- Insect-Plant Interactions and Control
- Insect Resistance and Genetics
- Plant tissue culture and regeneration
- Soil Carbon and Nitrogen Dynamics
- Insect Pest Control Strategies
- Barrier Structure and Function Studies
- Plant Water Relations and Carbon Dynamics
- Inflammasome and immune disorders
- Hungarian Social, Economic and Educational Studies
- Plant Genetic and Mutation Studies
- Insect and Pesticide Research
- Plant responses to elevated CO2
- Neurological Disease Mechanisms and Treatments
- Brain Metastases and Treatment
- Cancer Cells and Metastasis
- Glioma Diagnosis and Treatment
- Soil erosion and sediment transport
- Horticultural and Viticultural Research
- Plant Physiology and Cultivation Studies
- Ecology and Vegetation Dynamics Studies
- Genetically Modified Organisms Research
- Remote Sensing in Agriculture
- Connexins and lens biology
- Agricultural pest management studies
- Flowering Plant Growth and Cultivation
Institute of Biophysics
2019-2024
University of Szeged
2018-2024
HUN-REN Szegedi Biológiai Kutatóközpont
2018-2024
Magyar Agrár- és Élettudományi Egyetem
2001-2024
Hungarian Research Network
2021-2023
Agroécologie
2023
National Research, Development and Innovation Office
2022
University of Pannonia
2022
Innova (Hungary)
2022
Hungarian Academy of Sciences
2008-2019
Abstract Breast cancer and melanoma are among the most frequent types leading to brain metastases. Despite unquestionable clinical significance, important aspects of development secondary tumours central nervous system largely uncharacterized, including extravasation metastatic cells through blood‐brain barrier. By using transmission electron microscopy, here we followed interactions endothelial during adhesion, intercalation/incorporation transendothelial migration steps. We observed that...
Peripheral nerve injuries are accompanied by inflammatory reactions, over-activation of which may hinder recovery. Among pro-inflammatory pathways, inflammasomes one the most potent, leading to release active IL-1β. Our aim was understand how participate in central reactions accompanying peripheral injury.After axotomy sciatic nerve, priming and activation NLRP3 inflammasome examined cells spinal cord. Regeneration evaluated after coaptation using functional index measurements retrograde...
Arbuscular mycorrhizal fungi (AMF) as symbiotic microorganisms mediate carbon allocation between plants and soil by acting a pathway of to organic matter atmosphere through respiration. In 2022 an experiment focusing on the  contribution respiration was set up in Central-Hungarian dry sandy grassland. this drought prone area events occur throughout the year limited water availability causes seasonal changes plant growth, uptake thus well.During study CO2 gas exchange monitored two...
Like sun-induced fluorescence (SIF), LED-induced (LEDIF) became frequently used to establish and analyze leaf- canopy-level stress responses. Different plant phenotypes (trees, understory shrubs, crops, vineyards, etc.) were subjected to, in most of the studies, blue LED illumination during night or darkened boxes for assessing either entire broad-band (650-850 nm) spectrum LEDIF one wavelength bands red (~ 690 far-red 740 peak emissions. It seems be however less common apply close...
Brain metastases are life-threatening complications of triple-negative breast cancer, melanoma, and a few other tumor types. Poor outcome cerebral secondary tumors largely depends on the microenvironment formed by cells neurovascular unit, among which pericytes least characterized. By using in vivo vitro techniques human samples, here we show that play crucial role development metastatic brain directly influencing key steps disease. had prompt chemoattractant effect cancer established direct...
Inflammasomes, primarily responsible for the activation of IL-1β, have emerged as critical regulators tumor microenvironment. By using in vivo and vitro brain metastasis models, well human samples to study role NLRP3 inflammasome triple-negative breast cancer (TNBC) metastases, we found components IL-1β be highly specifically expressed peritumoral astrocytes. Soluble factors from TNBC cells induced upregulation astrocytes, while astrocyte-derived mediators augmented proliferation metastatic...
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and the <i>I</i><sub>h</sub> current they generate contribute to pathophysiological mechanisms of absence seizures (ASs), but their precise role in neocortical thalamic neuronal populations, main components network underlying AS generation, remains controversial. In diverse genetic models, amplitude is smaller neurons either larger or unchanged thalamocortical (TC) compared with nonepileptic strains. A lower expression HCN...
Therapeutic resistance of cerebral secondary tumours largely depends on unique aspects linked to the neurovascular unit, especially endothelial cells and astrocytes. By using advanced microscopy techniques, here we explored novel mechanisms related unit during extravasation proliferation triple negative breast cancer in brain. Metastatic mammary carcinoma arrested elongated within one hour microvessels, but their number decreased by almost 80% first two days. Interestingly, malignant induced...
Abstract Cerebral pericytes are mural cells covering brain microvessels, organized as ensheathing, mesh and thin-strand pericytes. These latter two, together called capillary pericytes, have low levels of alpha smooth muscle actin (α-SMA), regulating basal vascular tone applying a slow influence on cerebral blood flow. Pericytes subject to alterations in ageing which may be even more pronounced age-related pathologies, including microinfarcts, usually affect large number vessels the brain....
Infestations of two stem borers, Eoreuma loftini (Dyar) and Diatraea saccharalis (F.) (Lepidoptera: Crambidae), were compared in noncrop grasses adjacent to rice (Oryza sativa L.) fields. Three farms the Texas Gulf Coast production area surveyed every 6-8 wk between 2007 2009 using quadrat sampling along transects. Although D. densities relatively low, E. average ranged from 0.3 5.7 immatures per m2 throughout 2-yr period. Early annual including ryegrass, Lolium spp., brome, Bromus infested...
The Mexican rice borer, Eoreuma loftini (Dyar), is an invasive pest of rice, Oryza sativa L., in the Gulf Coast region United States. This also damages sugarcane, Saccharum spp. hybrids; corn, Zea mays L.; and sorghum, Sorghum bicolor (L.) Moench, feeds on weedy noncrop grasses. Multiple aspects integrated management including use pheromone traps, manipulation planting dates, harvest cutting height, stubble management, host soil fertility plant resistance, insecticides, biological control...
By upregulation of cell adhesion molecules and secretion proinflammatory cytokines, cells the neurovascular unit, including pericytes endothelial cells, actively participate in neuroinflammatory reactions. As previously shown, both types can activate inflammasomes, cerebral (CECs) through canonical pathway, while only noncanonical pathway. Using complex vitro models, we demonstrate here that inflammasome pathway be induced CECs as well, leading to a further increase active interleukin-1β...
In a two-year field study, sugarcane was planted on 4 dates ranging from the first week of Aug to third Nov, reproducing phenologies associated with planting and harvesting operations in Louisiana. Sugarcane early offered an extended period plant availability for borer, Diatraea saccharalis (F.), infestations during fall. Periodic sampling throughout fall showed that plantings had higher (P < 0.05) D. saccharalis-caused deadheart densities than later sugarcane. Destructive conducted Oct...
Abstract A greenhouse study compared oviposition preference and larval development duration of a stem borer, E oreuma loftini ( D yar) L epidoptera: C rambidae), on rice, O ryza sativa . cv ocodrie P oaceae), four primary non‐crop hosts T exas G ulf oast rice agroecosystems. Rice two perennials, johnsongrass, S orghum halepense .) ers., vaseygrass, aspalum urvillei teud. (both were assessed at three phenological stages. Two spring annuals, brome, B romus spec., ryegrass, olium spec....
Abstract Aims The relative importance of species within an ecosystem shows spatio‐temporal variability related to both the terrain features and numerous rapidly changing factors. Accordingly, functional patterns may show some level persistence, or, due various disturbances, fluctuations. Communities with high richness were found maintain a higher degree stability than species‐poor or perturbed vegetations; however, diversity its be spatio‐temporally variable. Based on these considerations,...
The 42 kDa endochitinase gene of Trichoderma hamatum was expressed in tobacco, led by the constitutive 35S promoter Cauliflower Mosaic Virus and inducible Actin 7 Arabidopsis thaliana. Transgenic tobacco events containing had increased chitinase levels leaves enhanced tolerance to Botrytis cinerea, but their stems were still susceptible infection. When used, resulting transgenic exhibited pathogen even stem. presence transgene monitored PCR analysis sequence product confirmed integration...
According to the Nomenclature of Territorial Units for Statistics (NUTS2) level data from Eurostat and Regional Innovation Scoreboard (RIS), a strong geographical concentration in field RDI can be observed Hungary.Regional disparities are more significant than most European Union (EU) member countries have not changed long time.The development regional innovation capacity is fundamental aspect an economic policy point view; therefore, Hungarian considers higher education institutions that...
Abstract Aims Soil respiration (R s ) is a complex process including wide range of soil biota and pathways carbon cycling, all being under the control various drivers. The most important biotic driver photosynthetic activity vegetation providing supply mainly for autotrophic component R : roots their symbiotic partners. objective this study was to describe time-lagged relationship between gross primary production (GPP) mycorrhizal in order determine amount derived from GPP appearing as myc...