Yuan Hu

ORCID: 0000-0002-8951-5881
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Research Areas
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research
  • Insect-Plant Interactions and Control
  • RNA modifications and cancer
  • Advanced Photocatalysis Techniques
  • Insect Resistance and Genetics
  • Hippo pathway signaling and YAP/TAZ
  • Synthetic Organic Chemistry Methods
  • Cancer Mechanisms and Therapy
  • Catalytic Alkyne Reactions
  • Phytochemistry and Biological Activities
  • Chemical synthesis and alkaloids
  • Ubiquitin and proteasome pathways
  • Insect and Pesticide Research
  • Phytochemistry and Bioactive Compounds
  • Biological Activity of Diterpenoids and Biflavonoids
  • Hepatitis B Virus Studies
  • Natural product bioactivities and synthesis
  • Synthesis of Organic Compounds
  • Histone Deacetylase Inhibitors Research
  • Corporate Social Responsibility Reporting
  • 14-3-3 protein interactions
  • Phytochemical compounds biological activities
  • Cardiac, Anesthesia and Surgical Outcomes

Zunyi Medical University
2024-2025

Sichuan University
2022-2024

West China Second University Hospital of Sichuan University
2024

University of Science and Technology Liaoning
2024

Shaoxing University
2024

Shanghai Jiao Tong University
2012-2023

Shanghai University of Traditional Chinese Medicine
2023

Chinese PLA General Hospital
2017-2023

Lanzhou University
2023

Jiangxi Normal University
2009-2022

Purpose This paper aims to examine the relationship between ownership type and likelihood of publication a corporate social responsibility (CSR) report. Design/methodology/approach Drawing on stakeholder salience theory, probit model is used for sample 1,839 Chinese listed firms study how different types owners influence firm CSR engagement. Findings The analysis reveals that stock exchanges exert positive producing report, an effect which more significant in state-owned enterprises (SOEs)....

10.1108/arj-01-2017-0011 article EN Accounting Research Journal 2018-05-08

In this work, the feasibility of using transition metal doped C9N4 as an efficient gas sensor is comprehensively investigated by density functional theory methods. Firstly, calculated Ef and Udiss values show that most M-C9N4 M2-C9N4 have good thermodynamic electrochemical stability. Secondly, for CO, NO, NO2, NH3, H2S on Cr-C9N4, Eads are −2.07, −3.05, −2.53, −1.76, −2.14 eV, respectively. For these gases Fe2-C9N4, −2.60, −3.07, −2.45, −2.39, −2.21 The results Cr-C9N4 Fe2-C9N4 adsorption...

10.1016/j.colsurfa.2024.133716 article EN cc-by-nc-nd Colloids and Surfaces A Physicochemical and Engineering Aspects 2024-03-13

Epidermal growth factor receptor (EGFR) overexpression and activation result in increased proliferation migration of solid tumors including ovarian cancer. In recent years, mounting evidence indicates that EGFR is a direct functional target miR-7. this study, we found miR-7 expression was significantly downregulated highly metastatic epithelial cancer (EOC) cell lines tissues, whereas the of, correlated positively with metastasis both EOC patients lines. Overexpression markedly suppressed...

10.1371/journal.pone.0096718 article EN cc-by PLoS ONE 2014-05-09

The coronavirus disease-19 (COVID-19) pandemic has had a significant impact on human life worldwide since 2019. Specific vaccines and antiviral agents are the most effective means of preventing treating severe acute respiratory syndrome 2 (SARS-CoV-2) infections. Additionally, protective equipment early diagnosis also contribute to controlling spread COVID-19. utilization biomaterials in medicine pharmaceuticals is crucial ensure positive vaccines, agents, equipment. In this review, we...

10.1021/acsomega.3c08326 article EN cc-by-nc-nd ACS Omega 2024-01-26

A novel approach was developed for the synthesis of 2-substituted-3-functionalized benzofurans, using an intramolecular Heck reaction which further applied in first enantioselective total Daphnodorin B.

10.1021/ol4021095 article EN Organic Letters 2013-09-05

Glioma is the most common primary malignant tumor of central nervous system, which results in both a poor prognosis and outcome because aggressive progression disease, growth resistance to surgery, chemotherapy, radiotherapy. MiR-140-5p small, non-coding single-stranded RNA molecule, was previously studied settings human tongue cancer, hepatocellular carcinoma, colorectal cancer. However, detailed data that formally demonstrate contribution miR-140-5p glioma development are missing....

10.1177/1010428317697558 article EN cc-by-nc Tumor Biology 2017-04-01

Abstract BACKGROUND Acaricide resistance is a serious problem in spider mites. Cyflumetofen new complex II inhibitor, whereas pyridaben acts at I and has been used for decades. Although cross‐resistance between cyflumetofen observed Tetranychus cinnabarinus , the specific mechanisms play have not yet investigated. RESULTS Investigation into identified five P450s, among which CYP389C16 was evaluated as most likely candidate conferring cross‐resistance. Knockdown of expression via RNA...

10.1002/ps.5564 article EN Pest Management Science 2019-08-07

Whitefly (Bemisia tabaci) is a typical pest that causes severe damage to hundreds of agricultural crops. The trehalose-6-phosphate synthase (TPS) genes, as the key genes in insect trehalose synthesis pathway, are important for growth and development. whitefly TPS may be main reason represent potential targets control whiteflies.In this study, we identified cloned three from B. tabaci MED found BtTPS1 BtTPS2 showed higher expression levels than BtTPS3 gene. Then, RNA interference (RNAi)...

10.1002/ps.6727 article EN Pest Management Science 2021-11-19

As one of the common malignant cancer types, gastric (GC) is known for late-stage diagnosis and poor prognosis. Overexpression receptor tyrosine kinase MET associated with prognosis among patients advanced stage GC. However, no inhibitor has been used GC treatment. Like other inhibitors that fit "occupancy-driven" model, current are prone to acquired resistance. The emerging proteolysis targeting chimera (PROTAC) strategy could overcome such limitations through direct degradation target...

10.1111/cas.15733 article EN cc-by-nc-nd Cancer Science 2023-01-24

Pseudolaridimers A (1) and B (2), two unprecedented heterodimers formed via a [4 + 2] Diels–Alder cycloaddition between cycloartane triterpenoid unit labdane diterpenoid unit, were isolated from the cones of Pseudolarix amabilis. Their structures established by extensive analysis HRESIMS NMR spectra. The absolute configuration 1 was determined single crystal X-ray diffraction (CuKα) its methyl esterified derivative. Pseudolaridimer showed strong cytotoxicity against HCT116, ZR-75-30, HL-60...

10.1021/ol302501a article EN Organic Letters 2012-10-17

Abstract A mild and operationally simple procedure by Pd-catalyzed cross-coupling of acyl chlorides with in situ–generated alkynylzinc derivatives was developed, giving the corresponding ynones good yields. Supplementary materials are available for this article. Go to publisher's online edition Synthetic Communications® full experimental spectral details.

10.1080/00397911.2012.745156 article EN Synthetic Communications 2013-07-08

Previous studies on motivations for corporate environmental disclosure ( CED ) in emerging countries are generally undertheorized and have neglected to investigate disincentives. This study addresses this gap using legitimacy theory determine whether differences exist between Chinese Malaysian managers relation incentives disincentives . Our findings reveal that suggesting legitimization strategies, if employed, vary perceptions of threat differ countries. The also reports the dominating...

10.1002/tie.21678 article EN Thunderbird International Business Review 2015-01-22

Endometrial cancer represents the leading frequency in gynecological malignancy developed countries. Even with early detection, metastasis and recurrence remain main reasons for a high death rate. MicroRNA-449a (miR-449a) has been reported to function as tumor suppressor, yet role of miR-449a endometrial not investigated. The present study identified that was downregulated advanced cancer. Overexpression decreased migration invasion KLE AN3CA cells. Using luciferase reporter assays, we...

10.7150/jca.27748 article EN cc-by-nc Journal of Cancer 2019-01-01
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