A5089671535- Multi-Criteria Decision Making
- Organ Transplantation Techniques and Outcomes
- Risk and Safety Analysis
- Aviation Industry Analysis and Trends
- Business and Management Studies
- Fuzzy Logic and Control Systems
- Environmental Sustainability and Education
- Xenotransplantation and immune response
- Fuzzy Systems and Optimization
- Renal Transplantation Outcomes and Treatments
- Science and Education Research
- Air Traffic Management and Optimization
- Liver Disease and Transplantation
- Chemistry Education and Research
- Education and Digital Technologies
- Transplantation: Methods and Outcomes
- Vehicle Routing Optimization Methods
- Microbial Community Ecology and Physiology
- Advanced Manufacturing and Logistics Optimization
- Agricultural and Food Sciences
- Transportation Planning and Optimization
- Optimization and Mathematical Programming
- Occupational Health and Safety Research
- Rural Development and Agriculture
- Solar Radiation and Photovoltaics
Universidade Federal do Rio de Janeiro
2016-2025
Federal Center for Technological Education Celso Suckow da Fonseca
2024
Instituto Federal do Maranhão
2024
Universidade Federal de Santa Catarina
2024
Fuzzy Systems Institute
2024
University of Cambridge
2019
Centro de Tecnologia Mineral
2016-2017
Massachusetts Institute of Technology
2016
Universidade Federal do Paraná
2016
Instituto de Pesquisas Jardim Botânico do Rio de Janeiro
2016
A 26-year-old female patient with fulminant hepatic failure and a history of autoimmune hepatitis was heterotopically transplanted pig xenograft to provide temporary metabolic support prior transplantation human donor organ. Circulating natural antipig antibodies were removed by plasmapheresis ex vivo en bloc perfusion the kidneys. The liver functioned after as measured active bile production, stabilization prothrombin levels, reduction in circulating levels lactic acid enzymes AST ALT....
Um estudo transversal foi realizado em uma comunidade agrícola localizada Nova Friburgo, RJ, para conhecer os aspectos epidemiológicos, clínicos e laboratoriais da exposição múltipla a agrotóxicos amostra representativa de 102 pequenos agricultores, ambos sexos. Os trabalhadores foram submetidos um extenso protocolo que incluía aplicação questionário ocupacional, coleta amostras biológicas exame toxicológico avaliação clínica - geral neurológica. resultados dos exames toxicológicos revelaram...
Cyanobacteria of the genus Synechococcus are major contributors to global primary productivity and found in a wide range aquatic ecosystems. This collective (SC) is metabolically diverse, with some lineages thriving polar nutrient-rich locations others tropical or riverine waters. Although many studies have discussed ecology evolution SC, there paucity knowledge on its taxonomic structure. Thus, we present new classification framework for SC based recent advances microbial genomic taxonomy....
The article analyzes the relevance of digital social networks in field Information Science, analyzing their impacts on other spheres society. In addition to being spaces for interaction and content production, these platforms exert significant influence dissemination information construction contemporary narratives. However, breadth reach also make them susceptible spread disinformation fake news. research explores fundamental concepts such as Cognitive warfare, hybrid narrative highlighting...
Background. A study was performed by 17 different U.S. liver transplantation centers to determine the safety and efficacy of conversion from cyclosporine tacrolimus for chronic allograft rejection. Methods. Ninety-one patients were converted a mean 319 days after transplantation. The indication ongoing rejection confirmed biochemical histologic criteria. Patients followed 251 until end study. Results. Sixty-four (70.3%) alive with their initial hepatic at conclusion period defined as...
We have examined the nature of binding human xenoantibodies to pig liver and kidney vascular endothelium. Our results demonstrate that serum contains IgM IgG bind endothelium, pattern antibody is similar for both livers kidneys. Immunohistochemical analysis kidneys after perfusion with blood demonstrated xenoantibodies, complement (C3), fibrinogen glomerular An ELISA assay perfusate 500 ml through a single 60 min significant reduction in amount (67%) (55%) aortic Similar experiments...
Brequinar sodium (BQR) is a new immunosuppressive drug that highly effective in preventing graft rejection several different experimental settings, including primary allografts and xenografts. A short course of BQR treatment during the onset allograft can induce permanent survival liver kidney rats. To study molecular basis BQR-induced prolongation survival, we analyzed intragraft pattern IL-1 alpha, IL-2, IL-2R, IL-4, IL-6, IL-10, TNF gene expression ACI-to-LEW model. semiquantitative...
Human-to-pig xenoantibodies may constitute a major obstacle to the successful use of pigs as xenograft donors for human transplantation. Our studies demonstrate that normal serum contains antibodies, primarily IgM, are cytotoxic pig aortic endothelial cells (PAECs). These antibodies bind several antigens isolated from PAECs, lymphocytes, platelets, red blood cells, and kidney. Absorption with lymphocytes removes activity PAECs some, but not all, IgM capable binding in an ELISA assay PAECs....
Lipid peroxidation may play a major role in the loss of liver graft viability after prolonged cold ischemia and reperfusion injury. The lazaroid compound U74006F is potent inhibitor lipid peroxidation, this study was designed to evaluate efficacy preventing ischemia–reperfusion damage three different models: pig endothelial cells culture, ex vivo isolated perfusion orthotopic transplantation syngeneic rat livers. addition University Wisconsin preservation solution significantly cell 48 72 hr...
Abstract Few classic models put forward mathematical tools and operational rules that are sufficiently flexible consistent to contribute regional development policy. The discussed in this work form part of a group structured based on potentialities used organize economic spaces. These essentially formed by the elements two matrices: one matrix whose represent factors demanded industries another supplied geographic zones. first three linear fourth model – proposal employs an algorithm theory...
Increased worldwide travel and immigration have led to an increase in the incidence of hepatic hydatid disease outside endemic areas. In nonendemic areas lack familiarity with may lead a delay diagnosis increased risk for development complicated disease. Complicated is defined as: infected cysts, cysts hyperechoic solid pattern or calcified walls, biliary rupture. Over 6-month period six patients were referred our institution. All immigrants from found including cholangitis intrabiliary...
Recurrent pyogenic cholangitis (RPC) is a chronic disease with multiple exacerbations requiring repeated biliary dilatation and stone removal. Even after adequate drainage, most patients will have progression of intrahepatic disease. Management RPC multidisciplinary challenge for endoscopists, interventional radiologists, surgeons because the frequency inaccessibility strictures stones. Complete clearance at any one operation difficult. Hepaticojejunostomy subcutaneous afferent limb safe...