A5059944302- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Lipoproteins and Cardiovascular Health
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Acute Myocardial Infarction Research
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac pacing and defibrillation studies
- Cardiovascular Health and Disease Prevention
- Antiplatelet Therapy and Cardiovascular Diseases
- Hormonal Regulation and Hypertension
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Hemodynamic Monitoring and Therapy
- Long-Term Effects of COVID-19
- Cardiovascular and exercise physiology
- COVID-19 and healthcare impacts
- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Chronic Disease Management Strategies
- Peripheral Artery Disease Management
- Global Public Health Policies and Epidemiology
Azienda Ospedaliera San Giovanni Addolorata
2016-2025
Istituto Superiore di Sanità
2023
Regional Health
2023
University of Health Sciences
2023
Associazione Nazionale Medici Cardiologi Ospedalieri
2008-2017
Italian Association for Cancer Research
2017
National School of Public Health
2013
Mario Negri Institute for Pharmacological Research
2012
Community Hospital
2011-2012
October 6 University
2010
Abstract —The development of the left ventricle parallels body growth. During infancy, relation between size and ventricular (LV) mass is very close. With advancing age, variability LV in to markedly increases. To test hypothesis that age-related increase due progressive impact hemodynamic stimuli on growth, quantitative M-mode echocardiograms were obtained 766 normal-weight, normotensive individuals over a range ages from 1 day 85 years (330 female subjects, 373 subjects younger than 18...
Background/Objectives: This study assessed the proportion of secondary cardiovascular prevention patients who achieved low-density lipoprotein (LDL) cholesterol targets as per 2019 ESC/EAS Dyslipidemia Guidelines. We also evaluated whether lipid-lowering therapies (LLTs) were adjusted in not meeting and analyzed likelihood these modifications achieving recommended levels. Methods: A multicenter, cross-sectional observational retrospectively reviewed medical records 1909 outpatients 9 Italian...
OBJECTIVE--To identify the characteristics of cardiac involvement in self-induced starvation phase anorexia nervosa. METHODS--Doppler echocardiographic indices left ventricular geometry, function, and filling were examined 21 white women (mean (SD) 22 (5) years) with nervosa according to DSMIII (Diagnostic Statistical Manual Mental Disorders) criteria, 19 (23 (2) normal weight, constitutionally thin (21 (4) body mass index < 20. RESULTS--13 patients (62%) had abnormalities mitral valve...
Arterial hypertension determines distinct adaptive left ventricular geometric responses, which may differently affect function and atrial performance.In this study, the effect of geometry on size function, relationship between mass were assessed in 336 patients with systemic arterial who had undergone Doppler echocardiography.Patients classified into concentric (110 defined as relative wall thickness > or = 0.44) eccentric groups (226 < 0.44). Comparison to latter, former greater size,...
The hospital discharge is often poorly standardized and affected by discontinuity fragmentation of care, putting patients at high risk both post-discharge adverse events early readmission. present ANMCO document reviews the modifiable components process related to or re-hospitalizations suggests optimal methods for redesigning whole process. key principles proper transfer care acknowledge that discharge: • not an isolated event, but a has be planned as soon possible after admission, ensuring...
Abstract Background Although sex differences in cardiovascular diseases are recognised, including incidence, clinical presentation, response to treatments, and outcomes, most of the practice guidelines not sex-specific. Heart failure (HF) is a major public health challenge, with high care expenditures, prevalence, poor outcomes. The objective was analyse sex-specific association socio-demographics, life-style factors characteristics prevalence HF diastolic left ventricular dysfunction (DLVD)...
Heart failure is the leading cardiovascular cause of hospitalization with an increasing prevalence, especially in older patients. About 50% patients heart have preserved ventricular function, a form that, until few years ago, was orphaned by pharmacological treatments effective reducing and mortality. New trials, which tested use gliflozins ejection fraction (HFpEF), for first time demonstrated their effectiveness changing natural history this insidious frequent failure. Therefore,...
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the cornerstone of pharmacologic management patients acute coronary syndrome (ACS) and/or those receiving stents. Long-term (>1 year) DAPT may further reduce risk stent thrombosis after percutaneous intervention (PCI) decrease occurrence non-stent-related ischaemic events in ACS. Nevertheless, compared alone, extended use plus increase bleeding that have been strongly linked to adverse outcomes including...
The ongoing COVID-19 pandemic spreading all around the world has stressed over its capabilities and determined profound changes in health systems countries caused hundreds of thousand deaths. Health professionals have been called to a tremendous effort deal with this emergency, often contaminating or succumbing themselves disease.
The COVID-19 outbreak is having a significant impact on both cardiac rehabilitation (CR) inpatient and outpatient healthcare organization. variety of clinical care scenarios we are observing in Italy depends the region, organization local services hospital involved. Some wards have been closed to make room dedicated beds or quarantine exposed health personnel. In other cases, CR units converted transformed into units. present document aims at defining state art during pandemic, through...
To evaluate whether assessment of appropriateness left ventricular mass (LVM) adds to the traditional definition hypertrophy (LVH).Cross-sectional, relational.Echocardiographic LVH and LVM were studied in 562 subjects (231 normotensive controls, aged 35+/-11 years, 142 women; 331 hypertensive patients, 47+/-11 135 women) classified on basis either presence or absence both (LVM index > = 51 g/m2.7) inappropriate 128% value predicted by an equation including age, sex stroke work).Body was...
Whether left ventricular (LV) systolic function differs between healthy men and women independent of afterload, LV geometry, age, heart rate body size is disputed.We studied 517 clinically adults without history cardiovascular or endocrinal disease (age range 20-70, 274 with essential arterial hypertension). Echocardiography was used to assess geometry both at endocardial midwall levels.Normotensive hypertensive had higher levels afterload. After adjustment for surface area, remained in than...
We assessed the relations of left ventricular filling to load and geometry by Doppler echocardiography in 80 normotensive subjects (40 normal-weight [36±12 years, 24 women] 40 obese [35±13 women]) 61 hypertensive without silent coronary heart disease (29 [43±13 15 32 [42±13 19 comparable midwall performance. Left mass divided height 2.7 power was higher all groups than (all P <.0001) ( <.001). After controlling for age, sex, blood pressure, rate, isovolumic relaxation time prolonged...
For quantitative assessment of cardiac autonomic control, time and frequency domain measures heart period variability were calculated by 24 h Holter recording in 10 young obese women with early-onset familial obesity control subjects. Ultra low very power lower subjects than controls (P < 0.05). High power, a pure measure vagal tone, was comparable between the two groups. However, which analysed over reflects parasympathetic more sympathetic activity, slightly = 0.06). Body mass index showed...
The evaluation of the effect obesity on left ventricular systolic performance may differ in relation to method used measure function and type study population. Whether worsens midwall mechanics arterial hypertension has never been investigated. Accordingly, we assessed echocardiographic shortening-circumferential end-systolic stress relations 156 normotensive normal-weight (reference) adults, 94 overweight (1985 National Institutes Health partition values) obese (body mass index > 30 kg/m2)...
Our aim was to assess echocardiographic parameters and the effort blood pressure of 50 children hypertensives with respect normotensives. Systolic diastolic pressures at rest were comparable between two groups. Left ventricular mass index (LVMI), interventricular septum posterior wall thicknesses higher in (P < 0.01). maximal until 5 min recovery Similarly, 1 2 Direct correlations mean thickness (r = 0.39, P 0.01) LVMI 0.33, 0.05) percentage systolic increases found but not In conclusion, we...
Fibroblast growth factor-23 (FGF-23) and vitamin D are hormones involved in phosphate homoeostasis. They also directly influence cardiomyocyte hypertrophy. We examined whether the relationships between levels of or FGF-23, cardiac phenotype outcome were independent established biomarkers a large cohort community-dwelling elderly subjects.Plasma FGF-23 measured 1851 men women (65-84 years) resident Lazio region Italy. Participants referred to eight cardiology centres for clinical examination,...
AimsAccording to recent data, more accurate selection of patients undergoing coronary angiography for suspected artery disease (CAD) is needed. From the Active PREvention Study multicentre prospective study, we further analyse whether carotid intima–media thickness (cIMT), plaques (cPL), and echocardiographic cardiac calcium score (eCS) have incremental discriminatory reclassification predictive value CAD over clinical risk in subjects angiography, specifically depending on their low,...