A5058654304- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pleural and Pulmonary Diseases
- Neuroendocrine Tumor Research Advances
- Inhalation and Respiratory Drug Delivery
- Antifungal resistance and susceptibility
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Treatments and Mutations
- Cardiac tumors and thrombi
- Mycobacterium research and diagnosis
- Respiratory Support and Mechanisms
- Fungal Infections and Studies
- Vascular Anomalies and Treatments
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Mycology
- Medical Imaging Techniques and Applications
- Vasculitis and related conditions
- IgG4-Related and Inflammatory Diseases
- Pneumonia and Respiratory Infections
- Occupational and environmental lung diseases
- Occupational exposure and asthma
- Tuberculosis Research and Epidemiology
Fukujuji Hospital
2016-2025
Japan Anti Tuberculosis Association
2016-2024
Kumamoto University
2021
Kumamoto University Hospital
2021
Toranomon Hospital
2003-2020
Mito Saiseikai General Hospital
2006
University Radiology
2000
University of Tsukuba
1993
Pulmonary tumor thrombotic microangiopathy (PTTM) is a unique, rare and fatal form of pulmonary arterial embolism. The aim this study was to evaluate the clinical characteristics pathological immunohistochemical findings PTTM.Autopsy records dated between January 1983 May 2008 in our hospital were reviewed, those patients who died from embolism resulting malignant neoplasm retrieved. relevant tissue slides reevaluated examined immunohistochemically confirm diagnosis.Among 2,215 consecutive...
Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is considered to be a nearly fatal condition during the clinical course IPF, as it unresponsive most conventional therapies.To evaluate efficacy cyclosporin A (CsA) for AE we conducted retrospective study on autopsied IPF cases who developed and were treated with corticosteroids (CS) combined CsA. The subjects comprised 11 males mean age 69.9 years. features prognosis CsA-treated group was compared 68.7 years CS alone...
Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) can be fatal, and abnormalities in the coagulation system patients with AE-IPF have been reported. Recombinant human soluble thrombomodulin (rhTM) forms a complex thrombin to inactivate coagulation. It also inhibits high-mobility group box protein 1 (HMGB-1), which results suppression inflammation.We aimed evaluate effectiveness rhTM for treatment AE-IPF.We retrospectively reviewed medical records 41 who were admitted our...
Chest High-Resolution CT Findings of Microscopic Polyangiitis: A Japanese First Nationwide Prospective Cohort StudyAika Suzuki1, Susumu Sakamoto1, Atsuko Kurosaki2, Yasuyuki Kurihara3, Keita Satoh4, Yusuke Usui1, Toshihiro Nanki5, Yoshihiro Arimura6, Hirofumi Makino7, Yasunori Okada8, Masayoshi Harigai9, Kunihiro Yamagata10, Hitoshi Sugiyama11, Hiroaki Dobashi12, Akihiro Ishizu13, Naotake Tsuboi14, Joichi Usui15, Ken-ei Sada16, Sakae Homma1 and for Japan Research Committee the Ministry...
Background Acute exacerbation (AE) of idiopathic interstitial pneumonia (IIP) is occasionally observed after lung surgery. However, the risk surgery in patients with IIPs not yet clearly known. Subjects and Methods We conducted a retrospective study consecutive who underwent for cancer or diagnosis (IP) between 2000 2006. Patients developed AE following operation were assessed. Results The data 68 (males: 56, females: 12) IP analyzed. included lobectomy 48 [idiopathic pulmonary fibrosis...
<title>Abstract</title> <bold>Background</bold>: The guideline recommends the addition of amikacin liposome inhalation suspension (ALIS) to guideline-based therapy for patients with refractory <italic>Mycobacterium avium</italic> complex pulmonary disease (MAC-PD). real-world data on treatment efficacy and safety ALIS remain insufficient. <bold>Research Question</bold>: What factors influence culture conversion during ALIS, what are best practices managing ALIS-related adverse events,...
The purpose of this study was to evaluate high-resolution computed tomography (HRCT) findings lung cancer associated with idiopathic pulmonary fibrosis (IPF).Thirty patients who had preceding IPF and were receiving regular follow-up between 1993 2002 examined. Medical records, radiographs (including HRCT scans), histologic slides reviewed.In 28 the 30 patients, most common pattern a nodular lesion soft tissue attenuation. Nodule margins well defined in 23 lesions (82.1%), lobulation 24...
To assess diaphragmatic motion during forced breathing in a health screening center cohort by time-resolved quantitative analysis using dynamic chest radiography and demonstrate the characteristics associations with demographics pulmonary function of participants.This prospective study includes 174 volunteers (99 males; median 57, range 36-93 years old) that underwent flat panel detector system standing position. We automatically tracked recorded positions top diaphragms excursions on images...
Rationale: There is a growing need to accurately estimate the prognosis of idiopathic pulmonary fibrosis (IPF) in clinical practice, given development effective drugs for treating IPF. Objectives: To develop artificial intelligence-based image analysis software detect parenchymal and airway abnormalities on computed tomographic (CT) imaging chest explore their prognostic importance patients with Methods: A novel quantitative CT (AIQCT) was developed by applying 304 high-resolution (HRCT)...
Dynamic X-ray (DXR) provides images of multiple phases breath with less radiation exposure than CT. The exact at end-inspiratory or end-expiratory can be chosen accurately.To investigate the correlation projected lung area (PLA) by dynamic chest pulmonary functions.One hundred sixty-two healthy volunteers who received medical check-ups for health screening were included in this study. All subjects underwent DXR both posteroanterior (PA) and lateral views function tests on same day. took...
Abstract Approximately one-third of fibrosing interstitial lung diseases exhibit progressive pulmonary fibrosis (PPF), a clinicopathological condition distinct yet resembling idiopathic (IPF). PPF in ANCA-positive ILD (ANCA-ILD) is poorly documented. To clarify incidence, predictors ANCA-ILD, and their prognostic impact, 56 patients with ANCA-ILD were followed for ≥ 1 year (April 2004 to April 2021). was defined per ATS/ERS/JRS/ALAT 2022 guideline. We compared non-PPF 38 function tests...
To retrospectively evaluate the efficacy and safety of gefitinib in elderly patients with advanced non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor mutations.Nine aged 70 years or older who had NSCLC mutations gene were treated gefitinib, 250 mg daily. Clinical data, types mutations, toxicity evaluated these patients. Tumor responses assessed by computed tomography scan using Response Evaluation Criteria Solid Tumors.Six showed a partial response, other three...
Mycobacterium abscessus (M. abscessus) pulmonary disease is a refractory chronic infectious disease. Options for treating M. are limited, especially in outpatient settings. Among parenteral antibiotics against abscessus, intravenous amikacin (AMK) expected to be an effective antimicrobial therapy. This study evaluated the clinical efficacy and safety of AMK therapy outpatients with retrospective chart review cases patient background data, dosage duration, sputum conversion, symptoms...
Five patients with solitary fatty mass of the pancreas examined CT and ultrasound (US) were evaluated. The areas fat replacement located in pancreatic neck, body or tail. size ranged from 4 to 30 mm longest diameter. shape varied roundish, ovoid semicircular, contour was universally well defined. internal structure homogeneous 3 patients, but one case there thin septa and, another, a slightly hyperdense part peripheral portion. All masses except smallest contact fat. showed same density as...
Abstract Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is often fatal. A straightforward staging system for AE-IPF would improve prognostication, guide patient management, and facilitate research. The aim study to develop a multidimensional prognostic that uses commonly measured clinical variables. This retrospective analyzed data from 353 consecutive patients with IPF admitted our hospital during the period January 2008 through 2018. Multivariate analysis information database...
Objective The purpose of this study was to evaluate the usefulness CT in making a diagnosis systemic arterial supply normal basal segments left lower lobe. Materials and Methods We retrospectively reviewed chest radiography (three cases), angiography (two cases). Results An anomalous artery arising from descending aorta shown as retrocardiac density on posteroanterior nodular behind heart lateral radiography. Contrast enhanced revealed vascular nature adjacent aorta. Dynamic one patient...