A5082387128- Hydrogen's biological and therapeutic effects
- Renal cell carcinoma treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- MRI in cancer diagnosis
- Cancer Genomics and Diagnostics
- Central Venous Catheters and Hemodialysis
- Microbial Inactivation Methods
- Renal and Vascular Pathologies
- RNA modifications and cancer
- Effects of Radiation Exposure
- Polyomavirus and related diseases
- Vascular anomalies and interventions
- Management of metastatic bone disease
- Cancer-related Molecular Pathways
- Cerebrospinal fluid and hydrocephalus
- Ubiquitin and proteasome pathways
- Cancer Cells and Metastasis
- Chemical Reactions and Isotopes
- Hydrogen Storage and Materials
- Liver physiology and pathology
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Lung Cancer Diagnosis and Treatment
Shenzhen Second People's Hospital
2018-2025
Shenzhen University Health Science Center
2020-2022
Iowa Digestive Disease Center
2010
Peking University Shenzhen Hospital
2008
Peking University First Hospital
2007
Peking University
2007
Next-generation sequencing (NGS) is an efficient and sensitive method to detect mutations from ctDNA. Many features clinical conditions could significantly affect the concordance between ctDNA corresponding tumor tissues. Our goal was systematically investigate critical factors contributing different tissues.We recruited two groups of IIIB or IV lung cancer patients: The standard group evaluate accuracy our tissues, study with various conditions. We applied unique identification (UID)...
This study aimed to investigate the safety and short-term efficacy of irreversible electroporation (IRE) combined with allogenic natural killer (NK) cell immunotherapy in treatment patients unresectable primary liver cancer. Between October 2015 December 2016, 40 were enrolled randomly allocated either IRE group (n = 22) or IRE–NK 18). All adverse events experienced by recorded; changes tumor biomarkers [AFP, CA 19-9, circulating cells (CTCs)], lymphocyte number function, quality life,...
Background/Aims: Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed at an advanced stage, resulting in extremely poor 5-year survival. Late diagnosis of PDAC mainly due to lack a reliable method early detection. Carbohydrate antigen (CA) 19-9 used as tumor biomarker PDAC; however, the test lacks sensitivity and specificity. Therefore, new sensitive minimally invasive diagnostic tools are required detect pancreatic cancer. Methods: Here, we investigated circulating DNA (ctDNA) which...
We present the case of a 72-year-old female patient with gallbladder cancer (GBC) who developed in situ recurrence and liver metastases 9 mo after irreversible electroporation ablation oral tegafur (a fluoropyrimidine derivative) chemotherapy, which failed to control progression disease. The further lymph nodes around head pancreas. had severe anemia, requiring weekly blood transfusions. tumor invaded descending part duodenum, causing intestinal leakage hepatic colonic adhesion.The refused...
Rationale: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver that leading cause cancer-related mortality worldwide.However, genetic alterations and mechanisms underlying HCC development remain unclear.Methods: Tissue specimens were used to evaluate expression DEAD-Box 56 (DDX56) determine its prognostic value.Colony formation, CCK8, EdU-labelling assays performed assess effects DDX56 on proliferation.The in vivo role was evaluated using mouse orthotopic xenograft...
Lung cancer is the most common type of tumor, prone to contralateral lung, bone and brain metastasis. We report a 44-year-old woman diagnosed with lung multiple metastases in November 2015. Oral targeted drugs were initiated after removal metastases, lesions remained stable for 28 months. In March 2018, intracranial as well hydrocephalus accumulation third ventricle lateral ventricles, bone, adrenal gland, liver noted. Hydrogen-gas monotherapy was started control tumor month later. After 4...
Hydrogen therapy has been reported to convert exhausted programmed cell death receptor (PD-1)+CD8+ T cells PD-1-CD8+ cells, in advanced colorectal cancer patients, which is associated with significantly prolonged survival.A 72-year-old female patient presented metastatic gallbladder and underwent symptomatic treatment combined hydrogen therapy. The tumors were initially enlarged displayed increased tumor marker expression following inhalation therapy, after they continued remit, similar the...
Abstract: Three patients with nasopharyngeal carcinoma developed binaural secretory otitis media 12, 2, and 0.5 years after radiotherapy, respectively. The secretions subsided conventional drug drainage treatments, but hearing continued to deteriorate until severe loss was documented in both ears. After examination of the eardrum tympanum, were enrolled a clinical trial first half 2019 (ClinicalTrials.gov: NCT03818347). 0.5, 1 2 months continuous hydrogen–oxygen therapy, our three reported...
The cause of idiopathic normal pressure hydrocephalus's (iNPH) clinical symptoms remains unclear. cerebral cortex is the center brain and provides a structural basis for complex perception motor function. This study aimed to explore relationship between changes in volume patients with iNPH. included 21 iNPH 20 aging (NA) controls. Voxel-based morphometry statistical results showed that, compared NA, gray matter volumes bilateral temporal lobe, hippocampus, thalamus, insula, left amygdala,...
This study aims to the preparation method of arsenic trioxide (As2O3) polylactic-co-glyconlic acid (PLGA) microspheres and 10-hydroxycamptothecin (HCPT) PLGA explore their therapeutic effects as embolic agents for VX2 hepatocellular carcinoma in rabbits.As2O3 HCPT were prepared by multiple emulsion solvent evaporation method. Scanning electron microscopy (SEM) particle size distribution used analyze morphology, drug sustained release ability was observed vitro. The rabbit model established...
Objective To compare of the clinical using effect implantable venous-access port(VAP)among different methods and postoperative complication. Methods From 2011 to 2014,a total 359 patients with VAP were included in this study.All divided into two groups according surgery approaches methods, 307 cases implanted through internal jugular vein,and other 52 subclavian vein intubation. Statistics flow conditions complication between gathered compared. Results There 3 infected,and 13...
Implanted intravenous infusion port (TIAP) is mainly used for patients who need central venous and poor peripheral vascular conditions. With the advantages of easy to carry, long maintenance cycle, few complications excellent quality life, it has been widely in fields malignant tumor chemotherapy, parenteral nutrition support repeated blood collection. (IVAP) dislocation can have significant if not recognised reinstated immediately.A 24-year-old man was treated with adjuvant chemotherapy...
Objective To study the mechanisms of extrarenal arterial blood supply renal malignancy for its interventional therapy.Methods Routine abdominal aortography and selective questionable feeding arteriography were performed in 141 patients with malignancy.The characteristics formation analyzed.Results Of patients,extrarenal found 51 there 87 branchs.The breakthrough capsule those patients.No extrarena]arterial was 90 patients,including 50 40 without emerge significantly different(x~2 =...