- Renal and Vascular Pathologies
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- MRI in cancer diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Advanced X-ray and CT Imaging
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Nonlinear Optical Materials Studies
- Peripheral Artery Disease Management
- Nonlinear Optical Materials Research
- Cardiovascular Health and Disease Prevention
- Cancer Mechanisms and Therapy
- Photonic and Optical Devices
- Mesenchymal stem cell research
- Tuberous Sclerosis Complex Research
- Angiogenesis and VEGF in Cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Medical Imaging and Pathology Studies
- Pediatric Urology and Nephrology Studies
- Intracranial Aneurysms: Treatment and Complications
- Photochemistry and Electron Transfer Studies
- Venous Thromboembolism Diagnosis and Management
- Fullerene Chemistry and Applications
- Endoplasmic Reticulum Stress and Disease
Peking University
2016-2025
Peking University First Hospital
2016-2025
First Affiliated Hospital of Chinese PLA General Hospital
2024
Fudan University
2024
Digital Health Cooperative Research Centre
2021
Creative Commons
2019
Texas Neurofibromatosis Foundation
2017
China National Nuclear Corporation
2012
Society of Interventional Radiology
2010
Peking University Shenzhen Hospital
2007
Crohn's disease (CD) and peripheral arterial (PAD) are closely related. The pathophysiological mechanisms underlying the coexistence of CD PAD unknown. aim this study was to investigate key molecules pathways mediating co-occurrence through quantitative bioinformatic analysis a public RNA sequencing database.Datasets (GSE111889) (GSE120642) were downloaded from Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) analyzed using 'edgeR' 'limma' packages R. Ontology...
Purpose: Portal vein tumor thrombus (PVTT)–related severe symptomatic portal hypertension (SPH) leads to a poor prognosis in patients with advanced hepatocellular carcinoma (HCC). Traditional transjugular intrahepatic portosystemic shunt (TIPS) using covered plus bare stent can effectively relieve SPH, however, the segment is susceptible obstruction due PVTT invasion. This study aimed evaluate safety and efficacy of fully stent-TIPS (FCS-TIPS) for treatment PVTT-related SPH HCC patients....
Objective Our study was to compare the therapeutic outcomes of radiofrequency ablation (RFA) with or without conventional transarterial chemoembolization (cTACE) for hepatocellular carcinoma (HCC) within Milan criteria in subcapsular versus nonsubcapsular locations by using propensity score matching.
Abstract Background Mesenchymal stem cells (MSCs) can improve limb perfusion and increase vessel density in a murine model of hindlimb ischemia. But low engraftment rate those limited their therapeutic effect. Endothelial (ECs) play an important role neovascularization. And MSCs differentiate into ECs vitro. The aim this study is to investigate if EC differentiation vitro before transplantation effective improving outcomes the treatment ischemic disease ischemia animal model. Methods were...
Objective To evaluate the long-term efficacy and safety of selective arterial embolization (SAE) in treatment renal angiomyolipomas (AMLs). Methods This was a retrospective review medical records imaging findings from patients with AMLs who attended our clinic received SAE between January 2007 2014. Only patents complete records, preoperative computed tomography scans using typical follow-up data were included. Results A total 79 enrolled study. Technical clinical success rates 100% 91% ( n...
Abstract In the pathological mechanism of pulmonary arterial hypertension, role apoptosis‐resistant microvascular endothelial cells (PVECs/AR) has been emphasized on vascular remodeling. present study, we investigated whether PVECs/AR can promote proliferation and migration smooth muscle (PASMCs), to study miR‐195‐5p in crosstalk between these two types cells. We confirmed that PASMCs a co‐culture system AR/PVECs PASMCs. Additionally, after exposure hypoxia for 12 or 24 h, had higher mature...
This study aimed to comprehensively evaluate non-contrast computed tomography (CT)-based radiomics for predicting early outcomes in patients with severe atherosclerotic renal artery stenosis (ARAS) after percutaneous transluminal angioplasty (PTRA). A total of 52 were retrospectively recruited, and their clinical characteristics pretreatment CT images collected. During a median follow-up period 3.7 mo, 18 confirmed have benefited from the treatment, defined as 20% improvement baseline...
Objective This study aimed to determine if superselective renal artery embolization is a safe and effective method of treating bleeding complications after percutaneous biopsy. Methods From January 2006 December 2017, 43 patients (22 men 21 women, mean age: 44.5 ± 14.0 years) underwent angiography for post-biopsy following Patients embolization. We recorded serum creatinine hemoglobin values assess the effect Results Successful was achieved in all patients. There pseudoaneurysm 10 cases,...
Early diagnosis of acute kidney injury (AKI) has clinical importance. Current methods are neither adequately sensitive nor specific. Blood oxygen level-dependent (BOLD) imaging and diffusion-weighted (DWI) may help to assess AKI in the early phase.To investigate feasibility BOLD DWI assessment compare sensitivities both techniques detection renal damage.Prospective animal study.Thirty New Zealand white rabbits.3 T MRI/BOLD DWI.Thirty rabbits were divided into three groups (severe group, mild...
Purpose The aim of this study was to explore a radiomics-clinical model for predicting the response initial superselective arterial embolization (SAE) in renal angiomyolipoma (RAML). Materials and methods A total 78 patients with RAML were retrospectively enrolled. Clinical data recorded evaluated. Radiomic features extracted from preoperative contrast-enhanced CT (CECT). Least absolute shrinkage selection operator (LASSO) intra- inter-class correlation coefficients (ICCs) used feature...
This study used contrast-enhanced ultrasound (CEUS) to evaluate changes in renal cortical blood perfusion after percutaneous transluminal angioplasty and stenting (PTRAS) for severe artery stenosis (RAS) (≥70%). CEUS was performed 21 patients with 24 RASs that underwent PTRAS. Renal quantitatively evaluated by comparing time intensity curve (TIC) parameters SonoVue (Bracco, Milan, Italy) contrast enhancement, including peak (PI), (TTP), mean transmit (MTT), ascending slope (S), area under...
The aim of this work was to develop long-term radiopaque microspheres (LRMs) by entrapping lipiodol in biocompatible polyvinyl alcohol with multiple emulsions chemical crosslinking method. high content (0.366 g/mL) hardly released from LRMs vitro and the radiopacity could maintain at least 3 months after subcutaneous injection mice without weakening. A series tests performed evaluate feasibility for embolization. were proved be smooth, spherical, well dispersed diameter range 100–1200 μm....
Objective This study was performed to determine whether transarterial chemoembolization (TACE) plus multi-imaging-guided radiofrequency ablation (MIG-RFA) can completely eliminate 3.1- 5.0-cm hepatocellular carcinoma (HCC) nodules and identify factors that may influence the complete elimination rate (CER) of this therapy. Methods Patients who underwent TACE+MIG-RFA for initial treatment HCC from January 2008 2016 were retrospectively reviewed. In total, 162 patients with 216 (3.1-5.0 cm)...
<b><i>Background:</i></b> Atherosclerotic renal artery stenosis (ARAS) is a condition where the arteries become narrowed due to atherosclerosis, leading reduced blood flow kidneys and various complications. The effectiveness of interventional treatments, such as angioplasty stenting, remains debated, making patient selection for these procedures challenging. <b><i>Summary:</i></b> This review focuses on diagnosis management ARAS, with...