A5100353234- Traditional Chinese Medicine Analysis
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Medical Research and Treatments
- Traditional Chinese Medicine Studies
- RNA modifications and cancer
- MicroRNA in disease regulation
- Pharmacological Effects of Natural Compounds
- Cancer-related Molecular Pathways
- Natural product bioactivities and synthesis
- Hepatocellular Carcinoma Treatment and Prognosis
- Berberine and alkaloids research
- Cancer-related molecular mechanisms research
- Phytochemistry and Biological Activities
- Circular RNAs in diseases
- Healthcare and Venom Research
- Acupuncture Treatment Research Studies
- Educational Reforms and Innovations
- Metabolomics and Mass Spectrometry Studies
- Regional Development and Environment
- Chromatography in Natural Products
- Business and Economic Development
- Cancer Mechanisms and Therapy
- Cholesterol and Lipid Metabolism
- Cancer Cells and Metastasis
Foshan Hospital of TCM
2024
Dalian Polytechnic University
2024
Heilongjiang University of Chinese Medicine
2013-2023
Guangzhou Medical University
2020-2023
Third Affiliated Hospital of Guangzhou Medical University
2023
Beijing Biocytogen (China)
2023
First Affiliated Hospital of Kunming Medical University
2023
Kunming Medical University
2023
First Hospital of Jilin University
2022
Tulane University
2022
Increasing evidence has suggested that microRNAs (miRNAs) play an important role in the initiation and progression of hepatocellular carcinoma (HCC). Here, we identified a novel tumor suppressive miRNA, miR-377, investigated its HCC. The expression miR-377 HCC tissues cell lines was detected by real-time reverse-transcription PCR. effects on proliferation invasion were also investigated. Western blot luciferase reporter assay used to identify direct functional target miR-377. markedly...
Pyruvate carboxylase (PC) is an important anaplerotic enzyme in the tricarboxylic acid cycle (TCA) cancer cells. Although PC overexpression has been observed thyroid (TC), mechanisms involved carcinogenic effects of are still unclear.Bioinformatics analysis and clinical specimens were used to analyze relationship expression with clinicopathological variables TC. Fatty synthesis was monitored by LC/MS, Nile red staining, triglyceride analysis. Mitochondrial oxygen consumption evaluated...
Traditional Chinese Medicine (TCM) has been used in clinical practice for several thousand years, with an indispensable role prevention and treatment of disease using multiple ingredients.
A large panel of molecular biomarkers have been identified to predict the prognosis hepatocellular carcinoma (HCC), yet with limited clinical application due difficult extrapolation. We here generated a genetic risk score system comprised 12 HCC-specific genes better HCC patients. Four genomics profiling datasets (GSE5851, GSE28691, GSE15765 and GSE14323) were searched seek by comparisons between cancer samples normal liver tissues different subtypes hepatic neoplasms. Univariate survival...
ZDHHC-protein acyltransferases (ZDHHCs) are a family of 23 signature Asp-His-His-Cys (DHHC) domain-containing enzymes that mediate palmitoylation by covalent attachment the 16-carbon fatty acid palmitate to thiol groups specific cysteine residues in substrate proteins. Emerging evidence has shown abnormal expression ZDHHCs variety disease states, including cancer. Kidney renal clear cell carcinoma (KIRC) is eighth most common type cancer, which accounts for majority malignant kidney tumors....
MicroRNA (miR)-29a has been associated with carcinogenesis in humans; however, its functional significance esophageal squamous cell carcinoma (ESCC) is yet to be determined. In the present study, expression of miR-29a was markedly downregulated ESCC tissue and TE-1 line, compared normal cells. Furthermore, study identified that forced cells significantly reduced proliferation migration. overexpression did not affect Notch1, it increase gene levels hairy enhancer split 1 (Hes1), which key...
Journal Article Outcome Literature Review of Integrative Body–Mind–Spirit Practices for Mental Health Conditions Get access Mo Yee Lee, Lee Address correspondence to Ohio State University, 440 Stillman Hall, 1947 College Road, Columbus, OH 43210; e-mail: lee.355@osu.edu. Search other works by this author on: Oxford Academic Google Scholar Xiafei Wang, Wang Chang Liu, Liu Salome Raheim, Raheim Susan Tebb Social Work Research, Volume 42, Issue 3, September 2018, Pages 251–266,...
Four new glycosides, namely 3β-norpinan-2-one 3-O-β-d-apiofuranosyl-(1→6)-β-d-glucopyranoside (1), (6Z)-3-hydroxymethyl-7-methylocta-1,6-dien-3-ol 8-O-β-d-glucopyranoside (2), (6E)-3-hydroxymethyl-7-methylocta-1,6-dien-3-ol 8-O-β-d-gluco-pyranoside (3), and 7-[(β-d-apiofuranosyl-(1→6)-β-d-glucopyranosyl)oxymethy]-8,8-dimethyl-4,8-dihydrobenzo[1,4]thiazine-3,5-dione (4), were isolated from the fruits of Xanthium sibiricum Patr together with three known compounds, xanthiside (5), adenosine...
Traditional Chinese Medicine Constitution (TCMC) theory states that individuals with a biased TCMC are more likely to suffer from specific diseases. However, little is known regarding the influence of on susceptibility hypertension. The aim this study examine possible relationship between and Retrospective evaluation observation were performed using STROBE guidelines checklist. A large community-based cross-sectional was conducted 2009 2013 in Changsha, China. assessed questionnaire included...
The Chinese formula Pien Tze Huang (PZH) has been used to treat hepatocellular carcinoma (HCC) and showed positive clinical effects. However, the antitumor mechanism of PZH in HCC remains unclear. In this study, xenograft Balb/c mice were treated with PZH; then, proteomics detection Ingenuity Pathway Analysis (IPA) analyze differentiated phosphorylated proteins tumor tissues. results indicated that could inhibit weight by 50.76%. Eighty-four upregulated 11 downregulated identified...
Ulcerative colitis (UC) is a chronic nonspecific inflammatory disease of the colon and rectum with unknown etiology, its symptoms include bloody diarrhea, abdominal pain, hematochezia. Traditional Chinese medicine compound has good therapeutic, multi-target effect on UC. Ganjiang decoction (GD), which traditional classic prescription in China, contains Zingiberis Rhizoma, Angelicae Sinensis Radix, Coptidis Phellodendri Chinensis Cortex, Sanguisorbae Granati Pericarpium, Asini Corii Colla...