A5101407525- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Boron Compounds in Chemistry
- Boron and Carbon Nanomaterials Research
- Magnetism in coordination complexes
- Supramolecular Chemistry and Complexes
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Inorganic Chemistry and Materials
- Nuclear Materials and Properties
- Crystallography and molecular interactions
- Cyclopropane Reaction Mechanisms
- Metal and Thin Film Mechanics
- Metal-Organic Frameworks: Synthesis and Applications
- Lung Cancer Diagnosis and Treatment
- Microfluidic and Capillary Electrophoresis Applications
- Cultural Differences and Values
- Organic and Molecular Conductors Research
- Healthcare professionals’ stress and burnout
- Analytical Chemistry and Chromatography
- Catalytic Alkyne Reactions
- Liver physiology and pathology
- Trace Elements in Health
- Chemical Synthesis and Characterization
- Service and Product Innovation
- Catalytic Cross-Coupling Reactions
Shanghai Institute of Materia Medica
2025
Chinese Academy of Sciences
2025
East China University of Science and Technology
2024
Second Affiliated Hospital of Zhejiang University
2024
Tris Pharma (United States)
2024
Novartis (United States)
2024
Renmin University of China
2014-2023
Nanjing University
1999-2022
Government of Jiangsu Province
2020-2022
Detection Limit (United States)
2020
MET proto-oncogene (MET) alterations are known driver oncogenes in non-small cell lung cancer (NSCLC).Since the identification of as a potential therapeutic target, extensive clinical trials have been performed.As result, MET-targeted therapies, including tyrosine kinase inhibitors, monoclonal antibodies, and antibodydrug conjugates, now play important roles standard treatment MET-altered NSCLC; they considerably improved outcomes patients with tumors that harbor oncogenic drivers.Although...
The C(sp2)-C(sp3) cross-coupling reaction is an effective way to increase the C(sp3) content in compound collections for drug discovery, enhancing molecular diversity and offering a unique chemistry starting point. In this study, we report mild, DNA-compatible, off-DNA-inert photochemical inspired by amino radical transfer strategy. This method demonstrates broad substrate scopes DNA-encoded library (DEL) constructions, utilizing commonly available structures on DNA diverse alkyl boronate...
The theory of value cocreation has been applied widely in the research a lot fields, including field travelling. At present, online shared cars have become one main modes travel for urban residents, which caused people to think about quality its service and customer satisfaction. objective this is explore impact by both platform drivers on satisfaction user loyalty using Didi as an example. We propose five factors that can measure behaviors, among system availability privacy count perceived...
The study aimed at investigating the state of psychiatric nurses' job satisfaction, burnout, and moderating effect family support between them in China during COVID-19 pandemic.Online self-report questionnaires were distributed 212 nurses participated research. Pearson correlation analysis, multiple stepwise regression simple slope test used for data analysis.The results showed that status their satisfaction (53.67 ± 10.72) burnout (33.62 13.84) did not reach a satisfactory level had...
A series of axially chiral bis-1,2,3-triazol-5-ylidene Au(I) complexes (R)-8a–g and one mono-1,2,3-triazol-5-ylidene complex (R)-9a were prepared from commercially available (R)-binaphthyl-2,2-diamine (BINAM) compound, in which, transmetalation bis(MIC)-bis[Ag(I)] intermediates to the corresponding employed as key synthetic step. The structures these MIC–Au(I) diversified by using different alkyne reagents copper catalyzed azide–alkyne cycloaddition (CAAC) Three Ag(I) complexes, (R)-7a,...
A new type of blue emitter, N²-Indolyl-1,2,3-triazoles (NITs), with the λmax ranging from 420-480 nm and Stokes shift 89-143 nm, were synthesized through coupling reaction indoles triazole derivatives. The influence different substitution patterns on optical properties (efficiency, excitation, emission wavelengths) NITs was investigated. In addition, one palladium complex by using as ligands, which, however, exhibited no fluorescent activity, but did show enhanced co-planarity. Lastly, two...
A series of novel tripyrazolate linked metallomacrocycles and cages possessing different shapes were constructed by dimetal-coordination motifs in aqueous solution.
ABSTRACT The high hydrophobicity and chemical inertness of poly(styrene‐divinylbenzene) (PS‐DVB) microspheres make their surface hydrophilic modification difficult. Here we describe a facile way to convert PS‐DVB hydrophilic, then can be used as polar stationary phase for interaction chromatography. This approach utilizes the grafting an acrylamide‐terminated lysine zwitterionic monomer onto via free radical polymerization. obtained shows good hydrophilicity typical retention mechanism...
A linear triple-helical supramolecule Ni9L6 has been prepared through a controllable self-assembly approach using 1,3-bis-(3-oxo-3-phenylpropionyl)-2-hydroxy-5-methylbenzene (H3L) and Ni(OAc)2 under solvothermal conditions. Single-crystal X-ray diffraction analysis confirms the axial C3 symmetrical helical structure of product temperature-dependent magnetic susceptibility corresponds to typical shape paramagnet showing dominant ferromagnetic exchange couplings between neighboring NiII ions.
Virtual Doctor aims to make healthcare more available worldwide by using image classification detect diseases from pictures. represents a ground-breaking initiative aimed at transforming health assessments worldwide, particularly in areas where resources are scarce. Utilizing sophisticated machine learning model, this platform allows users perform real-time evaluations simply capturing images smartphone or other camera-equipped mobile devices. empowers individuals conduct selfassessments and...
In this paper, we evaluate the influence of Quantum Confinement and Coulomb Blockade on retention characteristics charge trapping memory with incorporating Si nanocrystals into layer using self-consistent simulator developed. The effects under different trap densities, temperatures, nanocrystal sizes tunneling oxide thicknesses are analyzed comprehensively. results can be used to study performance mechanisms based memory.