- Cytokine Signaling Pathways and Interactions
- Cardiac Fibrosis and Remodeling
- Autophagy in Disease and Therapy
- Cardiovascular Function and Risk Factors
- Cardiac Ischemia and Reperfusion
- Cellular transport and secretion
- Calpain Protease Function and Regulation
- Phagocytosis and Immune Regulation
Zhujiang Hospital
2024
Southern Medical University
2024
Tianjin Medical University General Hospital
2024
Abstract Aerobic training (AT), an effective form of cardiac rehabilitation, has been shown to be beneficial for repair and remodeling after myocardial infarction (MI). The p300/CBP‐associated factor (PCAF) is one the most important lysine acetyltransferases involved in various biological processes. However, role PCAF AT AT‐mediated post‐MI not determined. Here, we found that protein level was significantly increased MI, while blocked increase PCAF. markedly improved mice MI by reducing...
Cartilage degradation is a critical alteration in the progression of osteoarthritis (OA) due to disorder chondrocyte metabolic homeostasis. Autophagy plays an important role maintaining intracellular Recent investigations have increasingly underscored importance autophagy modulating pathological mechanisms underlying OA. Ras-related protein Rab-1a (Rab1a) has been illustrated regulate many diseases but not