A5087221607- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Esophageal and GI Pathology
- Congenital gastrointestinal and neural anomalies
- Infant Health and Development
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Complementary and Alternative Medicine Studies
- Colorectal Cancer Screening and Detection
- Liver Disease and Transplantation
- Esophageal Cancer Research and Treatment
- Pathogenesis and Treatment of Hiccups
- Gastrointestinal Tumor Research and Treatment
- Diet and metabolism studies
- Microscopic Colitis
- Gut microbiota and health
- Hepatitis C virus research
- Inflammatory mediators and NSAID effects
- Gastrointestinal Bleeding Diagnosis and Treatment
- Inflammatory Bowel Disease
- Neuropeptides and Animal Physiology
- Radiomics and Machine Learning in Medical Imaging
Taipei Veterans General Hospital
2016-2025
National Yang Ming Chiao Tung University
2016-2025
National Yang Ming University Hospital
2010-2019
Taipei Medical University
2013
National Taipei University
2012
National Taiwan University Hospital
2012
Korea Institute of Brain Science
2001-2012
Taipei Institute of Pathology
2011
National Central University
2010
University Gastroenterology
2003-2009
Other SectionsAbstractIntroductionPathophysiologyEtiology of Persistent and Intractable HiccupsConclusionFigureTableReferences
Hiroto Miwa, Uday C Ghoshal, Sutep Gonlachanvit, Kok-Ann Gwee, Tiing-Leong Ang, Full-Young Chang, Kwong Ming Fock, Michio Hongo, Xiaohua Hou, Udom Kachintorn, Meiyun Ke, Kwok-Hung Lai, Kwang Jae Lee, Ching-Liang Lu, Sanjiv Mahadeva, Soichiro Miura, Hyojin Park, Poong-Lyul Rhee, Kentaro Sugano, Ratha-korn Vilaichone, Benjamin CY Wong and Young-Tae Bak. J Neurogastroenterol Motil 2012;18:150-68. https://doi.org/10.5056/jnm.2012.18.2.150
Statin use decreases the risk of decompensation and mortality in patients with cirrhosis due to hepatitis C virus (HCV). Whether this beneficial effect can be extended general population or other causes, such as B (HBV) infection alcohol, remains unknown. also hepatocellular carcinoma (HCC) chronic HBV HCV infection. It is unclear whether observed pre-existing cirrhosis. The goal study was determine statin on rates decompensation, mortality, HCC HBV-, HCV-, alcohol-related Patients were...
Abstract Background and Aims: Hepatic steatosis is a histological characteristic in patients with chronic hepatitis C virus (HCV) infection. The aim of this study was to evaluate the prevalence hepatic Chinese C, look for possible correlation various histopathological changes clinical pathologic variables. Methods: One hundred six were enrolled, alcoholism or diabetes mellitus excluded. Clinical, biochemical virologic data, including HCV genotype serum HCV‐RNA titer findings, compared...
Environmental factors such as food, lifestyle and prevalence of Helicobacter pylori infection are widely different in Asian countries compared with the West, physiological functions genetic Asians may also be from those Westerners. Establishing an consensus for functional dyspepsia is crucial order to attract attention data countries, articulate experience views experts, provide a relevant guide on management primary care physicians working Asia.Consensus team members were selected experts...
Summary IBS patients and controls achieve comparable placebo analgesia upon experimentally induced rectal pain. The during the visceral pain involves enhanced brain activities relating to affect/cognition in patients. Placebo is a psychosocial context effect that rarely studied Patients with irritable bowel syndrome (IBS) exhibit hyperalgesia heightened affective/cognitive region activation stimuli. Psychological factors alter pattern, these changes are more pronounced Expectation...
Irritable bowel syndrome (IBS) and migraine are distinct clinical disorders. Apart from the characteristics of chronic recurrent pain in nature, these pain-related disorders apparently share many similarities. For example, IBS is female predominant with community prevalence about 5-10%, whereas that 1-3% also showing predominance. They often associated somatic psychiatric comorbidities terms fibromyaglia, fatigue syndrome, interstitial cystitis, insomnia depression etc., even subjects may...
The association between selective serotonin receptor inhibitors (SSRIs) and risk of upper gastrointestinal bleeding remains controversial. Previous studies have generally evaluated the issue for approximately 3 months, even though SSRI-mediated inhibition platelet concentrations occurs within 7-14 days. authors explored after short-term SSRI exposure by a case-crossover design.The records psychiatric inpatients with were retrieved from Taiwan National Health Insurance Database (1998-2009)....
Abstract Visceral hypersensitivity in gastric fundus is a possible pathogenesis for functional dyspepsia. The cortical representation of still unclear. Growing evidence shows that the insula, but not primary or secondary somatosensory region (SI SII), may be target visceral pain. Animal studies have also demonstrated amygdala plays an important role processing We used fMRI to study central projection stomach pain from balloon distension. tested hypothesis there will neither S1 nor S2...
Abstract Objective Until now, the epidemiology of functional dyspepsia (FD) and its social impact on Asians have been rarely studied. The aims this study were to determine prevalence, impact, health-seeking behaviors FD in an apparently healthy Chinese population Taiwan. Material methods Based questionnaire provided by Rome II working team, a survey was administered Taiwanese receiving paid physical check-up (n=2865). Esophagoduodenoscopy performed each subject exclude organic dyspepsia....
Visceral pain/discomfort is the cardinal complaints and treatment targets for functional gastrointestinal disorders (FGID). However, effective such pain limited often associated with high placebo effects. The mechanisms of effects in visceral are unclear. We used neuroimaging to study central representations effect its anticipation during esophageal healthy adults. Fourteen subjects were enrolled. Pain extent, psychophysical inventories [Pain Catastrophizing Scale (PAS), visual analogue...
The development-processes by regional socio-cultural adaptation of an Enhanced Asian Rome III questionnaire (EAR3Q), a cultural the diagnostic (R3DQ), and its translation-validation in languages are presented. As English is not first language for most Asians, EAR3Q essential. Hence, we aimed to culturally adapt R3DQ develop linguistically validate it show that able allocate diagnosis according criteria.After was developed experts consensus, translated into Chinese, Hindi-Telugu, Indonesian,...
Abstract Background and Aims Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disorder with increasing global prevalence. The risk of IBD in patients schizophrenia remains unclear. We aim to investigate the new‐onset compared matched controls. Methods conducted retrospective, population‐based cohort study utilising patient data from Taiwan National Health Insurance Research Database collected between January 1, 2001, December 31, 2011. Patients diagnosed by...
Depression is associated with gut dysbiosis that disrupts a gut-brain bidirectional axis. Gray matter volume changes in cortical and subcortical structures, including prefrontal regions the hippocampus, have also been noted depressive disorders. However, link between microbiota brain structures depressed patients remains elusive. Neuropsychiatric measures, stool samples, structural images were collected from 36 late-life depression (LLD) 17 healthy controls. 16S ribosomal RNA (rRNA) gene...
Background: Achalasia is a rare disease of gastrointestinal motility characterized by impaired esophageal peristalsis and reduced sphincter relaxation. However, data on its epidemiology outcomes in Taiwan are limited. This study aimed to assess the incidence, characteristics, clinical management achalasia Taiwan. Methods: Patients who were newly diagnosed with between 2001 2013 recruited from National Health Insurance Research Database. The obtained age, sex, urbanization, socioeconomic...
Summary Background : Irritable bowel syndrome is a common condition seen in Western countries. In Asia, however, it less known and even studied. Aim To determine the prevalence social impact of irritable as well health‐seeking behaviour patients Taiwan Methods Using modified Rome II questionnaire, survey was carried out population receiving physical check‐up ( n = 2865). Results The 22.1% 17.5% (κ 0.73) according to I criteria, respectively. No gender difference found between subjects with...
To assess the prevalence and risk factors of gallstone disease (GSD) in Taiwan.Descriptive cross-sectional.A prospective ultrasonographic study GSD was conducted 3647 Chinese subjects who received a paid hospital physical check-up. Their demographic characteristics biochemical parameters were recorded compared. Ultrasonographic diagnosis revealed 2946 (M/F: 1838/1108) with normal gallbladder, 286 196/90) gallbladder stones, 100 56/44) previous cholecystectomy for gallstones, 243 174/69)...