A5102026539- Obstructive Sleep Apnea Research
- Inflammasome and immune disorders
- Esophageal and GI Pathology
- Sleep and related disorders
- Gastroesophageal reflux and treatments
- Neuroscience of respiration and sleep
- Breast Cancer Treatment Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Gut microbiota and health
- MRI in cancer diagnosis
- Plant Molecular Biology Research
- Pelvic floor disorders treatments
- Intestinal Malrotation and Obstruction Disorders
- Circadian rhythm and melatonin
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Gastrointestinal Tumor Research and Treatment
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Eosinophilic Esophagitis
- Pediatric Hepatobiliary Diseases and Treatments
- Colorectal Cancer Surgical Treatments
- Tuberculosis Research and Epidemiology
Central South University
2024-2025
Second Xiangya Hospital of Central South University
2024-2025
Chinese PLA General Hospital
2019-2024
Capital Medical University
2021-2023
Beijing Children’s Hospital
2021-2023
The Military General Hospital of Beijing PLA
2014
Dalian Medical University
2014
Abstract The central nervous system (CNS) is the most delicate in human body, with complex structure and function. It vulnerable to trauma, infection, neurodegeneration autoimmune diseases, activates immune system. An appropriate inflammatory response contributes defence against invading microbes, whereas an excessive can aggravate tissue damage. NLRP3 inflammasome was first one studied brain. Once primed activated, it completes assembly of (sensor NLRP3, adaptor ASC, effector caspase-1),...
Abstract Background Conventional methods of screening for Hirschsprung disease ( HD ) in newborns (barium enema, BE ; anorectal manometry, ARM rectal suction biopsy, RSB have limitations and/or are invasive. High‐resolution manometry HR ‐ is a minimally invasive technique that has potential to overcome most these limitations, but normative data and performance characteristics not been reported newborns. The aims our study were assess sphincter metrics including resting pressure RP ), anal...
We explored whether declarative memory consolidation is impaired in children with rapid eye movement sleep-related obstructive sleep apnea (REM-OSA) and investigated the correlation between respiratory parameters.
To analyze the clinical and polysomnographic characteristics in children with mild OSA respiratory events terminated predominantly arousal.Children aged 3-10 yrs who had obstructive sleep apnea (OSA) were enrolled. All underwent polysomnography, patients' data collected by using sleep-related breathing disorders (SRBD) questionnaire OSA-18 quality of life questionnaire.In total, five hundred seventy-seven eligible. Children arousal predominant group younger showed a lower rate male obesity....
The increasing incidence of childhood obesity annually has led to a surge in physical and mental health risks, making it significant global public concern. This study aimed discover novel biomarkers simple through integrative multi-omics analysis, uncovering their potential connections providing fresh research directions for the complex pathogenesis treatment strategies. Transcriptome, untargeted metabolome, 16 S rDNA sequencing were conducted on subjects examine transcripts, metabolites...
The purpose of this study was to evaluate the feasibility a simple method named aspiration and coagulation (AC) for reducing risk postoperative bleeding after gastric endoscopic submucosal dissection (ESD).
Abstract Background Achalasia is a rare primary esophageal motility disorder disease. It reported that the long-term effect of fully coated anti-reflux metal stent (FCARMS) implantation satisfactory. Operated by skilled and experienced endoscopist, per-oral endoscopic myotomy (POEM) treatment equivalent to surgical myotomy. So far, there still few evidence prove FCARMS or POEM which better for achalasia. The choice achalasia controversial. aim this study find more suitable therapy comparing...
Objective: To compare the long-term outcomes after focused ultrasound ablation surgery (FUAS) versus myomectomy for uterine fibroids. Methods: A retrospective study was conducted on women who were treated by FUAS or fibroids at First Medical Center of Chinese PLA General Hospital from January 2007 to 2015. Regular follow-up evaluate symptoms relief, recurrence, need re-interventions and complications two groups. Results: The effective rates 95.7% (730/763) 95.5% (1 151/1 205) in myomectomy,...
Abstract Background The population characteristics of Inflammatory Bowel Disease (IBD) in China are different from those western countries, and this lacks large sample clinical data. This study aimed to analyze the inpatients with severe complications IBD our center. Methods In study, medical records 510 hospitalized patients (excluding pediatrics) were included, digestive tract perforation, massive hemorrhage, thrombosis, toxic megacolon, fistula, stenosis, malnutrition, infection,...
Abstract Background : Achalasia is a rare primary esophageal motility disorder disease. It reported that the long-term effect of fully coated anti-reflux metal stent (FCARMS) implantation satisfactory. Operated by skilled and experienced endoscopist, POEM treatment equivalent to surgical myotomy. So far, there still few evidence prove or which better for achalasia. The choice achalasia controversial. Therefore, aim this study find more suitable therapy comparing efficacy FCARMS POEM. Methods...