A5100694564- Photosynthetic Processes and Mechanisms
- Photoreceptor and optogenetics research
- Spectroscopy and Quantum Chemical Studies
- MicroRNA in disease regulation
- Advanced biosensing and bioanalysis techniques
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- RNA Interference and Gene Delivery
- Bioactive natural compounds
- Microtubule and mitosis dynamics
- Axon Guidance and Neuronal Signaling
- Lipid metabolism and biosynthesis
- Neurobiology and Insect Physiology Research
- Molecular spectroscopy and chirality
- RNA and protein synthesis mechanisms
- Metabolism, Diabetes, and Cancer
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Spectroscopy Techniques in Biomedical and Chemical Research
- Cancer-related gene regulation
- Biosensors and Analytical Detection
- Caveolin-1 and cellular processes
- DNA and Nucleic Acid Chemistry
- Epigenetics and DNA Methylation
- Spectroscopy and Chemometric Analyses
Henan Provincial People's Hospital
2015-2025
Zhengzhou University
2014-2025
Henan University
2025
Beijing Polytechnic
2023-2024
Ministry of Education of the People's Republic of China
2024
Northwest University
2024
Second Affiliated Hospital of Xi'an Jiaotong University
2018-2021
Kunming Medical University
2012-2021
Southwest University
2021
Liaocheng People's Hospital
2020
Abstract Background Small extracellular vesicles (sEV) are closely associated with the development and metastasis of many types mammalian cancer. Glycoconjugates highly expressed on sEV play important roles in biogenesis their interaction other cells. However, study vesicular glycoconjugates far behind proteins nucleic acids. Especially, functions sialic acids which terminal components glycoconjugates, poorly understood sEV. Methods Sialic acid levels from plasma bladder cancer cells were...
To evaluate the efficacy of a combination Ovarian-Adnexal Reporting and Data System (O-RADS), contrast-enhanced ultrasound (CEUS), cancer antigen 125 (CA125) in identifying malignant ovarian-adnexal lesions improving diagnostic accuracy, providing reliable reference for evaluation management malignancies to enhance patient prognosis. The study analyzed performance O-RADS alone with CEUS CA125 distinguishing between benign lesions. Sensitivity, specificity, Kappa values were calculated assess...
Iris domestica is a perennial herb valued for both its ornamental and medicinal properties. Despite significance, no comprehensive analysis of mitochondrial genome has been previously reported. Plant genomes are known their large size, structural complexity, frequent recombination events. This study aims to provide the first complete assembly characterization I. domestica, with focus on structure, gene content, repeat elements, RNA editing sites. We used GetOrganelle Unicycler software...
Several adult reptiles, such as Gekko japonicus, have the ability to precisely re-create a missing tail after amputation. To ascertain associated acquisition of positional information from blastemal cells and underlying molecular mechanism regeneration, candidate molecule CD59 was isolated gecko. transcripts displayed graded expression in gecko spinal cord with highest level anterior segment, stable along normal tail. After amputation, proximal injury sites increased markedly at 1 day 2...
The primary electron donor of photosystem I (PS1), called P700, is a heterodimer chlorophyll (Chl) and a'. crystal structure reveals that the a' (PA) could be hydrogen-bonded to protein via threonine residue, while (PB) does not have such hydrogen bond. To investigate influence this bond on PsaA-Thr739 was converted alanine remove H-bond 131-keto group in Chlamydomonas reinhardtii. PsaA-T739A mutant capable assembling active PS1. Furthermore PS1 contained approximately one molecule per...
Abstract Infrared spectroscopy of biological cell monolayers grown on surfaces is a poorly developed field. This unfortunate because these have potential as sensors. Here we used infrared microscopy, in both transmission and transflection geometries, to study air‐dried Vero monolayers. Using methods allows one distinguish sampling artefactual features from real sample spectral features. In experiments, amide I/II absorption bands down‐shift 9/4 cm −1 , respectively, relative the...
Herein, an ultra-sensitive and facile electrochemical biosensor for procalcitonin (PCT) detection was developed based on NiCoP/g-C3N4 nanocomposites. Firstly, nanocomposites were synthesized using hydrothermal methods then functionalized the electrode surface by π-π stacking. Afterward, monoclonal antibody that can specifically capture PCT successfully linked onto of with a 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) N-Hydroxysuccinimide (NHS) condensation reaction....
Time-resolved step-scan Fourier transform infrared (FTIR) difference spectroscopy, with 5 μs time resolution, has been used to produce P700+A1-/P700A1 FTIR spectra in intact photosystem I particles from Synechococcus sp. 7002 and Synechocystis 6803 at 77 K. Corresponding were also obtained for fully deuterated as well 15N- 13C-labeled 6803. Static P700+/P700 K all of the unlabeled labeled particles. From time-resolved static spectra, A1-/A1 constructed. The trimeric both cyanobacterial...
Ischemic brain injury results in high mortality and serious neurologic morbidity. Here, we explored the role of SNHG15 modulating neuronal damage microglial inflammation after ischemia stroke.The hypoxia/ischemia models were induced by middle cerebral artery occlusion mice oxygen-glucose deprivation/reoxygenation (OGD/R) vitro. Quantitative real-time PCR (qRT-PCR) Western blot conducted to determine levels SNHG15, miR-302a-3p, STAT1/NF-κB. Moreover, gain- or loss-of functional assays...
Roxithromycin (RXM) has been widely used in asthma treatment; however, the mechanism not fully understood. The aim of our study was to investigate underlying RXM treatment mediating effect transforming growth factor (TGF)-β1 on airway smooth muscle cells (ASMCs) proliferation and caveolinn-1 expression.Firstly, rat ovalbumin (OVA) model built according previous papers. Rat ASMCs were prepared cultured, then TGF-β1 production measured by enzyme-linked immunosorbent assay (ELISA). Moreover,...
Chlorophyll a (Chl-a) is at the heart of solar energy capture and conversion in plants. Because this, Chl-a has been subject innumerable studies. Recently, we have able to use quantum mechanical methods calculate vibrational properties neutral oxidized gas phase [Wang, R.; Parameswaran, S.; Hastings, G. Vib. Spectrosc. 2007, 44, 357−368]. The calculated do not agree with experiment, however. One factor ignored our calculations was how solvents could impact properties. Here Chl-a+ several...