- Global Maternal and Child Health
- Child Nutrition and Water Access
- Sepsis Diagnosis and Treatment
- Emergency and Acute Care Studies
- Neonatal and Maternal Infections
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Infant Development and Preterm Care
- Hemodynamic Monitoring and Therapy
- Mobile Health and mHealth Applications
- Neonatal Respiratory Health Research
- Global Health and Epidemiology
- HIV/AIDS Research and Interventions
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Reforms
- Global Health and Surgery
- Nosocomial Infections in ICU
- Ethics in Clinical Research
- Respiratory viral infections research
- Non-Invasive Vital Sign Monitoring
- Pharmaceutical Practices and Patient Outcomes
- Family and Patient Care in Intensive Care Units
- Energy and Environment Impacts
- Mosquito-borne diseases and control
- Poisoning and overdose treatments
University of British Columbia
2016-2025
British Columbia Children's Hospital
2017-2025
B.C. Women's Hospital & Health Centre
2023-2025
World Health Organization - Uganda
2022-2024
Children's & Women's Health Centre of British Columbia
2024
Mbarara University of Science and Technology
2013-2023
Women's Hospital
2023
St. Jude Children's Research Hospital
2022
The University of Queensland
2021
Kenya Medical Research Institute
2021
Medication-related visits to the emergency department are an important but poorly understood phenomenon. We sought evaluate frequency, severity and preventability of drug-related department.
Importance Sepsis is a leading cause of death among children worldwide. Current pediatric-specific criteria for sepsis were published in 2005 based on expert opinion. In 2016, the Third International Consensus Definitions and Septic Shock (Sepsis-3) defined as life-threatening organ dysfunction caused by dysregulated host response to infection, but it excluded children. Objective To update evaluate septic shock Evidence Review The Society Critical Care Medicine (SCCM) convened task force 35...
Importance The Society of Critical Care Medicine Pediatric Sepsis Definition Task Force sought to develop and validate new clinical criteria for pediatric sepsis septic shock using measures organ dysfunction through a data-driven approach. Objective To derive novel across differently resourced settings. Design, Setting, Participants Multicenter, international, retrospective cohort study in 10 health systems the US, Colombia, Bangladesh, China, Kenya, 3 which were used as external validation...
Objective Anaemia affects the majority of children in sub-Saharan Africa (SSA). Previous studies risk factors for anaemia have been limited by sample size, geography and association many with poverty. In order to measure relative impact individual, maternal household young children, we analysed data from all SSA countries that performed haemoglobin (Hb) testing Demographic Health Surveys. Design setting This cross-sectional study pooled household-level most recent Surveys conducted 27...
Sepsis represents the progressive underlying inflammatory pathway secondary to any infectious illness, and ultimately is responsible for most disease-related deaths. Addressing issues related sepsis has been recognized as an important step towards reducing morbidity mortality in developing countries, where majority of 7.5 million annual deaths children under 5 years age are considered be sepsis. However, despite its prevalence, largely neglected. Application definitions created use...
To derive a model of paediatric postdischarge mortality following acute infectious illness.
Abstract Endometrial cancer (EC) has four molecular subtypes with strong prognostic value and therapeutic implications. The most common subtype (NSMP; No Specific Molecular Profile) is assigned after exclusion of the defining features other three includes patients heterogeneous clinical outcomes. In this study, we employ artificial intelligence (AI)-powered histopathology image analysis to differentiate between p53abn NSMP EC consequently identify a sub-group that markedly inferior...
Adverse drug events (ADEs) are unintended and harmful consequences of medication use. They associated with high health resource use cost. Yet, levels inaccuracy exist in their identification clinical practice, over one-third remaining unidentified the emergency department (ED). The study objective was to derive decision rules (CDRs) that sensitive for detection ADEs, allowing systematic early a patient's hospital course.This prospective observational cohort carried out two Canadian tertiary...
Pneumonia is the leading cause of death in children globally. In low- and middle-income countries (LMICs) pneumonia diagnosis relies on accurate assessment respiratory rate, which can be unreliable when completed by nurses with less-advanced training. To inform more measurements, we investigate repeatability RRate app used Ugandan district hospitals. This secondary analysis included 3,679 aged 0–5 years. The dataset had two sequential measurements rate collected 14 using app. We measured...