A5100359996- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- RNA modifications and cancer
- Genetic Mapping and Diversity in Plants and Animals
- Ubiquitin and proteasome pathways
- Cancer, Lipids, and Metabolism
- Plant Disease Resistance and Genetics
- Dendrimers and Hyperbranched Polymers
- Ferroptosis and cancer prognosis
- RNA Interference and Gene Delivery
- Proteoglycans and glycosaminoglycans research
- Cancer Treatment and Pharmacology
- Ginseng Biological Effects and Applications
- Genomics and Phylogenetic Studies
- Myasthenia Gravis and Thymoma
- Cancer-related gene regulation
- Cell death mechanisms and regulation
- Mycobacterium research and diagnosis
- Cancer, Hypoxia, and Metabolism
- RNA Research and Splicing
- Cancer Cells and Metastasis
- Galectins and Cancer Biology
Nanjing Drum Tower Hospital
2012-2024
State Key Laboratory of Biotherapy
2020
Sichuan University
2020
Linyi People's Hospital
2019
First Affiliated Hospital of Henan University of Science and Technology
2019
Luoyang Institute of Science and Technology
2019
Shanghai Pulmonary Hospital
2013
Tongji University
2013
Huzhou Central Hospital
2012
Wannan Medical College
2012
Malignant gliomas are the most common and deadly primary brain tumors in adults. Increasing evidence has indicated that microRNAs (miRNAs) have an influence on regulation of apoptotic cell signaling. Downregulation miRNA 218 (miR-218) been human glioma specimens. Here, we investigate function miR-218 apoptosis tumor growth cells. The expression was detected by real-time quantitative reverse transcriptase PCR. effects proliferation tumorigenicity were investigated vitro clonogenicity vivo...
Although recent evidence shows that long noncoding RNAs (lncRNAs) are involved in the regulation of gene expression and cancer progression, understanding role lncRNAs lung metastasis is still limited. To identify novel non-small cell (NSCLC), we profile NSCLC tumor matched normal samples using GeneChip® Human Gene 2.0 ST Array, which provides most accurate, sensitive, comprehensive measurement protein coding lncRNA transcripts. We identified a panel key factors dysregulated cancer. Among...
Abstract Long noncoding RNAs (lncRNAs) have been implicated in the regulation of resistance to radiotherapy cervical cancer, which is a type gynecological disease with high mortality women around world. Hence, our purpose delineate involvement LINC00958 regulating cell sensitivity cancer. expression cancer was assayed, followed by verification relationship among LINC00958, microRNA‐5095 (miR‐5095) and ribonucleotide reductase subunit M2 (RRM2). Hela cells were transduced up‐/downregulation...
Abstract The therapeutic approach to thymic cysts remains a subject of controversy. Predicted biomarkers for identifying and thymoma (THYM) are crucial. In this research, patients diagnosed with (MTC, n = 6) (B1, 6; B3, were enrolled. Proteins superior quality subjected TMT labeling UPLC-MS, differentially expressed proteins (DEPs) identified. Gene Ontology (GO), Kyoto Encyclopedia Genes Genomes (KEGG), protein-protein interactive network analyses applied the DEPs. Some key genes(DEGs)...
Lung adenocarcinoma is the most common subtype of non-small cell lung cancer, and platelet receptor-related genes are related to its occurrence progression. A new prognostic indicator based on was developed with multivariate COX analysis. Prognostic markers platelet-related risk score perform moderately in prognosis prediction. The functional annotation this model high-risk patients shows that pathways cycle, glycolysis platelet-derived factors rich. It worth noting somatic mutation analysis...
Long non-coding RNA OIP5-AS1 (lncRNA OIP5-AS1) plays a significant role in ox-LDL induced inflammation.
Non-small cell lung cancer (NSCLC), accounts for approximately 80-85% of all cases, is the most common cause cancer-related death worldwide. With advances high-throughput sequencing, accumulating evidence suggested that long non-coding RNA molecules, with transcripts larger than 200 nucleotides, have important roles in multiple biological processes NSCLC. In this review, we will highlight emerging RNAs (lncRNAs) NSCLC, discussing both onco-lncRNAs and tum
Lung cancer is the leading cause of cancer-related death worldwide. Overall survival all stages unsatisfactory due to high metastasis and recurrence rates. Recent studies indicated that epithelial-to-mesenchymal transition (EMT) involved in progression cancer. Some reports also indicate HS3ST3B1 angiogenesis proliferation cells. However, its role non-small cell lung (NSCLC) not well known. In this study, we found was significantly up-regulated NSCLC tissues compared with matched normal...
Abstract As a serious malignancy with high incidence and fatality, non-small cell lung cancer (NSCLC) has affected millions of people each year worldwide. However, the 5-year survival rate NSCLC is still not satisfactory. Therefore, it particularly imperative necessary to explore underlying molecular mechanisms contribute potential therapeutic targets strategies. Six clinical samples including three normal tissues obtained from patients diagnosed were sequenced through Illumina Hiseq2500...