Yangyang Wang

ORCID: 0000-0002-3024-305X
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About
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Research Areas
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Cancer Research and Treatments
  • Antibiotic Resistance in Bacteria
  • Advanced biosensing and bioanalysis techniques
  • Heavy metals in environment
  • Glycosylation and Glycoproteins Research
  • Advanced Photocatalysis Techniques
  • Immunotherapy and Immune Responses
  • Genomics and Phylogenetic Studies
  • Metabolomics and Mass Spectrometry Studies
  • Electrochemical sensors and biosensors
  • Cancer, Hypoxia, and Metabolism
  • Cancer Mechanisms and Therapy
  • Listeria monocytogenes in Food Safety
  • Cancer Cells and Metastasis
  • Cancer Immunotherapy and Biomarkers
  • Protein Hydrolysis and Bioactive Peptides
  • Smart Materials for Construction
  • Microbial bioremediation and biosurfactants
  • Advanced Biosensing Techniques and Applications
  • Circular RNAs in diseases
  • Biochemical and Structural Characterization
  • FOXO transcription factor regulation
  • Bacterial biofilms and quorum sensing
  • Wastewater Treatment and Nitrogen Removal

Henan Provincial People's Hospital
2020-2024

Zhengzhou University
2020-2024

Henan Agricultural University
2020-2024

Smiths Detection (United States)
2022-2024

University of Shanghai for Science and Technology
2024

Henan University
2024

University of Jinan
2023-2024

Zhejiang Gongshang University
2023

Changchun University of Technology
2023

Shenzhen Polytechnic
2023

Some evidence suggests that bone health can be regulated by gut microbiota. To better understand this, we performed 16S ribosomal RNA sequencing to analyze the intestinal microbial diversity in primary osteoporosis (OP) patients, osteopenia (ON) patients and normal controls (NC). We observed an inverse correlation between number of bacterial taxa value mineral density. The estimators OP ON groups were increased compared with those NC group. Beta analyses based on hierarchical clustering...

10.7717/peerj.3450 article EN cc-by PeerJ 2017-06-15

Heavy metal pollution caused by a large number of abandoned industrial sites cannot be underestimated, but its human health risks have not been accurately assessed. This study investigated the heavy metals in soils typical southeastern China. Based on bioaccessibility different (Pb, Ni, Cu, Zn, Cd, Cr) soils, were evaluated, and controlling factors quantitatively The results showed that each had high degree spatial heterogeneity. Among them, Cd was most susceptible to relevant discrete input...

10.1016/j.ecoenv.2023.114870 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2023-04-08

Repeated sevoflurane exposure in neonatal mice can leads to neuronal apoptosis and mitochondrial dysfunction. The mitochondria are responsible for energy production maintain homeostasis the central nervous system. mitochondria-associated endoplasmic reticulum membrane (MAM) is located between (ER), it critical function cell survival. MAM malfunction contributes neurodegeneration, however, whether involved sevoflurane-induced neurotoxicity remains unknown. Our study demonstrated that repeated...

10.1016/j.expneurol.2024.114807 article EN cc-by-nc Experimental Neurology 2024-05-03

// Francesco Sabbatino 1,3,4,* , Yangyang Wang 1,3,* Xinhui 1,3 Keith T. Flaherty 2,3 Ling Yu 5,7 David Pepin Giosue' Scognamiglio 5,8 Stefano Pepe 4,10 John M. Kirkwood 6 Zachary A. Cooper 1,3,9 Dennie Frederick Jennifer Wargo Soldano Ferrone Cristina R. 1 Department of Surgery, Massachusetts General Hospital, Boston, MA 2 Medical Oncology, 3 Harvard School, 4 Clinical and Molecular Oncology Endocrinology, University Naples "Federico II", Naples, Italy 5 Pittsburgh Cancer Institute,...

10.18632/oncotarget.1878 article EN Oncotarget 2014-03-31

With the widespread application of internet big data, accurate Medical outpatient data prediction is crucial for improving efficiency medical management systems and optimizing resource allocation. This study focuses on rehabilitation medicine ward a certain hospital over past five years, selecting date, number patients, total drug revenue, daily income as basic input data. After multiprocessing, an ARIMA time series model established to predict fill part ward. At same time, under premise ADF...

10.54097/dryhv286 article EN cc-by-nc Deleted Journal 2025-02-24

 Toxic metal content testing, environmental magnetic monitoring and in vitro bioaccessibility experiments each have their own advantages are often used independently for monitoring, but there few studies that combine the three to evaluate hazards of toxic metals humans. This paper investigated total content, properties nine potentially elements (Zn, Sn, Pb, Cu, Fe, Ni, Cr, Sr, Mn) dustfall from different functional zones Shanghai, China, systematically compared related results. The...

10.5194/egusphere-egu25-10426 preprint EN 2025-03-14

The molecular mechanisms responsible for angiogenesis and abnormal expression of angiogenic factors in gastric cancer, including vascular endothelial growth factor (VEGF), remain unclear. histone demethylase retinoblastoma binding protein 2 (RBP2) is involved tumorgenesis by inhibiting the cyclin-dependent kinase inhibitors (CDKIs).The RBP2, VEGF, CD31, CD34 Ki67 was assessed 30 human cancer samples normal control samples. We used quantitative RT-PCR, western blot analysis, ELISA,...

10.1186/1476-4598-13-81 article EN cc-by Molecular Cancer 2014-04-09

The aim of the present study was to screen novel dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from Macadamia integrifolia antimicrobial protein 2 (MiAMP2) and evaluate potential antidiabetic targets involved signaling pathways using in silico approaches. In digestion MiAMP2 with pepsin, trypsin chymotrypsin performed ExPASy PeptideCutter generated were subjected BIOPEP-UWM, iDrug, INNOVAGEN Autodock Vina for further analyses. Six EQVR, EQVK, AESE, EEDNK, EECK, EVEE predicted possess...

10.1016/j.crfs.2021.08.008 article EN cc-by-nc-nd Current Research in Food Science 2021-01-01

Herein, a flexible near-infrared (NIR) light-actuated photoelectrochemical (PEC) lab-on-paper device was constructed toward miRNA-122 detection, utilizing the combination of DNA-programmed NaYF4/Yb,Tm upconversion nanoparticles (UCNPs) and Z-scheme AgI/WO3 heterojunction grown in situ on gold nanoparticle-decorated 3D cellulose fibers. The UCNPs were employed as light transducers for converting NIR into ultraviolet/visible (UV/vis) to excite nanojunction. multiple diffraction matched...

10.1021/acsami.3c16328 article EN ACS Applied Materials & Interfaces 2024-02-01

// Yangyang Wang 1, * , Jiping Zeng 2, Jianyong Pan 3 Xue Geng 1 Lupeng Li 2 Jing Wu Ping Song Ying Jilan Liu Lixiang Department of Pharmacology, Shandong University School Medicine, Jinan 250012, P.R.China Biochemistry and Molecular Biology, P.R. China Hepatobiliary Surgery, Qilu Hospital University, These authors have contributed equally to this work Correspondence to: Wang, email: wanglx@sdu.edu.cn Keywords: miR-320a, FoxM1, proliferation, gastric cancer, P27 KIP1 Received: December 06,...

10.18632/oncotarget.8676 article EN Oncotarget 2016-04-11

Abstract The reflectance of wheat’s canopy exhibits angular sensitivity, which can influence the accuracy different methods for its leaf area index (LAI) estimation through multi-angular remote sensing. primary objective this study was to assess and compare ability various LAI from 13 view zenith angles (VZAs). four included: (1) common hyper-spectral vegetation indices (VIs), (2) optimal two-band combination VIs (i.e., VIs: normalized difference index, simple ratio index), (3)...

10.1038/s41598-020-70951-w article EN cc-by Scientific Reports 2020-08-18

Dissemination of antibiotic resistance gene (ARG) is a huge challenge around the world. Natural organic matter (NOM) one most commonly components in aquatic systems. Information regarding ARG transfer induced by NOM still lacking. In this study, experimental exploration and model prediction on RP4 plasmid conjugative between bacteria under exposure was conducted. Compared with no exposure, frequency increased 7.1-fold 3.2-fold to 10 kDa 100 respectively. lower molecular weight higher...

10.1016/j.envint.2022.107653 article EN cc-by-nc-nd Environment International 2022-11-24

A novel carbendazim-degrading actinobacterium, designated djl-6-2(T), was isolated from the sludge of a carbendazim wastewater treatment facility in Jiangsu province, China. The morphological and chemotaxonomic properties isolate were typical members genus Rhodococcus. Strain djl-6-2(T) formed coherent cluster with Rhodococcus qingshengii djl-6(T), baikonurensis DSM 44587(T), erythropolis 43066(T) globerulus 43954(T) 16S rRNA gene sequence analysis. results DNA-DNA hybridization above...

10.1099/ijs.0.013219-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2009-11-03

Osteoporosis (OP) is a metabolic bone disorder characterized by low mass and deterioration of micro-architectural tissue. The most common type OP postmenopausal osteoporosis (PMOP), with fragility fractures becoming global burden for women. Recently, the gut microbiota has been connected to metabolism. aim this study was characterize signatures in PMOP patients controls. Fecal samples from 21 37 controls were collected analyzed using amplicon sequencing V3-V4 regions 16S rRNA gene. mineral...

10.3389/fmicb.2023.1113174 article EN cc-by Frontiers in Microbiology 2023-04-03
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