hospital
2005-2024
Homi Bhabha National Institute
2023-2024
Advanced Centre for Treatment, Research and Education in Cancer
2018-2023
Maharana Pratap University of Agriculture and Technology
2013-2023
Swami Keshwanand Rajasthan Agricultural University
2013-2020
Indian Institute of Management Udaipur
2019
Systems, Applications & Products in Data Processing (Canada)
2018
Indian Agricultural Research Institute
1968-2015
Central Agricultural University
2012
National Centre for Writing
2004
Abstract The use of pediatrics-inspired protocols in adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) results superior survival compared with the protocols. Pediatrics-inspired carry an increased risk toxicity treatment-related mortality low resource settings, which can offset potential benefits. We studied outcomes prognostic factors treatment AYA ALL a regimen. retrieved data regarding demographics, investigations, details, toxicities from electronic medical records...
Background: Cytogenetics is one of the most important diagnostic parameters in classification acute leukemia. Recurrent chromosomal aberrations leukemia have provided insights into molecular mechanism leukemogenesis. The variable frequencies recurrent cytogenetic markers due to ethical/racial differences been reported from Western and some Asian countries. Objective: We report data largest cohort 7209 adult pediatric patients with de novo (AL) determine prevalence various sub groups compare...
ABSTRACT Pediatric chronic myeloid leukemia (pCML) is a rare childhood malignancy, representing 2%–3% of all leukemia. Tyrosine kinase inhibitors (TKIs) have greatly improved survival but pose challenges due to their long‐term effects on growth and bone health in children. We prospectively studied treatment‐free remission (TFR) 45 children with pCML phase imatinib. Eligibility criteria were as per current NCCN guidelines, less stringent qPCR monitoring scheduled every 3 months. TFR was...
Abstract Background To analyze the spectrum of various types and subtypes acute leukemia. Methods Two thousand five hundred eleven consecutive new referral cases leukemia (AL) were evaluated based on WHO classification. Results It included 1,471 (58%) lymphoblastic (ALL), 964 (38%) myeloid (AML), 45 (1.8%) chronic myelogenous in blast crisis (CMLBC), 37 (1.5%) biphenotypic (BAL), 1 case Triphenotypic AL, 2 undifferentiated (AUL). Common ALL B‐cell (76%), which comprised intermediate...
Summary Tyrosine kinase inhibitors (TKIs) have drastically improved the outcomes of pCML (paediatric CML) but data on long‐term off‐target toxicities TKIs in children are scarce. In this single‐centre, retrospective cum prospective study chronic phase, we report our experience treating 173 with imatinib and following them for toxicities. Mean (SD) time to attain CHR, CCyR MMR were 3.05 (2.1), 10.6 (8.4) 43.4 (31.8) months respectively. DMR was not attained 59 (34%) patients at last...
Seeds of hulled barley (Hordeum vulgare) were germinated and then treated with LSD. Preparations squashed root tips stained Feulgen revealed extensive chromosomal aberrations, most which chromosome breaks. Nearly half the breaks occurred in region primary constriction.
The present study of 238 B-cell Chronic Lymphocytic Leukemia (B-CLL) patients were undertaken to seek the prevalence and evaluate clinico-pathological significance recurrent genetic abnormalities such as del(13q14.3), trisomy 12, del(11q22.3) (ATM), TP53 deletion, del(6q21) IgH translocation/deletion.We applied interphase - fluorescence in situ hybridization (FISH) on total cases B-CLL.Our disclosed 69% with aberrations 13q deletion (63%), 12 (28%), 11q (18%), 6q21 (11%) comparatively higher...
Asymmetry of the karyotype combined with x-ray induced interchange heterozygosity has been made use in Delphinium to study relationship between chiasmata and crossing-over. The tranalocation muitiples two heterozygous plants were analyzed for chiasma formation interstitial segments, equational reductional separation chromosomes having these segments. A close correspondence frequency that chromatids was found first heterozygote. In second, invariable non-formation regions be associated...
Study on the susceptibility of 20 maize varieties against Angoumois grain moth, Sitotroga cerealella (Olivier) was carried out under No-choice test method. The assessed basis moth emergence, developmental period, insect weight, weight flour, loss, damage and nutritional indices. Besides, biochemical characters grains were analyzed. Results showed that Pratap makka-5 most resistant variety with longest time 38.36 days, least adult emergence 3.5, lowest index 2.88, minimum 7.21% loss 1.45%...
Multiple myeloma (MM) is a plasma cell malignancy characterized by cytogenetic heterogeneity. In comparison with conventional karyotyping, fluorescence in situ hybridization (FISH) can efficiently detect various genetic changes non-cycling cells 50-90 per cent of MM cases. The present study was undertaken patients to evaluate the frequency and clinico-pathological significance abnormalities Indian population.Interphase FISH applied on purified 475 using specific probes. Interphase for 1q...