A5100662698- Optical Imaging and Spectroscopy Techniques
- Autoimmune Neurological Disorders and Treatments
- Surgical Simulation and Training
- Genetics and Neurodevelopmental Disorders
- Non-Invasive Vital Sign Monitoring
- Prostate Cancer Treatment and Research
- Ginkgo biloba and Cashew Applications
- Chronic Kidney Disease and Diabetes
- Glioma Diagnosis and Treatment
- Bacterial Infections and Vaccines
- Hemodynamic Monitoring and Therapy
- Peripheral Neuropathies and Disorders
- Infectious Encephalopathies and Encephalitis
- Immunodeficiency and Autoimmune Disorders
- Air Quality and Health Impacts
- Neurological Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Functional Brain Connectivity Studies
- Viral Infections and Immunology Research
- Cerebrovascular and genetic disorders
- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Whipple's Disease and Interleukins
- Heat shock proteins research
- Cancer, Hypoxia, and Metabolism
Wichita State University
2025
Guangzhou Medical University
2015-2025
First Affiliated Hospital of Hebei Medical University
2025
Hebei Medical University
2025
Boston University
2022-2025
Yichang Central People's Hospital
2024
Stanford University
2023-2024
Guangzhou Women and Children Medical Center
2014-2023
Shaanxi Normal University
2005-2023
Wenzhou Medical University
2023
The aim of the study was to evaluate predictive value preoperative high-sensitive C-reactive protein/albumin (hs-CRP/Alb) ratio in systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PCNL).We retrospectively reviewed 556 patients who underwent PCNL at our institution between August 2015 and February 2018. primary endpoint for development SIRS operation. A univariate multivariate logistic regression analysis used identify independent factors associated with...
Objective This work aims to study the clinical features and risk factors of children with bacterial meningitis (BM) in southern China. Methods Clinical data BM between 2012 2018 from one national center were analyzed retrospectively. Results A total 838 patients (male/female = 1.8:1) enrolled, 90.6% under 1 year old. Common symptoms included fever, seizure, lethargy, vomiting, anorexia, poor feeding, irritability. Most initially exhibited typical cerebrospinal fluid (CSF) changes BM,...
To investigate the hemodynamic differences in various brain regions between alcohol dependence (AlcD) patients and healthy controls during a verbal fluency task (VFT) using functional near-infrared spectroscopy (fNIRS), to further explore clinical predictive value of fNIRS before therapy for outcome relapse AlcD after 3 months. A retrospective survey was conducted on 123 149 same period. Baseline assessment performed analyze two groups different regions. During hospitalization, underwent...
Neuroscience of the everyday world requires continuous mobile brain imaging in real time and ecologically valid environments, which aids directly translating research for human benefit. Combined functional near-infrared spectroscopy (fNIRS) electroencephalography (EEG) studies have increased demand, as combined systems can provide great insights into cortical hemodynamics, neuronal activity, neurovascular coupling. However, fNIRS-EEG remain limited modularity portability due to restrictions...
In this study, the immunogenic and structural properties of ovalbumin (OVA) induced by pulsed electric fields (PEF) treatment were investigated. The estimated IgG IgE binding abilities, which determined enzyme-linked immunosorbent assay (ELISA) using rabbit polyclonal antibodies egg-allergy patients' sera, respectively. changes monitored circular dichroism (CD), ultraviolet absorption, fluorescence spectroscopy. When OVA samples treated at low field intensity (below 25 kV/cm, for 180 μs) or...
Significance: Functional near-infrared spectroscopy (fNIRS), a well-established neuroimaging technique, enables monitoring cortical activation while subjects are unconstrained. However, motion artifact is common type of noise that can hamper the interpretation fNIRS data. Current methods have been proposed to mitigate artifacts in data still dependent on expert-based knowledge and post hoc tuning parameters. Aim: Here, we report deep learning method aims at removal from being assumption...
Currently, there is a dearth of objective metrics for assessing bi-manual motor skills, which are critical high-stakes professions such as surgery. Recently, functional near-infrared spectroscopy (fNIRS) has been shown to be effective at classifying task types, can potentially used performance level. In this work, we use fNIRS data predicting the scores in standardized surgical certification and propose deep-learning framework 'Brain-NET' extract features from data. Our results demonstrate...
SignificanceAdvances in electronics have allowed the recent development of compact, high channel count time domain functional near-infrared spectroscopy (TD-fNIRS) systems. Temporal moment analysis has been proposed for increased brain sensitivity due to depth selectivity higher order temporal moments. We propose a general linear model (GLM) incorporating TD data and auxiliary physiological measurements, such as short separation channels, improve recovery HRF.AimsWe compare performance...
Relevant studies have recognized the important role of hepatic stellate cell (HSC) senescence in anti-liver fibrosis. Cellular is believed to be regulated by cGAS-STING signaling pathway. However, underlying exact mechanisms pathway are still unclear. Here, we found that Oroxylin A could promote HSC activating Moreover, activation was dependent on DNMT3A downregulation, which suppressed cGAS gene DNA methylation. Interestingly, attenuation DNMT activity relied reduction methyl donor SAM...
To investigate the efficacy of rituximab in treatment idiopathic membranous nephropathy (IMN).A total 77 patients with IMN diagnosed both our hospital and other hospitals were included this study; divided into two groups: a treatment-naïve group (n = 19) refractory/relapsed 58). The clinical data patients, including urine examination, blood test, safety evaluation results, analysed retrospectively. changes biochemical indexes adverse reactions compared between groups before after treatment,...
Acquisition of fine motor skills is a time-consuming process as it based on learning via frequent repetitions. Transcranial electrical stimulation (tES) promising means enhancing simple skill development neuromodulatory mechanisms. Here, we report that non-invasive neurostimulation facilitates the complex bimanual associated with surgical task. During training 12 medical students Fundamentals Laparoscopic Surgery (FLS) pattern cutting task over period days, observed transcranial direct...
Abstract Pathological remodeling characterized by extracellular matrix (ECM) accumulation contributes to diabetic nephropathy (DN). This study evaluated the effects of Ginkgo biloba extract (GbE) on metabolism ECM in rat mesangial cells cultured hyperglycemic conditions. The high glucose conditions were allotted into six groups: normal control group, low concentration GbE moderate and captopril group. In presence glucose, levels metalloproteinase‐2 (MMP‐2), metalloproteinase‐9 (MMP‐9)...
Significance: Surgical simulators, both virtual and physical, are increasingly used as training tools for teaching assessing surgical technical skills. However, the metrics assessment in these simulation environments often subjective inconsistent. Aim: We propose functional activation metrics, derived from brain imaging measurements, to objectively assess correspondence between with motor skills subjects varying degrees of skill. Approach: Cortical based on changes oxygenated hemoglobin...
Early life exposure to organophosphate (OP) pesticides has been linked with poorer neurodevelopment from infancy adolescence. In our Center for the Health Assessment of Mothers and Children Salinas (CHAMACOS) birth cohort, we previously reported that residential proximity OP use during pregnancy was associated altered cortical activation using functional near infrared spectroscopy (fNIRS) in a small subset (n = 95) participants at age 16 years.