A5068649453- Gastrointestinal motility and disorders
- Sexual Differentiation and Disorders
- Child Nutrition and Feeding Issues
- Infant Health and Development
- Reproductive Health and Technologies
- Gut microbiota and health
- Pediatric Pain Management Techniques
- Clostridium difficile and Clostridium perfringens research
- LGBTQ Health, Identity, and Policy
- Urological Disorders and Treatments
- Diet and metabolism studies
- Gastroesophageal reflux and treatments
- Ethics and Legal Issues in Pediatric Healthcare
- Intestinal Malrotation and Obstruction Disorders
- Hormonal and reproductive studies
- Cleft Lip and Palate Research
- Congenital gastrointestinal and neural anomalies
- Urinary Tract Infections Management
- Adolescent and Pediatric Healthcare
- COVID-19 and healthcare impacts
- Infant Development and Preterm Care
- Pelvic floor disorders treatments
- Diversity and Career in Medicine
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Probiotics and Fermented Foods
Phoenix Children's Hospital
2016-2024
University of Arizona
2022-2024
Research Network (United States)
2022
Brigham and Women's Faulkner Hospital
2022
University of Phoenix
2022
Baylor College of Medicine
2009-2021
Texas Children's Hospital
2009-2021
Children's Nutrition Research Center at Baylor College of Medicine
2010-2021
United States Department of Agriculture
2009-2021
Arkansas Children's Nutrition Center
2016-2021
The gut microbiome influences myriad host functions, including nutrient acquisition, immune modulation, brain development, and behavior. Although human microbiota are recognized to change as we age, information regarding the structure function of during childhood is limited. Using 16S rRNA gene shotgun metagenomic sequencing, characterized structure, function, variation healthy pediatric in a cohort school-aged, pre-adolescent children (ages 7–12 years). We compared with that adults...
Accurate diagnosis and stratification of children with irritable bowel syndrome (IBS) remain challenging. Given the central role recurrent abdominal pain in IBS, we evaluated relationships pediatric IBS intestinal microbes fecal metabolites using a comprehensive clinical characterization multiomics strategy. Using rigorous phenotyping, identified preadolescent (aged 7 to 12 years) Rome III (n = 23) healthy controls 22) characterized their microbial communities whole-genome shotgun...
This survey study aims to determine the prevalence of pregnancy complications and infertility in female physicians comparison general population. Risk factors, workplace environment, education are also examined.Physicians undertake long training have stressful work environments during optimal childbearing years. While growing literature indicates increased rates surgeons, all specialties is unknown.An anonymous, voluntary was distributed via private physician social media groups. It queried...
Anxiety and depression are implicated as contributors to abdominal pain in pediatric irritable bowel syndrome (IBS) but is unclear if this associated with other psychological factors. The study objective was test the impact of anxiety or on IBS symptom severity mediated by somatization and/or catastrophizing.We utilized baseline data from local clinical studies. Through mediation analysis, we assessed whether catastrophizing (either independently combined) separate relationships severity.We...
Traditional imaging modalities used to assess velopharyngeal insufficiency (VPI) do not allow for direct visualization of underlying (VP) structures and musculature which could impact surgical planning. This limitation can be overcome via structural magnetic resonance (MRI), the only current tool that provides salient VP structures. MRI has been extensively in research; however, it had limited clinical use. Factors restrict use include access optimized protocols uncertainty regarding how...
OBJECTIVE. The objectives of this study were to (1) compare the cost medical evaluation for children with functional abdominal pain or irritable bowel syndrome brought a pediatric gastroenterologist versus who remained in care their pediatrician, (2) symptom characteristics primary tertiary care, and (3) examine if predicted evaluation. METHODS. Eighty-nine aged 7 10 years seen by (n = 46) only pediatrician 43) completed daily stool diaries 2 weeks. Mothers provided retrospective reports...
Paediatric classification of irritable bowel syndrome (IBS) is complicated by the potential discrepancy between parent and child report interpretation pain-stool relations in Rome III system.To compare IBS diary respondents.Children (ages 7-10 years, n = 90) with recurrent abdominal pain their parents completed symptom questionnaires 2-week stool diaries. Diaries were coded two algorithms, one defining changes individually normatively. Proportions dichotomous classifications (IBS vs. not...
Introduction Advocacy and human rights organizations have called for a moratorium on elective surgical procedures until the patient is able to fully participate in decision-making process. Due controversial nature surrounding surgery differences of sex development (DSD) care, we aimed assess factors that teens adults with DSD, parents, healthcare providers other allied professionals consider pertinent complex decisions DSD. Methods Stakeholders (n=110) DSD care participated semi-structured...
Abstract Background In functional gastrointestinal disorders, patient recall of symptoms drives diagnostic decisions and evaluation treatment response, research conclusions about potential treatments. pediatrics, parent report also impacts assessment care. Hence, identifying methods for accurately capturing irritable bowel syndrome ( IBS ) is important. This study evaluated correspondence between retrospective questionnaire (parent child report) prospective diary data children adolescents...
OBJECTIVES To identify the most important attributes related to process of achieving, and outcomes associated with, successful care for differences sex development (DSD). METHODS We developed a best–worst scaling survey administered 520 DSD stakeholders, including individuals or family members those with DSD, health specialists, patient support advocacy representatives. Fourteen process-related 16 outcome-related were identified through qualitative research. estimated relative importance...
Background: Little is known regarding the clinical impact of treatment and duration probiotic VSL#3 on gut microbiome function in irritable bowel syndrome (IBS). As part a safety trial, we assessed effect abdominal pain, stooling, permeability, composition function. Methods: Adults with IBS were randomized into an open label trial to receive for 4 or 8 weeks. Adverse events, stooling patterns recorded daily. Gut fecal bile acid levels, profiled at baseline after treatment. Results: Fifteen...
Utilization of a psychosocial screener to identify families affected by disorder/difference sex development (DSD) and at risk for adjustment challenges may facilitate efficient use team resources optimize care. The Psychosocial Assessment Tool (PAT) has been used in other pediatric conditions. current study explored the reliability validity PAT (modified within DSD population; PAT-DSD).Participants were 197 enrolled DSD-Translational Research Network (DSD-TRN) who completed PAT-DSD during...