A5103231035- Soil Carbon and Nitrogen Dynamics
- Advanced biosensing and bioanalysis techniques
- Rangeland Management and Livestock Ecology
- Auction Theory and Applications
- Amino Acid Enzymes and Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Photoreceptor and optogenetics research
- Plant Ecology and Soil Science
- Tryptophan and brain disorders
- Soil and Environmental Studies
- RNA Research and Splicing
- Chemical Reactions and Isotopes
- Cardiac Ischemia and Reperfusion
- Anesthesia and Neurotoxicity Research
- Molecular Junctions and Nanostructures
- DNA and Nucleic Acid Chemistry
- Epigenetics and DNA Methylation
- Biosensors and Analytical Detection
- RNA modifications and cancer
- Quantum Dots Synthesis And Properties
- Autophagy in Disease and Therapy
- RNA and protein synthesis mechanisms
Northeast Agricultural University
2024
Zhejiang University
2023
Faculty of 1000 (United States)
2022
Changzhou University
2018
Institute of Psychology, Chinese Academy of Sciences
2017
Guangxi Normal University
2014
Soochow University
2009
Large Language Models (LLMs) have shown impressive reasoning capabilities in well-defined problems with clear solutions, such as mathematics and coding. However, they still struggle complex real-world scenarios like business negotiations, which require strategic reasoning-an ability to navigate dynamic environments align long-term goals amidst uncertainty. Existing methods for face challenges adaptability, scalability, transferring strategies new contexts. To address these issues, we propose...
T cells require rapid proliferation to initiate adaptive immunity prevent pathogen attacks. The nucleolus, a distinct subnuclear membrane-less compartment for ribosomal biogenesis, is indispensable cell proliferation. However, specific nucleolar proteins involved in and their underlying molecular regulatory mechanism remain elusive. Here, we identified an essential protein, DCAF13, revealed its significant regulation of Its depletion drastically impairs due severe 18S rRNA maturation...
The roles of D-serine in depression are raised concerned recently as an intrinsic co-agonist for the NMDA receptor. However, mechanisms underlying its regulation not fully elucidated. ASCT2 is a Na+-dependent transporter. We found that decreased and increased hippocampal levels correlated with chronic social defeat stress (CSDS) mice. Lentivirus-mediated shRNA-mediated knockdown administration exogenous hippocampus alleviated CSDS-induced avoidance immobility. In vivo vitro experiments...
Abstract Here, we combine T7 exonuclease (T7 Exo) signal amplification and polystyrene nanoparticle (PS NP) to develop novel fluorescence polarization (FP) aptasensors. The binding of a target/open aptamer hairpin complex or target/single‐stranded dye‐labeled DNA bound PS NPs, the self‐assembly two subunits (one them labeled with dye) into target/aptamer on NPs leads cyclic Exo‐catalyzed digestion subunit. This results in substantial decrease FP value for amplified sensing process. Our newly...
Abstract Despite the numerous techniques developed for studying nanoparticle and peptide interaction nowadays, sensitive convenient assay in process of flow, especially to simulate self‐assembly quantum dots (QDs) inflow blood vessels, still remains big challenges. Here, we report a novel QDs peptide, based on CE using bending capillary. We demonstrate that semicircles numbers capillary affect kinetics CdSe/ZnS ATTO‐D 3 LVPRGSGP 9 G 2 H 6 peptide. Moreover, benefitting from this assay,...