Zhongyao Li

ORCID: 0000-0002-3295-7718
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About
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Research Areas
  • Graphene research and applications
  • Amyotrophic Lateral Sclerosis Research
  • 2D Materials and Applications
  • Topological Materials and Phenomena
  • Neurogenetic and Muscular Disorders Research
  • Quantum and electron transport phenomena
  • MXene and MAX Phase Materials
  • Parkinson's Disease Mechanisms and Treatments
  • Nerve injury and regeneration
  • Advancements in Battery Materials
  • Liver Disease Diagnosis and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Fibroblast Growth Factor Research
  • Magnetic properties of thin films
  • Physics of Superconductivity and Magnetism
  • Diet and metabolism studies
  • Nutritional Studies and Diet
  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • Diet, Metabolism, and Disease
  • Superconducting Materials and Applications
  • Nutrition and Health in Aging
  • Neurogenesis and neuroplasticity mechanisms
  • Muscle Physiology and Disorders
  • Adipose Tissue and Metabolism

Pediatrics and Genetics
2025

University of Shanghai for Science and Technology
2015-2024

Hebei Medical University
2014-2024

Second Hospital of Hebei Medical University
2014-2024

Chinese PLA General Hospital
2024

Nanjing University of Science and Technology
2024

Tufts University
2024

PLA Academy of Military Science
2024

Fudan University
2007-2023

Yale University
2021-2023

An equivalent circuit grid (ECG) model is proposed to analyse the time-varying characteristics of no-insulation (NI) ReBCO pancake coils. In model, each turn coil subdivided into fine elements in azimuthal direction, and element a parameter. Then, grid. A math based on Kirchhoff's law solve model. The distribution electrical current inside NI analysed for charging discharging process. finite method (FEM) coupled calculate magnetic field induced by coil. To validate double (DP) fabricated...

10.1088/0953-2048/28/4/045017 article EN Superconductor Science and Technology 2015-03-13

The electronic structures of graphene-MoS2 heterojunction under tension and external electric field were examined on the basis density-functional theory. MoS2 changes hybrid structure from semiconductor to metal. transition is sensitive dependence bandgap lattice constant. vertical has little influence MoS2, while it can also adjust charge transfer between monolayer graphene. In addition, Schottky barrier linearly dependent intensity with an effective vacuum spacing 1.3 Å. It discussed in...

10.1021/acs.jpclett.5b01233 article EN The Journal of Physical Chemistry Letters 2015-08-04

During a short period of time, the outbreak pneumonia caused by novel coronavirus, named Novel Coronavirus Pneumonia (NCP), was first reported in China, spreading to 24 countries and regions rapidly. The number confirmed cases deaths continued rise. World Health Organization (WHO) announced that outbreaks coronavirus have constituted Public Emergency International Concern. Efficient infection control can prevent virus from further spreading, which makes epidemic situation under control. Due...

10.3760/cma.j.issn.1002-0098.2020.0001 article EN PubMed 2020-02-14

Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common form of and often precursor for more serious conditions such as nonalcoholic steatohepatitis cirrhosis. Although gut microbiome has been implicated in development NAFLD, strong association obesity with NAFLD its effect on structure made interpreting study outcomes difficult. In present study, we examined taxonomic functional differences between microbiomes youth without NAFLD. Shotgun metagenome sequencing was performed to...

10.1002/hep4.1944 article EN cc-by-nc-nd Hepatology Communications 2022-03-28

Haploinsufficiency of the protein kinase Tbk1 has shown to cause both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD); however, pathogenic mechanisms are unclear. Here we show that conditional neuronal deletion in leads cognitive locomotor deficits mice. Tbk1-NKO mice exhibited numerous neuropathological changes, including neurofibrillary tangles, abnormal dendrites, reduced dendritic spine density, cortical synapse loss. The Purkinje cell layer cerebellum presented...

10.18632/aging.101936 article EN cc-by Aging 2019-04-30

Growth differentiation factor 15 (GDF15) has been associated with food intake and weight regulation in response to metabolic stress. In animal models, it noted that may play a role the progression of non-alcoholic fatty liver disease (NAFLD), leading cause chronic children.In current study, we explored association circulating plasma concentrations GDF15 NAFLD youth overweight/obesity, whether changes parallel intrahepatic fat content (HFF%) over time.Plasma were measured by ELISA 175...

10.1038/s41387-022-00187-2 article EN cc-by Nutrition and Diabetes 2022-02-22

BACKGROUND. This study examined the underlying cellular mechanisms associated with insulin resistance (IR) and metabolic disease risk within subcutaneous adipose tissue (SAT) in youth obesity IR compared those without IR.

10.1172/jci184740 article EN cc-by Journal of Clinical Investigation 2025-03-16

Abstract Aberrant microglial activation and neuroinflammation is a pathological hallmark of amyotrophic lateral sclerosis (ALS). Fractalkine (CX3CL1) mostly expressed on neuronal cells. The fractalkine receptor (CX3CR1) predominantly microglia. Many progressive neuroinflammatory disorders show disruption the CX3CL1/CX3CR1 communication system. But exact role in ALS pathology remains unknown. F1 nontransgenic/CX3CR1 +/− females were bred with SOD1 G93A /CX3CR1 males to produce F2 −/− , +/+ ....

10.1515/hsz-2018-0204 article EN Biological Chemistry 2018-10-23

Substrate-induced spin–orbit splitting in graphene on Ni, Au and Ag(111) is examined the basis of density-functional theory. The Rashba π bands along ΓM direction surface Brillouin zone Ni(111) found to be very small (a few millielectronvolts), consistent with experimental report Rader et al. Instead, strong (near 100 meV) can obtained for a certain stretch distortion substrate. It ascribed effective match energy between C 2p 5d bands, from analysis densities states. net charge transfer...

10.1088/0953-8984/23/22/225502 article EN Journal of Physics Condensed Matter 2011-05-17

Effects of binding modes and anchoring groups on nonequilibrium electronic transport properties alkane molecular wires are investigated from atomic first-principles based density functional theory Green’s function formalism. Four typical modes, top, bridge, hcp-hollow, fcc-hollow, considered at one the two contacts. For with three different groups, dithiol, diamine, or dicarboxylic acid, low bias conductances resulting four all found to have either a high value, well consistent recent...

10.1063/1.3276280 article EN The Journal of Chemical Physics 2009-12-28
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