- Temporomandibular Joint Disorders
- Laser Applications in Dentistry and Medicine
- Particle Detector Development and Performance
- Wastewater Treatment and Nitrogen Removal
- Microbial bioremediation and biosurfactants
- CCD and CMOS Imaging Sensors
- Radiation Detection and Scintillator Technologies
- Myofascial pain diagnosis and treatment
- Particle Accelerators and Free-Electron Lasers
- Analog and Mixed-Signal Circuit Design
- Adsorption and biosorption for pollutant removal
- Nerve injury and regeneration
- Extracellular vesicles in disease
- Superconducting Materials and Applications
- Infrared Thermography in Medicine
- Aquatic Ecosystems and Phytoplankton Dynamics
- Nuclear Physics and Applications
- Oil Spill Detection and Mitigation
- Constructed Wetlands for Wastewater Treatment
- Osteoarthritis Treatment and Mechanisms
- Radiation Effects in Electronics
- Ginseng Biological Effects and Applications
- Berberine and alkaloids research
- Medical Research and Treatments
- Vitamin C and Antioxidants Research
Chinese Academy of Sciences
2016-2025
Institute of Modern Physics
2002-2025
Ningxia Medical University
2025
Fudan University
2024
Lanzhou University of Technology
2024
University of Chinese Academy of Sciences
2021-2024
Ji Hua Laboratory
2024
Air Force Medical University
2019-2023
University of Science and Technology of China
2020-2023
Hainan Medical University
2019-2022
Abstract Background The development of new treatment strategies to improve peripheral nerve repair after injury, especially those that accelerate axonal regeneration, is very important. aim this study elucidate the molecular mechanisms how bone marrow stromal cell (BMSC)-derived exosomes (EXOs) participate in regeneration and whether regenerative effect EXOs correlated with dose. Method BMSCs were transfected or without an siRNA targeting Ago2 (SiAgo2). extracted from administered dorsal...
Abstract “A Craftsman Must Sharpen His Tools to Do Job,” said Confucius. Nuclear detection and readout techniques are the foundation of particle physics, nuclear astrophysics reveal nature universe. Also, they being increasingly used in other disciplines like power generation, life sciences, environmental medical etc. The article reviews short history, recent development, trend techniques, covering Semiconductor Detector, Gaseous Scintillation Cherenkov Transition Radiation Readout...
On-site diagnostic tests that accurately identify disease biomarkers lay the foundation for self-healthcare applications. However, these routinely rely on single-mode signals and suffer from insufficient accuracy, especially multiplexed point-of-care (POCTs) within a few minutes. Here, this work develops dual-mode multiclassification platform integrates an electrochemiluminescence sensor field-effect transistor in microfluidic chip. The channel guides testing samples to flow across...
Platinum-based cytotoxic chemotherapy is considered the standard treatment for advanced gastric cancer (GC). However, cisplatin chemoresistance often occurs with mechanisms being not well clarified, which results in recurrence and poor survival. Ginsenoside Rg3, isolated from Chinese Herb Panax Ginseng, recognized as an anti-cancer agent. Herein, we aimed to reveal whether Rg3 alleviates resistance sensitizes GC cells cisplatin-induced apoptosis, draw out underlying molecular mechanism...
To evaluate the therapeutic effect of a modified Devine procedure with subcutaneous sliding fixation method for treatment congenital concealed penis, we retrospectively selected 45 patients penises who were admitted to General Hospital Ningxia Medical University (Yinchuan, China) between September 2020 and November 2023. In all cases, penis was observed be short, retracting skin at base revealed normal penile body, which immediately returned its original position upon release. All underwent...
We investigated the occurrence of mesenchymal stem cell (MSC)-derived exosome uptake and retrograde transport at peripheral nerve endings using bone marrow MSCs (bMSCs) transduced with recombinant CD63-green fluorescent protein (GFP) lentiviral plasmid. GFP was used to track release bMSC-derived exosomes terminals, dorsal root ganglion (DRG), spinal cord. In vitro culture injection a CD63-GFP suspension into right gastrocnemius muscle an in vivo rat model were also performed. Fluorescence...
Background: In this study, we analyzed whether the neuroprotection of Circ 0000962 promoted neural inflammation in spinal cord injury (SCI) and its possible mechanism.
Particle tracking systems, which function either as particle detectors or beam monitors, are the critical elements for high-intensity heavy-ion accelerator facility (HIAF) complex. The novel Topmetal-M pixel sensor, combines features of both monolithic active sensor (MAPS) and Topmetal can be used a detector nondestructive monitor. got its name some part pixel’s top metal layer is exposed to sense drifting charge. In this article, prototype system, named Hi’Beam-S, has been...
As the leading research platform of heavy-ion science in China, physics and applications at Heavy Ion Research Facility Lanzhou (HIRFL) High-Intensity Accelerator (HIAF) drive development new detector technology. A monolithic active pixel sensor (MAPS) has been designed a 130-nm CMOS process for HIRLF HIAF. This MAPS can measure energy deposition position particle hit. critical component this MAPS, regional 12-bit 40-Msps pipeline ADC to convert analog signals from pixels into digital data....
The berberine bridge enzyme (BBE)-like flavoproteins have attracted continuous attention for their capability to catalyze various oxidative reactions. Here we demonstrate that MitR, a secreted BBE-like enzyme, functions as special drug-binding efflux protein evolved from quinone reductase. Moreover, this provides self-resistance its hosts toward the DNA-alkylating agent mitomycin C with distinctive strategy, featured by independently performing drug binding and efflux.
Poplars produce quantities of leaves during their growth, which are usually burned or deserted directly. In this study, the deciduous were reclaimed and made into organic granules. During granulation, adsorption capacity was not obviously depressed compared with leaf powder, but granules more convenient to be separated from solution after saturation. Being under relatively low temperature 378 K, material maintained natural structure ingredients poplar supplied nanolevel structures in cell...
The frequent occurrence of cyanobacterial blooms in eutrophic lakes can lead to a high amount biomass aquatic systems, and following cell death, this autochthonous organic matter will eventually decompose. In study, the effect temperature sediment on chemical composition residue was investigated by microcosm experiment. results showed that lowest bloom (CBB) removal efficiency recorded at 32°C regardless presence or absence sediment. Based total carbon, CBB efficiencies were higher than 90%...