- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Eosinophilic Esophagitis
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Biliary and Gastrointestinal Fistulas
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Veterinary medicine and infectious diseases
- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal motility and disorders
- Galectins and Cancer Biology
- Abdominal vascular conditions and treatments
- Systemic Sclerosis and Related Diseases
- Helminth infection and control
Kaohsiung Veterans General Hospital
2009-2018
National Yang Ming Chiao Tung University
2009-2018
National Taipei University
2012-2018
National Yang Ming University Hospital
2006-2012
Taipei Veterans General Hospital
1991-2009
Fooyin University
2007
I-Shou University
2007
St. Martin de Porres Hospital
2006
Zero to Three
2002
Bridge University
2000
We conducted a prospective, randomized trial comparing sclerotherapy and ligation in 120 patients with acute bleeding of esophageal varices. All the were cirrhotic, 59 received sclerotherapy, 61 ligation. Treatment was repeated regularly until varices obliterated. The mean follow-up period 295 ± days 310 105 for groups, respectively. control active 12/15 (80%) group 18/19 (94%) ( P = .23). numbers treatment sessions required to achieve variceal obliteration 6.5 1.2 3.8 0.4 < .001)....
Thirty-nine patients admitted during a 16-month period for acute bleeding from varices confirmed by emergency endoscopy were randomized to receive either continuous intravenous infusions of vasopressin alone (0.66 units per min) (Group I: 19 patients) or plus sublingual nitroglycerin (0.6 mg every 30 min 6 hr) II: 20 patients). The two groups similar in the type and severity their cirrhosis. Bleeding was controlled initially 47% (9/19) Group I 55% (11/20) II after hr infusion (not...
This prospective cohort study investigated the impact of Helicobacter pylori infection on development various gastric malignancies.We prospectively followed up 1,225 dyspeptic Taiwanese who had nonulcer dyspepsia, ulcers, or duodenal ulcers at enrollment. Among them, 618 (50.4%) H. and 607 (49.6%) did not. Patients underwent endoscopy enrollment 1- to 3-yr intervals thereafter.During a mean follow-up 6.3 yr, adenocarcinoma developed in 7 pylori-infected patients, but none uninfected patients...
Both medical therapy and endoscopic variceal ligation (EVL) have proven to be comparable in the prevention of rebleeding. However, long-term results are still lacking. Our previous study enrolled 121 patients with history esophageal bleeding randomized receive EVL (EVL group, 60 patients) or drug therapy, nadolol plus isosorbide-5-mononitrate (N+I) (N+I 61 prevent The group received regularly until obliteration. N+I during period. Patients were followed for up 8 years. After a median...
Environmental factors such as food, lifestyle and prevalence of Helicobacter pylori infection are widely different in Asian countries compared with the West, physiological functions genetic Asians may also be from those Westerners. Establishing an consensus for functional dyspepsia is crucial order to attract attention data countries, articulate experience views experts, provide a relevant guide on management primary care physicians working Asia.Consensus team members were selected experts...
ABSTRACT With the rising prevalence of antimicrobial resistance, failure rate standard triple therapy for Helicobacter pylori infection is increasing. Sequential and concomitant have been recommended to replace H. eradication in regions with high clarithromycin resistance. The aim this prospective, randomized, controlled study was simultaneously assess efficacies 10-day sequential 7-day therapies versus a treating infection. Consecutive -infected subjects were randomly assigned...
The prevalence of antibody to hepatitis C virus among Chinese subjects in Taiwan was evaluated using a commercially available enzyme immunoassay. overall 0.28% 1,419 healthy subjects, 0.8% 500 unselected paid blood donors and 0.4% 793 pregnant women. three offspring the mothers positive for were all found be at birth but became negative by age 6 mo. Among none 1,000 school children young adolescents had virus. patients selected "high-risk" groups, detected 100% 9 hemophiliac who human...
Endoscopic variceal ligation (EVL) is a new technique designed to manage esophageal varices. The effect of sclerotherapy following repeated banding remains unknown. Seventy-two patients with history bleeding received regular EVL until disappearance or left residual small Subsequently, were randomized receive (Group 1, 37 patients) serve as control 2, 35 patients). Group 1 one two sessions low-dose achieve complete disappearance. After mean follow-up 2 years, 4 months, recurrent varices...
Lethal pancreatitis has been reported after treatment for common bile duct stones using small endoscopic papillary balloon dilation.We retrospectively evaluated the safety and efficacy of large dilation alone without use sphincterotomy in Kaohsiung Veterans General Hospital. Success rate stone clearance, procedure-related adverse events incidents, frequency mechanical lithotripsy use, recurrent were recorded.A total 247 patients reviewed current study. The mean age was 71.2 years. Most them...
Background: Although the eradication of Helicobacter pylori infection benefits patients with gastric or duodenal ulcers, value eradicating in functional dyspepsia (FD) remains controversial. Aims: To determine whether H. can prevent subsequent development ulcers relieve symptoms patients. Methods: In a double‐blind, placebo‐controlled trial, 161 infected who had were randomly assigned to 7 days treatment lansoprazole‐based triple therapy placebo and then followed for 1 year. The main outcome...
Abstract Background : From October 1990 to January 1999, 11 of 2237 hepatoma patients at our hospital had gastrointestinal tract metastasis. We describe the radiological and endoscopic features, clinical course prognoses those patients. Methods All were male. Six hepatitis B carriers, cirrhosis was noted in eight on admission. reviewed all available radiological, pathological features. Results The commonest presentation frank bleeding. Histological proof involvement seen six Endoscopic...
This study investigated the genetic diversity of cag pathogenicity island (PAI) in Helicobacter pylori (H. pylori) relation to clinical outcome and interleukin (IL)-8 production.Seven genes PAI (cagA, cagE, cagG, cagM, cagT, open reading frame 13 10) were examined by polymerase chain reaction Southern blot hybridization using H. from 120 patients with different presentations (duodenal ulcer, gastric cancer, gastritis alone). IL-8 production AGS cells (gastric cancer cell line) cocultured was...
OBJECTIVE. Our purpose was to evaluate the safety and therapeutic efficacy of single-session prolonged alcohol sclerotherapy in treating large hepatic cysts. A comparison between 4-hour 2-hour retention techniques also studied.
Antibiotic resistance to amoxicillin in second-line eradication therapy for Helicobacter pylori infection is much less frequent than metronidazole. We conducted a randomized, controlled study compare the efficacies of standard quadruple rescue and new with replacing metronidazole patients failing first-line treatment. randomly assigned 120 who failed H. using proton pump inhibitor plus clarithromycin undergo 1-week esomeprazole, bismuth subcitrate, tetracycline either (EBTM group, n = 62) or...
Background Nucleos(t)ide analogues reduce the incidence of hepatitis B virus (HBV) reactivation in cancer patients undergoing systemic cytotoxic chemotherapy but experience solid tumors remains limited. Aims. The aim this study was to compare efficacy entecavir and lamivudine prophylaxis HBV tumor chemotherapy. Methods HBsAg seropositive for with prophylactic between January 2006 June 2013 were retrospectively investigated. outcome analyzed. risk factors examined. Results A total 213...
Warfarin reduces the incidence of thromboembolism but increases risk gastrointestinal bleeding (GIB). GIB during warfarin anticoagulation is rarely evaluated in Asian patients. This study aimed at investigating incidence, factors, management, and outcome Taiwanese patients treated with warfarin. We analyzed a cohort anticoagulated between July 1993 May 2012. Clinical data were retrieved chart-reviewing manner. A total 401 enrolled. The was 3.9% per patient-years. Multivariate analysis Cox...