A5009362817- Orthodontics and Dentofacial Orthopedics
- Dental materials and restorations
- Bone Metabolism and Diseases
- dental development and anomalies
- Temporomandibular Joint Disorders
- Dental Implant Techniques and Outcomes
- Osteoarthritis Treatment and Mechanisms
- Endodontics and Root Canal Treatments
- Proteoglycans and glycosaminoglycans research
- Bone health and treatments
- Cell Adhesion Molecules Research
- Bone and Dental Protein Studies
- Dental Radiography and Imaging
- Dental Erosion and Treatment
- Bone Tissue Engineering Materials
- Connective tissue disorders research
- Cellular transport and secretion
- Dental Research and COVID-19
- Periodontal Regeneration and Treatments
- Titanium Alloys Microstructure and Properties
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Welding Techniques and Residual Stresses
- Dental Trauma and Treatments
- Immune Response and Inflammation
Tohoku University
1995-2024
Hokkaido University
2022
Health Sciences University of Hokkaido
2009-2018
GTx (United States)
1997
Osteoimmunology peeks into the interaction of bone and immune system, which has largely proved to be a multiplex reaction. Osteocytes have been shown regulate resorption through expression RANKL in physiologic pathologic conditions. TNF-α, product is an important cytokine regulating inflammatory conditions either directly or by increasing M-CSF expressions osteoblasts stromal cells. The effect TNF-α on wide range cell types documented; however, direct osteocytes not established yet. In this...
To measure the forces delivered by thermoplastic appliances made from three materials and investigate effects of mechanical properties, material thickness, amount activation on orthodontic forces.Three materials, Duran (Scheu Dental), Erkodur (Erkodent Erich Kopp GmbH), Hardcast with two different thicknesses were selected. Values elastic modulus hardness obtained nanoindentation measurements at 28°C. A custom-fabricated system a force sensor was employed to obtain in vitro for 0.5-mm 1.0-mm...
We compared the accuracy of digital models generated by desktop-scanning conventional impression/plaster versus intraoral scanning. Eight ceramic spheres were attached to buccal molar regions dental epoxy models, and reference linear-distance measurement determined using a contact-type coordinate measuring instrument. Alginate (AI group) silicone (SI impressions taken converted into cast stone; scanned desktop scanner. As an alternative, scans scanner, from these (IOS group). Twelve...
Mandibular condylar cartilage is the center of greatest growth in craniofacial complex, and associated with maxillofacial skeleton morphogenesis temporomandibular joint function. The process grows a wide range directions from anterosuperior to posterior, resulting highly diverse mandibular morphology. Condylar direction closely related displacement vertical jaw deviations (i.e., high or low angle). cartilage, which ontogenetically designated secondary differs other primary (e.g., articular...
To determine the effect of coating on properties two esthetic orthodontic nickel-titanium wires.Woowa (polymer coating; Dany Harvest) and BioForce High Aesthetic Archwire (metal Dentsply GAC) with cross-section dimensions 0.016 × 0.022 inches were selected. Noncoated posterior regions anterior-coated Woowa uncoated Sentalloy used for comparison. Nominal compositions determined by x-ray fluorescence (JSX-3200, JOEL). Cross-sectioned external surfaces observed a scanning electron microscope...
Matrix metalloproteinases (MMPs) 8 and 13 comprise the collagenase subfamily in rats mice, only MMP13 has been implicated degradation of collagenous matrices during development bone cartilage. On hypothesis that MMP8 is also involved cartilage development, present study was designed to investigate gene expression rat embryonic mandibles hind limbs. Expression examined with situ hybridization RT-PCR compared MMP13. Osteoblastic chondrocytic cells expressing matrix molecules were identified...
Interleukin (IL)-33 is a member of the IL-1 family, which acts as an alarmin. Several studies suggested that IL-33 inhibited osteoclastogenesis and bone resorption. Tumor necrosis factor-α (TNF-α) considered direct inducer osteoclastogenesis. However, there has been no report regarding effect on TNF-α-induced The objective this study to investigate role In in vitro analysis osteoclastogenesis, osteoclast precursors, were derived from marrow cells, treated with or without presence TNF-α....
Abstract Apical periodontitis (AP) is an acute or chronic inflammatory disease caused by complex interactions between infected root canal and host immune system. It results in the induction of mediators such as chemokines cytokines leading to periapical tissue destruction. To understand molecular pathogenesis AP, we have investigated inflammatory-related genes that regulate AP development. We found here macrophage-derived CXCL9, which acts through CXCR3, recruited progressed AP. The...
The effects of 2 years storage and 6000 thermocycles on the shear bond strength (SBS) two self-etching adhesive systems were studied. Two primer (SEP) (Transbond Plus Beauty Ortho Bond) one etch rinse system XT) used to brackets 126 human premolars that then stored in artificial saliva for 24 hours or thermocycled distilled water before SBS testing with a universal machine. remnant index (ARI) scores calculated. Data compared by two-way analysis variance chi-square analysis. Enamel/adhesive...
To test the hypothesis that a diamond-like carbon coating does not affect frictional properties of orthodontic wires.Two types wires (nickel-titanium and stainless steel) were used, (DLC) films deposited on wires. Three brackets, conventional steel bracket two self-ligating used for measuring static friction. DLC layers observed by three-dimensional scanning electron microscopy (3D-SEM), surface roughness was measured. Hardness elastic modulus obtained nanoindentation testing. Frictional...
To investigate the effects of temperature changes and stress loading on mechanical shape memory properties thermoplastic materials with different glass transition behaviours crystal structures. Five materials, polyethylene terephthalate glycol (Duran®, Scheu Dental), polypropylene (Hardcast®, polyurethane (SMP MM®, SMP Technologies) three temperatures ( Tg ) were selected. The structure assessed using differential scanning calorimetry X-ray diffraction. deterioration by thermal cycling...
Docosahexaenoic acid (DHA) is an n-3 fatty that important structural component of the cell membrane. DHA exerts potent anti-inflammatory effects through G protein-coupled receptor 120 (GPR120), which a functional for acids. also regulates osteoclast formation and function. However, no studies have investigated effect on inflammation-induced in vivo. In present study, we whether influences formation, bone resorption expression osteoclast-associated cytokines during lipopolysaccharide...