A5031034758- Sarcoma Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Breast Cancer Treatment Studies
- Esophageal Cancer Research and Treatment
- Management of metastatic bone disease
- COVID-19 and healthcare impacts
- Lymphoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Cardiac tumors and thrombi
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- COVID-19 and Mental Health
- Economic and Financial Impacts of Cancer
- Cancer Risks and Factors
- Nutrition and Health in Aging
- Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Breast Lesions and Carcinomas
- Advanced Radiotherapy Techniques
- Metastasis and carcinoma case studies
- Neutropenia and Cancer Infections
- Fungal Infections and Studies
Tata Memorial Hospital
2020-2024
Homi Bhabha National Institute
2020-2024
Advanced Centre for Treatment, Research and Education in Cancer
2020-2023
Creative Commons
2022
Max Healthcare
2022
We report the clinical outcomes of a randomized trial comparing prophylactic whole-pelvic nodal radiotherapy to prostate-only (PORT) in high-risk prostate cancer.This phase III, single center, controlled enrolled eligible patients undergoing radical for node-negative adenocarcinoma, with estimated risk ≥ 20%. Randomization was 1:1 PORT (68 Gy/25# prostate) or (WPRT, 68 prostate, 50 pelvic nodes, including common iliac) using computerized stratified block randomization, by Gleason score, type...
Abstract The use of pediatrics-inspired protocols in adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) results superior survival compared with the protocols. Pediatrics-inspired carry an increased risk toxicity treatment-related mortality low resource settings, which can offset potential benefits. We studied outcomes prognostic factors treatment AYA ALL a regimen. retrieved data regarding demographics, investigations, details, toxicities from electronic medical records...
BackgroundPregnancy associated breast cancer (PABC) is a rare entity and defined as diagnosed during pregnancy or one-year post-partum. There sparse data especially from low middle-income countries (LMIC) merits exploration.MethodsThe study (2013–2020) evaluated demographics, treatment patterns outcomes of PABC.ResultsThere were 104 patients, median age 31 years; 43 (41%) had triple-negative disease, 31(29.8%) hormone-receptor (HR) positive HER2 negative, 14 (13.5%) HER2-positive HR negative...
There is scant data from India on efficacy and safety of palbociclib ribociclib in routine clinical practice.This retrospective, observational, single institution study included patients with estrogen and/or progesterone receptor positive human epidermal growth factor 2 (HER2) negative metastatic breast cancers, who received or any partner endocrine therapy line treatment between January 2016 June 2019. Data were analyzed for progression-free survival (PFS), overall (OS) toxicity.The 101...
Image-based prediction of molecular subgroups Medulloblastoma (MB) has the potential to optimize and personalize therapy. The objective study is distinguish between broad MB using MR-Texture analysis.Thirty-eight patients treated 2007 2020 were retrospectively analyzed. Texture analysis was performed on contrast enhanced T1(T1C) T2 weighted (T2W) MR images. Manual segmentation all slices radiomic features extracted which included first order, second order (GLCM - Grey level co-occurrence...
Amit JoshiBackground Cancer is one of the most expensive and exhaustive medical conditions with a huge impact on financial condition patient their family members. A lot advancements have led to improvement in survival patients but at raised cost. Comprehensive Score for Toxicity - Functional Assessment Chronic Illness Therapy (COST FACIT Version 2) such validated widely used tool. Assessing burden our country still far more challenging as COST available English language not any regional...
Background: During the coronavirus disease 2019 (COVID-19) pandemic, established best practices in cancer care were modified to diminish risk of COVID-19 infection among patients and health-care workers. Objective: We aimed study modifications cancer-directed therapy during first wave pandemic. Materials Methods: A cross-sectional with cancers head neck, thoracic, urologic, central nervous systems who visited medical oncology department Tata Memorial Hospital, Mumbai, India, between April...
PURPOSE To evaluate stress levels among the health care workers (HCWs) of radiation oncology community in Asian countries. METHODS HCWs departments from 29 tertiary cancer centers Bangladesh, India, Indonesia and Nepal were studied May 2020 to July 2020. A total 758 eligible identified. The 7-Item Generalized Anxiety Disorder, 9-Item Patient Health Questionnaire, 22-Item Impact Events Scale-Revised used for assessing anxiety, depression, post-traumatic disorder. Univariate multivariate...
Outcome and toxicity data in adolescent-adult Ewing sarcoma (AA-ES) patients are sparse merits exploration.Histopathologically confirmed, nonmetastatic AA-ES patients, who received standard institutional combination chemotherapy regimen (Ewing's family of tumors-2001 [EFT-2001]) comprising ifosfamide plus etoposide vincristine, doxorubicin cyclophosphamide, lasting a total 12 months between 2013 2018, were analyzed for treatment-related toxicities, event-free survival (EFS), overall...
Background There are limited data on the role of chemotherapy in patients with small cell lung cancer (SCLC) and poor performance status (PS).Methods This was a retrospective analysis prospective observational study SCLC PS 3 or 4. We recorded initial therapy, symptom improvement, response rate, overall survival (OS), impact various factors OS.Results From June 2010 to August 2019, we enrolled 234 patients; 185 (79%) 49 (21%) Initial therapy best supportive care (BSC) (21%), standard full...
Radiotherapy for brain tumors in young patients is not only associated with improved survival but also long-term neurocognitive sequelae. We aimed to compare group differences the executive outcomes low-grade treated stereotactic conformal radiotherapy (SCRT) and conventional RT (ConvRT) techniques.This a phase 3 randomized trial that enrolled 200 benign gliomas. Patients were randomly allocated (1:1) either SCRT or ConvRT arms dose of 54 Gy 30 fractions over 6 weeks. Lowenstein Occupational...
Introduction:The data on outcomes and toxicity in adult Ewing sarcoma (ES) patients, particularly those aged ≥40 years, is exceedingly scarce around the world, low-and middle-income countries (LMICs) mandates research. Methods:The study involved histologically ascertained ES patients years who registered at our institute from 2013 to 2018.Prospectively collected were analysed for overall survival (OS), event-free (EFS) chemotherapy-related toxicities.Results: There 66 of which 34...
The role of consolidation radiation therapy (CRT) after complete metabolic response to chemotherapy in advanced-stage (stage III and IV) Hodgkin lymphoma (HL) is controversial. This study was undertaken assess the clinical outcomes terms event free survival, local failure survival overall individuals with advanced HL treated CRT.