A5101704296- Medicinal Plants and Neuroprotection
- Computational Drug Discovery Methods
- Natural Antidiabetic Agents Studies
- Cholinesterase and Neurodegenerative Diseases
- Geochemistry and Elemental Analysis
- Essential Oils and Antimicrobial Activity
- Geochemistry and Geologic Mapping
- CRISPR and Genetic Engineering
- Phytochemicals and Medicinal Plants
- CAR-T cell therapy research
- Phytochemistry and Bioactivity Studies
- Moringa oleifera research and applications
- Pharmacological Effects of Natural Compounds
- Marine Sponges and Natural Products
- Protein Hydrolysis and Bioactive Peptides
- Antioxidant Activity and Oxidative Stress
- Phytochemicals and Antioxidant Activities
- Fungal Biology and Applications
- Biological Activity of Diterpenoids and Biflavonoids
- Bone and Dental Protein Studies
- Food Safety and Hygiene
- Morinda citrifolia extract uses
- Ethnobotanical and Medicinal Plants Studies
- Endometrial and Cervical Cancer Treatments
- Machine Learning in Bioinformatics
University of Dhaka
2024
University of Rajshahi
2021-2023
University of Debrecen
2021
Gopalganj Science and Technology University
2021
Hajee Mohammad Danesh Science and Technology University
2015
Abstract Objectives In this present study, antioxidant, anti-hemolytic, cytotoxic and anti-bacterial activities derived from methanol extracts of Bruguiera gymnorrhiza Heritiera littoralis were investigated in order to determine their medicinal activities. Materials methods Folin-Ciocalteu reagent method aluminum chloride used the mangroves’ total phenolics flavonoid content, respectively. Antioxidant capacity was assessed via following methods: 1,1-diphenyl-2-picryl hydroxyl (DPPH), 43 mM H...
Medicinal plants possess a surplus of novel and biologically active secondary metabolites that are responsible for counteracting diseases. Traditionally, Gomphandra tetrandra (Wall.) Sleumer is used to treat mental disorders. The present research was designed explore phytochemicals from the ethanol leaf extract identify potential pharmacophore(s) in treatment neurological chemical compounds experimental plant were identified through GC-MS analysis. In-vitro antioxidant activity assessed...
ABSTRACT Major, trace, and rare‐earth elements (REEs) were examined on modern sediments of a 70‐m long core collected from the southeast coast Bangladesh to understand chemical weathering, paleo‐redox sensitivity, sediment maturity, source rock composition, tectonic setting during deposition sediments. The samples contained high SiO 2 (62–91 wt.%) low Al O 3 (~5–17 that showed marked negative correlation ( r = −0.98) with linear trends, indicating quartz rather than aluminosilicates mainly...
Background: SYK gene regulates the expression of kinase (Spleen tyrosine kinase), an important non-receptor protein-tyrosine for immunological receptor-mediated signaling, which is also considered a tumor growth metastasis initiator. An onco-informatics analysis was adopted to evaluate and prognostic value in colorectal cancer (CRC), third most fatal type; late, it may be biomarker as another targeted site CRC. In addition, identify potential phytochemicals that inhibit overexpression...
Background: “Dimocarpus longan Lour” is a tropical and subtropical evergreen tree species mainly found in China, India, Thailand; this plant, naturally Bangladesh, even locally, used as “kaviraj” medication for treating different diseases, such gastrointestinal disorders, wounds, fever, snake bites, menstrual problem, chickenpox, bone fractures, neurological reproductive health. Different parts of especially juice pulp, pericarp, seeds, leaves, flowers, contain diverse group botanical...
Endophytic fungi can thrive without producing illness or injury to the host plant tissues, and they are also one of major natural sources bioactive compounds. The objective present study was assess anticancer potential fungal extracts obtained from Ceriops decandra in-silico-based identification constituents those extracts. were isolated identified by internal transcribed spacer (ITS-rDNA) sequence analysis. crude extract subjected column chromatography different fractions screened for...
Cumulative studies have provided controversial evidence for the prognostic values of bone morphogenetic protein 5 (BMP5) in different types cancers such as colon, breast, lung, bladder, and ovarian cancer. To address inconsistent correlation BMP5 expression with patient survival molecular function relation to cancer progression, we performed a systematic study determine whether could be used marker human cancers. were assessed using bioinformatics tools ONCOMINE, GENT, TCGA, GEPIA, UALCAN,...
Morinda angustifolia Roxb. is used to treat jaundice in the indigenous system of medicine Bangladesh. The objective present study was assess hepatoprotective potential and silico-based identification active constituents M. bark extract. In vivo activity evaluated CCl4-induced hepatotoxicity rats. secondary metabolite content extract identified by ultra-performance liquid chromatography coupled with a quadrupole orbitrap mass spectrometer (UHPLC-Q/Orbitrap/MS). Furthermore,...
Abstract Background Wedelia chinensis has been reported as a folk medicine for the treatment of different diseases including neurodegenerative disease. Although plant studied well diverse biological activities, effect this in neurological disorder is largely unknown. The present study was undertaken to evaluate cholinesterase inhibitory and antioxidant potential W. . Methods extract fractions were evaluated acetylcholinesterase butyrylcholinesterase activity by modified Ellman method....
Abstract Purpose Cellulase, due to its massive applicability, has been used in various industrial processes such as biofuels (bioethanol, triphasic biomethanation), agricultural and plant waste management, chiral separation, ligand binding studies. The finding of a novel cellulase-producing bacterium will benefit the industries, which rely on yeast produce cellulase fermentation technology, because bacteria can easily be manipulated fermented cost-effectively. Methods Cellulase...
Wedelia chinensis is a folk medicine used in many Asian countries to treat various ailments. Earlier investigations reported that the petroleum ether extract of plant has potential biological activity, but compounds responsible for activity are not yet completely known. Therefore, current work was designed isolate and characterize from study their bioactivities. Four including two diterepenes (-) kaur-16α-hydroxy-19-oic acid (1) kaur-16-en-19-oic (2), steroids β-sitosterol (3),...
Milk is highly vulnerable to microbial contamination and consequently easily perishable. The aim of the present study was analysis raw pasteurized milk. For this, a total 32 milk samples (12 from 20 milk) were collected 8 sources. Among them three (R1 R3) sources rest five (P1 P5) Each investigated during period May December, 2012. All subjected viable count (TVC), coliform (TCC), Total Staphylococcus (TSC) Grams staining determine loads microbes in counts (TVC) range 12 (R, R2 1.3 x106 7.4...
Abstract The hyacinth bean protein hydrolysates (HPHs) were derived from concentrate (HPC) by enzymatic hydrolysis following isoelectric method using pepsin enzyme. HPH displayed strong antioxidant activities than flour and HPC, where released amino acids the major contributors to enhanced activities. IC 50 values for ascorbic acid (AA) 0.052 0.020 mg/ml correspondingly. total phenolic content (TPC) of HPC 35.1 22.03 mg GAE/g, respectively. potential both was assessed adding those components...
Medicinal plants possess a surplus of novel and biologically active secondary metabolites that are responsible for counteracting diseases. Traditionally, Gomphandra tetrandra (Wall.) Sleumer is used to treat mental disorders. The present research was designed explore phytochemicals from the ethanol leaf extract identify potential pharmacophore(s) in treatment neurological chemical compounds experimental plant were identified through GC-MS analysis. Besides, in-vitro antioxidant activity...
The mechanisms involved in immune responses to cancer have been extensively studied for several decades and, considerable attention has paid harnessing the system's therapeutic potential. Cancer immunotherapy established itself as a promising new treatment option variety of types. Various strategies including vaccines, monoclonal antibodies (mAbs), adoptive T-cell-cancer therapy and test gained prominence through immunotherapy. However, it remains be accomplished full potential In spite...
Geochemical analyses of major oxides, trace, and rare-earth elements (REE) were examined on the ~70 m core sediments collected from southeast coast Bangladesh to determine sediment provenance, maturity, chemical weathering conditions. The samples contained high SiO2 (62-91 wt.%) low Al2O3 (~5-17 contents showed a marked negative correlation (r = -0.99) with strong linear trends, indicating that was mainly controlled by quartz content rather than aluminosilicates. Substantial depletion labile...
Abstract An investigation on medium to coarse-grained quartz grains (QG) recovered from a ~ 100-m drilled core section of the Sundarbans Forest site in southwestern Bangladesh was carried out infer source and depositional environment. Thirty-six microtextures were identified 200 QG using scanning electron microscopy (SEM). The surface features are categorized into mechanical (number n = 25), chemical ( 5), combined 6), which provide invaluable insights transport mechanism, provenance,...