A5018158728- Metastasis and carcinoma case studies
- Thyroid Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Nutrition, Genetics, and Disease
- Immune cells in cancer
- Gastrointestinal Tumor Research and Treatment
- Photosynthetic Processes and Mechanisms
- Sports Performance and Training
- Eosinophilic Esophagitis
- Lung Cancer Research Studies
- Plant Gene Expression Analysis
- IL-33, ST2, and ILC Pathways
- Lung Cancer Treatments and Mutations
- Bioactive natural compounds
- Liver Disease Diagnosis and Treatment
- Glutathione Transferases and Polymorphisms
- Ferroptosis and cancer prognosis
- Grey System Theory Applications
- Traditional Chinese Medicine Analysis
- Physical Education and Pedagogy
- Inflammasome and immune disorders
- Eicosanoids and Hypertension Pharmacology
- Bioactive Compounds and Antitumor Agents
- Microbial Natural Products and Biosynthesis
Chinese Academy of Sciences
2000-2024
Jiangsu Cancer Hospital
2021-2024
Nanjing Medical University
2021-2024
University of Macau
2024
Zhejiang Cancer Hospital
2024
Zhejiang Chinese Medical University
2024
First Hospital of China Medical University
2023
Zhejiang University
2021-2023
China Medical University
2023
Jingchu University of Technology
2023
Thyroid cancer (TC) is the most common endocrine malignancy with increasing incidence in recent years. Fine-needle aspiration biopsy (FNAB), as a gold standard for initial evaluation of thyroid nodules, fails to cover all cytopathologic conditions resulting overdiagnosis. There an urgent need better classification from benign nodules (BTNs). Here, data independent acquisition (DIA)-based proteomics and untargeted metabolomics plasma samples 10 patients TC 15 BTNs were performed. Key proteins...
Abstract Alcoholic liver disease ( ALD ) is a complication that burden on global health and economy. Interleukin‐33 IL ‐33) newly identified member of the ‐1 cytokine family released as an “alarmin” during inflammation. Soluble suppression tumourigenicity 2 sST 2), ‐33 decoy receptor, has been reported new biomarker for severity systemic highly inflammatory diseases. Here, we found levels plasma 2, increased with from mild to severe . Importantly, in patients not only correlated scores...
Abstract Alcoholic liver disease ( ALD ) is a progressive that can cause series of complications, including cirrhosis, failure and hepatocellular carcinoma. Granulocytic myeloid‐derived suppressor cell gMDSC populations have been observed to expand in various diseases inhibit innate adaptive immunity patients with disease. However, the characteristics s not studied. We studied 24 healthy controls HC s) 107 found an accumulation peripheral blood alcoholic cirrhosis ALC ). Furthermore, poor...
To investigate the clinical and pathological features of multiple primary malignant neoplasms (MPMNs) cases.The data 24 105 tumour patients admitted to Jiangsu Cancer Hospital in 2018 were retrospectively reviewed, 270 with MPMNs selected as research subjects. Among them, 101 cases synchronous carcinoma (SC) 92 metachronous (MC) divided into groups for statistical analysis. Univariate multivariate cox regression analyses conducted using SPSS 22.0 software.Among cases, there was a...
Moracins, a kind of 2-phenyl-benzofuran compound from Moraceae, serve as phytoalexins with antimicrobial, anti-inflammatory, antitumor, and antidiabetes activities respond to biotic abiotic stresses, while their biosynthetic pathway regulatory mechanism remain unclear. Here, we report de novo transcriptome sequencing for different tissues seedlings, well leaves under in M. alba L. A total 88 282 unigenes were assembled an average length 937 bp, 82.2% them annotated. On the basis differential...
Stomach adenocarcinoma (STAD) is the most common histological type of stomach cancer, which causes a considerable number deaths worldwide. This study aimed to identify its potential biomarkers with notion revealing underlying molecular mechanisms.Gene expression profile microarray data were downloaded from Gene Expression Omnibus (GEO) database. The "limma" R package was used screen differentially expressed genes (DEGs) between STAD and matched normal tissues. Database for Annotation,...
With the help of DrugBank, TTD and SuperPred, action targets lobotropin were screened, gastric cancer identified by DisGeNET, MalaCards DigSee, two taken to intersect, there 13 identical targets, namely: HSP90AA1, NFKB1, MMP1, MMP2, OGG1, ABCC1 , CXCR4, MTOR, ESR1, TLR4, AR, NFE2L2 ITGB1, above genes differentially expressed in analysis TCGA database. Drug-target-disease-pathway mapping, target interaction (PPI) network construction KEGG GO common screened five significant as MTOR...
e16044 Background: The prognosis of metastatic/locally advanced EC has significantly improved with the development immune checkpoint inhibitors. Serplulimab been approved in treatment various solid tumors (e.g. esophageal squamous cell carcinoma [ESCC], small lung cancer). Considering lack real-world evidence, this study aimed to explore effectiveness and safety serplulimab as first-line therapy patients EC. Methods: Thismulticenterretrospective included who received serplulimab-containing...
The prognosis difference based on the depth of tumor muscularis propria invasion in gastric cancer (GC) was still debated, and therapy strategy for stage IB GC patient required further investigation.A total 380 patients with pT2 after radical surgery were retrospectively analyzed, including 185 superficial (sMP) group 195 deep (dMP) group.The overall survival (OS) significantly better sMP than dMP (P = 0.007). In multivariate analysis, invasion, pN stage, age, primary location, positive...
Abstract Purpose: The purpose of this study was to evaluate the value circulating cell-free DNA (cfDNA) as a biomarker for predicting efficacy first-line chemotherapy in patients with metastatic colorectal cancer (mCRC). Methods: A total 118 mCRC who received Jiangsu Cancer Hospital from July 2018 April 2020 were enrolled. CfDNA quantitatively detected plasma collected before and during chemotherapy. Correlations between cfDNA baseline levels clinicopathological characteristics, kinetics...
According to the excellent 110-meter hurdles athletes registered in ITFA (International Track and Field Association) from around world, a variety of Grey Prediction methods are employed predict each athlete's individual development as well pattern world's coming 2 years. Additionally, Liu Xiang's best competitive standard which he may reach 2012 major environments be faced discussed. This paper provides detailed suggestions training preparation London Olympics.
Purpose The purpose of this paper is to research comprehensively into the development pattern world's 110‐meter hurdles coming two years. It aims provide a detailed reference preparation 2012 London Olympics. Design/methodology/approach uses GM (2, 1) model, (1, residual fixing and method recursive compensation by grey numbers identical dimensions. Findings In 2012, strongest athletes are predicted be: USA athlete Oliver, Ash Cuba Robles. Liu Xiang has possibility winning medal in Practical...