A5100768914- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Energy, Environment, Economic Growth
- Endometriosis Research and Treatment
- Acute Kidney Injury Research
- Environmental Impact and Sustainability
- RNA and protein synthesis mechanisms
- Retinoids in leukemia and cellular processes
- Environmental Sustainability in Business
- Inflammatory mediators and NSAID effects
- Plant Stress Responses and Tolerance
- Bee Products Chemical Analysis
- Circadian rhythm and melatonin
- Renal Diseases and Glomerulopathies
- Diet, Metabolism, and Disease
- Drug-Induced Hepatotoxicity and Protection
- Sirtuins and Resveratrol in Medicine
- Essential Oils and Antimicrobial Activity
- Educational Reforms and Innovations
- Ovarian cancer diagnosis and treatment
- Spondyloarthritis Studies and Treatments
- Insect and Pesticide Research
- Chemotherapy-induced organ toxicity mitigation
- Cell death mechanisms and regulation
- Environmental Education and Sustainability
Shihezi University
2025
First Affiliated Hospital of Shihezi University Medical College
2024
Second Affiliated Hospital of Zhejiang University
2017-2024
Air Force Medical University
2024
Second Hospital of Shandong University
2022-2024
Women's Hospital, School of Medicine, Zhejiang University
2018-2023
Chinese Academy of Fishery Sciences
2022-2023
Sanya University
2022-2023
Wuxi Vocational Institute of Commerce
2021-2023
China University of Mining and Technology
2011-2022
Epidermal growth factor receptor (EGFR) overexpression and activation result in increased proliferation migration of solid tumors including ovarian cancer. In recent years, mounting evidence indicates that EGFR is a direct functional target miR-7. this study, we found miR-7 expression was significantly downregulated highly metastatic epithelial cancer (EOC) cell lines tissues, whereas the of, correlated positively with metastasis both EOC patients lines. Overexpression markedly suppressed...
In this work, the potential of mineral elements and chemometric methods as a tool to classify Chinese honeys according their botanical origin was examined. Twelve (Na23, Mg24, P31, K39, Ca43, Mn55, Fe56, Cu63, Zn66, Rb85, Sr88, Ba137) 163 honey samples, including linden, vitex, rape, acacia, collected from Heilongjiang, Beijing, Hebei, Shaanxi, China, in 2013 were determined by ICP-MS method. Principal component analysis (PCA) reduced 10 variables four principal components could explain...
Gestational diabetes mellitus (GDM) is one of the most common complications during pregnancy and has been on a continuous increase in recent years. This study aimed to establish combined prediction model for risk GDM provide more reliable reference information non-invasive assessment clinical practice. retrospectively collected data ultrasound 122 pregnant women who underwent fetal nuchal translucency screening, which divided into 36 cases group 86 non-gestational mellitus(NGDM) group. The...
Nonalcoholic fatty liver disease (NAFLD) is a common that currently has no standard treatment. The present study aimed to evaluate the effects of Lycium ruthenicum extract (LRE) on high‑fat diet (HFD)-induced NAFLD, and elucidate underlying molecular mechanisms. To determine hepatoprotective effect LRE, C57BL/6 mice were fed normal control diet, (HFD), HFD supplemented with 2 g/kg or 5 LRE. Treatment LRE markedly decreased levels triglycerides, total cholesterol, aspartate aminotransferase...
Hepatic ischemia reperfusion (IR) injury contributes to the morbidity and mortality associated with liver surgery. This study investigated protective function mechanism of propylene glycol alginate sodium sulfate (PSS), a sulfated polysaccharide, in mouse hepatic IR model. PSS (25 or 50 mg/kg) saline were injected intraperitoneally male Balb/c mice 1 h before 45 min 70% warm 2, 8, 24 reperfusion. Serum tissue samples collected for evaluation hepatocellular damage, histology, assay...
Hormone receptor-positive breast cancer (HR
L-3, 4-dihydroxyphenylalanine (L-dopa) is the gold standard for symptomatic treatment of Parkinson's disease (PD), but long-term therapy associated with emergence L-dopa-induced dyskinesia (LID). In present study, L-dopa and benserazide were loaded by poly (lactic-co-glycolic acid) microspheres (LBM), which can release levodopa in a sustained manner order to continuous stimulate dopaminergic receptors. We investigated role striatal DR1/PKA/P-tau signal transduction molecular event underlying...
The contents of 18 free amino acids in 87 Chinese honey samples from four botanical origins (linden, acacia, vitex and rape) were determined by developing a high-performance liquid chromatography with fluorescence detector (HPLC-FLD) method an in-loop automated pre-column derivatization. acid profiles these used to construct statistical model distinguish honeys various floral origins.The average all linden lower than the other three types honey. Phenylalanine was particularly useful present...
As essential calcium ion (Ca2+) sensors in plants, calcium-dependent protein kinases (CDPKs) function regulating the environmental adaptation of plants. However, response mechanism CDPKs to salt stress is not well understood. In current study, wheat salt-responsive gene TaCDPK27 was identified. The open reading frame (ORF) 1875 bp, coding 624 amino acids. predicted molecular weight and isoelectric point were 68.905 kDa 5.6, respectively. has closest relationship with subgroup III members...
This study aimed to explore the relationship between Sirtuin 3 (SIRT3) gene and endothelial cell dysfunction, contributing progression of coronary atherosclerosis driven by hyperglycemia.We measured serum SIRT3 levels using enzyme-linked immunosorbent assay in 95 patients with type 2 diabetes mellitus (T2DM) who underwent diagnostic angiography. The were divided into two groups according presence (n = 45) or absence 50) artery disease (CAD). Human aortic cells (HAECs) grown vitro a medium...
Arsenic is known to be a human carcinogen as well one of the most effective drugs for treatment patients with acute promyelocytic leukemia. The intermediate metabolites arsenic, monomethylarsonous acid (MMA(III)) and dimethylarsinous (DMA(III)), are formed by methylation reactions, they more reactive toxic than inorganic precursor arsenite (iAs(III)); however, detailed mechanism toxicity poorly understood. Here, we studied effects three arsenic compounds (i.e., iAs(III), MMA(III), DMA(III))...
<b><i>Background/Aims:</i></b> Free radical scavenger tempol is a protective antioxidant against ischemic injury. Tubular epithelial apoptosis one of the main changes in renal ischemia/reperfusion (I/R) Meanwhile some proteins related with and inflammation are also involved I/R We tested hypothesis that protects injury by activating protein kinase B/mammalian target rapamycin (PKB, Akt/mTOR) glycogen synthase 3β (GSK3β) pathways as well coordinating proteins....
Objective To assess the efficacy and safety of iguratimod in adult patients with active axial spondyloarthritis (axSpA).
Arsenic trioxide (As2O3) has been recently established as one of the most effective drugs for treatment patients with acute promyelocytic leukemia. However, it exhibited to be less efficient non-promyelocytic leukaemia or other types malignant tumors. The purpose present study was explore new therapeutic strategies based on As2O3 human multiple myeloma. Here, we first report cryptotanshinone (CPT) and synergy enhanced cytotoxicity in myeloma U266 cells. In particular, apoptosis related...
The purpose of this paper is to apply the decoupling index combined with LMDI method analyze contribution factors which influence electricity consumption in China over period 1991-2009. main results are as follows: (1) Electricity has been rising year by economic growth. came 427.37 Mtce 2009, accounted for 19.56% total energy consumption. (2) China’s intensity continuously decreased during 1990s and early 2000s, decreasing trend reserved since 2003. (3) activity effect most important...
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by extensive immune response, including over-activation of T and B cell development pathogenic autoantibodies, organ damage induced the formation deposition complex abnormal elevation type I interferon. Semaphorin5A (Sema5A) involved essentially in regulation also implicated pathogenesis disorders. We aimed to evaluate role Sema5A patients with SLE. Serum levels were tested enzyme-linked immunosorbent assay (ELISA) 152...