A5012506328- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Inflammatory Bowel Disease
- Helicobacter pylori-related gastroenterology studies
- Liver Disease and Transplantation
- Microscopic Colitis
- Gastrointestinal Tumor Research and Treatment
- Clinical Nutrition and Gastroenterology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Nutrition and Health in Aging
- Biliary and Gastrointestinal Fistulas
- Drug-Induced Hepatotoxicity and Protection
- Esophageal Cancer Research and Treatment
- Gallbladder and Bile Duct Disorders
- Esophageal and GI Pathology
- Apelin-related biomedical research
- Chronic Lymphocytic Leukemia Research
- Acute Lymphoblastic Leukemia research
- Amoebic Infections and Treatments
- Vascular Malformations and Hemangiomas
- Gastric Cancer Management and Outcomes
- Vitamin K Research Studies
Ege University
2015-2025
Janssen (United States)
2023
Fred Hutch Cancer Center
2023
Konya Eğitim ve Araştırma Hastanesi
2023
University of Turin
2023
Ege Üniversitesi Tıp Fakültesi Hastanesi
2018-2022
Izmir University
2022
University of Pittsburgh
2004-2010
Siriraj Hospital
2010
Mahidol University
2010
The aim of this study was to evaluate nutritional status and sarcopenia in patients with inflammatory bowel disease (IBD) clinical remission.A total 344 IBD remission were included cross-sectional study. Patients activity (Harvey-Bradshaw index >5 for Crohn's partial Mayo scores ≥5 ulcerative colitis) excluded. Sociodemographic, clinical, anthropometric data recorded. BMI categorized according WHO criteria. Nutritional assessed using the Mini Assessment (MNA) questionnaire. Body composition...
This study aimed to evaluate the diagnostic efficacy of cell block (CB) and liquid-based cytology (LBC) for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic tumors. The included patients who underwent EUS-FNA tumors between January 2015 February 2021 whose samples were both processed LBC CB. Data 390 (220 men, mean age: 64.2 ± 11.4 years) retrospectively analyzed. Of detected lesions (size: 17-120 mm; mean: 39.9 13.9 mm), 220 (56.4%) located head uncinate process...
Abstract Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease with remissions and flares. Approximately 20% of UC Patients develop acute severe ulcerative (ASUC), serious condition that refractory to standard therapies leads morbidity mortality. Rescue therapy (salvage therapy) steroids, cyclosporine, and/or infliximab recommended by guidelines.1 The colectomy rate in ASUC remains at around 36% even the biological millennium.2 Upadacitinib (UPA) JAK1 selective inhibitor...
Abstract Background Patient-reported outcome measures (PROMs) are used to assess the effectiveness of treatments received by patients in terms clinical response inflammatory bowel disease (IBD). We aimed evaluate perceived from patient’s perspective using PRO2, IBD Control Questionnaire (ICQ) and Visual Analogue Scale (VAS) at end induction therapy treated with upadacitinib. also correlation PROMs biochemical response. Methods included who underwent upadacitinib 01/07/2024 01/10/2024 ten...
Tumor necrosis factor alpha (TNF-alpha) has a central role in the pathogenesis of acute pancreatitis and related systemic complications. The aim this study is to investigate therapeutic effectiveness monoclonal TNF antibody (infliximab) edematous severe necrotizing models rats.One hundred rats were randomly divided into 10 groups. Acute (AEP) was induced by injection cerulein 20 microg/kg 4 times subcutaneously at hourly intervals. Severe (SNP) retrograde 3% taurocholate common...
Both C reactive protein (CRP) and procalcitonin (PCT) are well known acute phase reactant proteins. CRP was reported to increase in metabolic syndrome type-2 diabetes. Similarly altered level of serum PCT found chronic liver diseases cirrhosis. The is considered the main source a PCT, however, levels non-alcoholic fatty disease (NAFLD) were not compared previously. Therefore we aimed study diagnostic discriminative role NAFLD. Fifty NAFLD cases 50 healthy controls included study. Liver...
Pancreatic steatosis (PS) is a pathology associated with metabolic syndrome (MS), endocrin and exocrine disfunctions of the pancreas, fatty liver. The data on frequency PS are very limited. We aimed to evaluate detected by transabdominal ultrasonography (TAU) in gastroenterology clinics located different geographical regions Turkey factors it.
The diagnosis of an underlying myeloproliferative neoplasm (MPN) is often problematic in patients with Budd Chiari syndrome (BCS) or portal vein thrombosis (PVT). This study aimed to assess the diagnostic value JAK2 gene V617F gain-of-function mutation for MPN splanchnic patients.One hundred eleven (80 PVT, 27 BCS, and 4 BCS PVT) were investigated. control group included 56 volunteers without any known diseases. LightCycler SNP genotyping was performed detect DNA extracted from peripheral...
Abstract Post Endoscopic Retrograde Cholangiopancreatography (ERCP) pancreatitis is one of the most serious complications ERCP. Our study aims to investigate risk, predisposing factors and prognosis after ERCP in elderly patients. Patients referred unit between April 2008 2012 admitted hospital at least 1 day procedure were included study. Information including patient’s demographics, diagnosis, imaging findings, biochemical analysis, details recorded. The severity post (PEP) was determined...
Sleep disorders (SDs) are common in cirrhotics and often associated with hepatic encephalopathy. SDs negatively affect patients' daily activities work efficiency. For this reason, early diagnosis is important. The methods used for of not practical need longer periods application evaluation. In study, we aimed to investigate sleep related clinical parameters cirrhosis also wanted the using Timing Quality Screening questionnaire (STSQS), a simple form short time, its correlation Pittsburg...
This guideline was produced in connection with the World Digestive Health Day (WDHD) held 2016 on theme of "Diet and Gut." The Guideline Development Review Team consisted experts WDHD as well invited experts, including diet nutrition specialists, pharmacists, primary care physicians. Given central role digestive tract its related organs processes digestion absorption, it should come no surprise that food we eat has critical complex interactions gastrointestinal contents, microbiota. nature...
Abstract Background: Eradication rates of Helicobacter pylori have declined to unacceptable levels in recent years. New and effective treatment options are warranted both as a first second line treatment. Aim: To test an effectiveness modified sequential therapy with levofloxacin for H. eradication Turkey. Material Methods: infected dyspeptic patients were included the study. Subjects treated consisting rabeprazole 20 mg b.i.d. amoxicillin 1 g b.i.d., 7 days followed by b.i.d, 500 q.d....
Myasthenia gravis is an antibody-mediated autoimmune disease at the neuromuscular junctions. It can be associated with many other diseases. We report a case of acute presentation hepatitis myasthenia gravis, thymoma, Hashimoto thyroiditis and connective tissue disorder.
In this study we aimed to clarify the role of mast cells in development and progression inflammation cerulein-induced acute pancreatitis (AP) rats. We have also examined effects ketotifen; a mast-cell stabilizing agent treatment its relation with nitric oxide (NO) synthesis.In first part planned examine cell stabilization pancreatitis, while second was focused on examining between NO synthesis potential ketotifen AP. Wistar albino rats were randomly divided into 6 groups (n: 10). study, AP...
Momordica charantia L., known as bitter melon (BM), is a plant that belongs to the family Cucurbitaceae. Aims of this study are investigate anti-inflammatory effect crude BM extract on 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced experimental colitis model in rat. It was also aimed determine content and bioaccessibility carotenoids BM. purchased from local markets Izmir, Turkey. Fruits were lyophilized, powdered, used experiment. Carotenoids determined by high-performance liquid...
The aim of this study was to develop aprotinin-loaded microemulsion (MA) for intravenous administration and evaluate the biodistribution therapeutic potential developed formulation in acute pancreatitis models rats. Phase diagrams were constructed identify region optimal evaluated physicochemical properties treatment effect rats, comparisons made with solution aprotinin (SA). To drug by gamma scintigraphy radiolabeled 99mTc radionuclide. Mild severe induced rats subcutaneous injections...