- Phytochemistry Medicinal Plant Applications
- Psoriasis: Treatment and Pathogenesis
- Helicobacter pylori-related gastroenterology studies
- Colorectal and Anal Carcinomas
- Cardiac Arrhythmias and Treatments
- Mycobacterium research and diagnosis
- Inflammatory Myopathies and Dermatomyositis
- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Solid-state spectroscopy and crystallography
- Cancer Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Transgenic Plants and Applications
- Adenosine and Purinergic Signaling
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Gastrointestinal disorders and treatments
- Crystal Structures and Properties
- Soft tissue tumor case studies
- Autoimmune and Inflammatory Disorders Research
- Immune Cell Function and Interaction
- Eosinophilic Esophagitis
- Glass properties and applications
University of Cape Town
2024
Buckinghamshire Healthcare NHS Trust
2024
Newcastle University
2024
NIHR Newcastle Biomedical Research Centre
2024
Roivant Sciences (United States)
2020-2023
University of Wisconsin–Madison
2023
Royal Stoke University Hospital
2021
Whipps Cross University Hospital
1989
Abstract Background The World Health Organization–approved Xpert MTB/XDR test detects Mycobacterium tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, injectable drugs directly in specimens. This pragmatic, laboratory-based study assessed the diagnostic accuracy feasibility of a reflex testing approach, where was performed on residual specimens previously processed for MTB/RIF Ultra. Methods Routine respiratory specimens, Ultra, were stored sample reagent buffer at...
Long-term outcomes in rheumatoid arthritis (RA) depend on early and effective disease control. Methotrexate (MTX) remains the first-line modifying therapy, however there are no biomarkers with which to identify those most likely achieve remission. To address this unmet need we explored metabolic pathways involved MTX mechanism of action within circulating CD4+T cells a cohort treatment naive patients RA.
Abstract not available.
Abstract Tapinarof is a first-in-class, nonsteroidal, topical, aryl hydrocarbon receptor agonist approved by the Food and Drug Administration for treatment of plaque psoriasis in adults, under investigation atopic dermatitis (AD) adults children. cream 1% once daily (QD) demonstrated significant efficacy vs. vehicle was well tolerated adolescents with moderate to severe AD previously reported phase 2b trial. The pharmacokinetic (PK) profile tapinarof across trials characterized no-to-minimal...
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