- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Takotsubo Cardiomyopathy and Associated Phenomena
- Botulinum Toxin and Related Neurological Disorders
- Venous Thromboembolism Diagnosis and Management
- Eicosanoids and Hypertension Pharmacology
- Cardiovascular Health and Disease Prevention
- COVID-19 Clinical Research Studies
- Blood Pressure and Hypertension Studies
- Cerebrovascular and Carotid Artery Diseases
- Vitamin K Research Studies
- Fatty Acid Research and Health
- Cardiac Structural Anomalies and Repair
- Literary and Cultural Studies
- Ion channel regulation and function
- Hormonal Regulation and Hypertension
- Congenital Heart Disease Studies
Hospital Universitario de Torrejón
2021-2024
Hospital Universitario Quirónsalud Madrid
2019-2023
Universidad Francisco de Vitoria
2021-2023
Hospital Ruber Internacional
2021
Universidad Europea
2019-2021
Hospital Universitario Fundación Jiménez Díaz
2021
Universidad Autónoma de Madrid
2021
University of Michigan
2017-2021
Hospital Universitario La Paz
2012-2019
Associazione Nazionale Medici Cardiologi Ospedalieri
2018
Post-COVID-19 patients may incur myocardial involvement secondary to systemic inflammation. Our aim was detect possible oedema/diffuse fibrosis using cardiac magnetic resonance imaging (CMR) mapping and study deformation of the left ventricle (LV) feature tracking (FT).Prospective analysis consecutively recruited post-COVID-19 undergoing CMR. T1 T2 sequences were acquired FT performed 2D steady-state free precession cine sequences. Statistical significance set p < 0.05.Included 57 20 healthy...
Aims and Objectives New electrophysiology tools like intracardiac echocardiography (ICE) might help to minimize early detect complications during cardiac ablation procedures. The aim of the study was assess utility vascular safety ICE catheter complex arrhythmias in a medium‐volume training center. Methods Prospective, observational consisted consecutive patients who underwent catheter‐based arrhythmias. All procedures were performed using three‐dimensional electro‐anatomical mapping routine...
The acetylcholine-activated inward rectifier potassium current (IKACh) is constitutively active in persistent atrial fibrillation (AF). We tested the hypothesis that blocking of IKACh with small molecule chloroquine terminates AF. used a sheep model tachypacing-induced, AF, molecular modeling, electrophysiology, and structural biology approaches. 50% inhibition/inhibitory concentration block chloroquine, measured by patch clamp, was 1 µM. In optical mapping hearts µM restored sinus rhythm....
Abstract Background The differential diagnosis of regular wide QRS complex tachycardia (RWQRST) remains the subject numerous publications, all which aim at during acute phase. Although an accurate is necessary to make long‐term decisions, it often leads invasive testing. Methods Criteria with high positive predictive values (PPVs) for can be obtained by analyzing electrocardiogram (ECG) data RWQRST and comparing them these baseline. By assigning points criteria, a scoring algorithm...
<h3>Objective</h3> A safety threshold for baseline rhythm R-wave amplitudes during follow-up of implantable cardioverter defibrillators (ICD) has not been established. We aimed to analyse the amplitude distribution and undersensing rate spontaneous episodes ventricular fibrillation (VF), define a R-waves. <h3>Methods</h3> Data were obtained from an observational multicentre registry conducted at 48 centres in Spain. Baseline VF events prospectively registered by remote monitoring. Signal...
Atrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice with growing prevalence developed countries. Several medical and interventional therapies, such as atrial specific drugs pulmonary vein isolation, have demonstrated prevention of recurrences. However, their suboptimal long-term success significant rate secondary effects led to intensive research last decade focused on novel alternative supplemental therapies. One candidate polyunsaturated fatty...
Background Activation during onset of atrial fibrillation is poorly understood. We aimed at developing a panoramic optical mapping system for the atria and test hypothesis that sequential rotors underlie acceleration onset. Methods Results Five sheep hearts were Langendorff perfused in presence 0.25 µmol/L carbachol. Novel recorded activations simultaneously from entire left right endocardial surfaces. Twenty sustained (>40 s) episodes induced by train premature stimuli protocol. Movies...
Ventricular overdrive pacing (VOP) produces reset during the transition zone (TZ) of QRS fusion in orthodromic reentrant tachycardia (ORT) and after TZ atrioventricular nodal (AVNRT), this represents a simple diagnostic maneuver to differentiate two mechanisms.The purpose study was determine whether number beats with predicts accessory pathway (AP) location ORT.We retrospectively reviewed 57 patients ORT (21 left-sided AP, 20 septal 16 right-sided AP) AVNRT (19 typical one atypical AVNRT)...
Abstract Background/Introduction The deleterious effects of long-term RV apical pacing have been well recognized. Permament His bundle (HB) has emerged as a promising technique for patients who need ventricular pacing. Purpose To describe the anatomy HB region and its variations successfully approaching in safer more efficient way to understand selective vs non-selective avoid permanent damage it. Methods In 57 structurally normal human heart specimens (48 males, 77±7 years) we examined by...
Métodos: Estudio multicéntrico retrospectivo realizado en 15 hospitales españoles.Cada centro incluyó consecutivamente a los pacientes sometidos implante de desfibrilador prevención primaria durante al menos 2010 y 2011.Resultados: De 1,174 pacientes, 34 (2.9%) presentaron un episodio tormenta arrítmica, principalmente secundaria taquicardia ventricular (82.4%).No se detectaron diferencias basales entre aquellos con sin tormenta, presentando similar puntuación scores mortalidad (SHOCKED,...
Background: Ventricular overdrive pacing (VOP) produces reset during the transition zone (TZ) of QRS fusion in orthodromic reentrant tachycardia (ORT) and after TZ atrioventricular nodal (AVNRT), this represents a simple diagnostic maneuver to differentiate 2 mechanisms. Objective: The purpose study was determine whether number beats with predicts accessory pathway (AP) location ORT. Methods: We retrospectively reviewed 57 patients ORT (21 left-sided AP, 20 septal 16 right-sided AP) AVNRT...