Mengjie Fang

ORCID: 0000-0003-3027-3977
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced X-ray and CT Imaging
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • AI in cancer detection
  • Gastrointestinal Tumor Research and Treatment
  • Colorectal Cancer Screening and Detection
  • Medical Image Segmentation Techniques
  • Medical Imaging Techniques and Applications
  • Medical Imaging and Analysis
  • MRI in cancer diagnosis
  • Renal and Vascular Pathologies
  • Urinary and Genital Oncology Studies
  • Systemic Sclerosis and Related Diseases
  • Advanced Computing and Algorithms
  • Pancreatic and Hepatic Oncology Research
  • Cervical Cancer and HPV Research
  • Artificial Intelligence in Healthcare and Education
  • COVID-19 diagnosis using AI
  • Infrastructure Maintenance and Monitoring
  • Pelvic and Acetabular Injuries
  • Urological Disorders and Treatments
  • Flow Measurement and Analysis
  • Lung Cancer Treatments and Mutations
  • Non-Destructive Testing Techniques

Beihang University
2022-2025

Chinese Academy of Sciences
2019-2024

Institute of Automation
2024

First Affiliated Hospital of Wenzhou Medical University
2024

Hefei University of Technology
2024

Wenzhou Medical University
2024

Shandong Institute of Automation
2016-2023

Ministry of Industry and Information Technology
2022-2023

Shaoxing People's Hospital
2023

University of Chinese Academy of Sciences
2019-2022

The Coronavirus disease 2019 (COVID-19) is raging across the world. radiomics, which explores huge amounts of features from medical image for diagnosis, may help screen COVID-19. In this study, we aim to develop a radiomic signature COVID-19 CT images. We retrospectively collect 75 pneumonia patients Beijing Youan Hospital, including 46 with and 29 other types pneumonias. These are divided into training set (n = 50) test 25) at random. segment lung lesions images, extract 77 lesions. Then...

10.1007/s11432-020-2849-3 article EN other-oa Science China Information Sciences 2020-04-15

Abstract Federated learning (FL) has shown great potential in addressing data privacy issues medical image analysis. However, varying distributions across different sites can create challenges aggregating client models and achieving good global model performance. In this study, we propose a novel personalized contrastive representation FL framework, named PCRFed, which leverages to address the non-independent identically distributed (non-IID) challenge dynamically adjusts distance between...

10.1186/s42492-025-00191-0 article EN cc-by Visual Computing for Industry Biomedicine and Art 2025-03-28

Providing precise and comprehensive diagnostic information to clinicians is crucial for improving the treatment prognosis of nasopharyngeal carcinoma. Multi-modal foundation models, which can integrate data from various sources, have potential significantly enhance clinical assistance. However, several challenges remain: (1) lack large-scale visual-language datasets carcinoma; (2) inability existing pre-training fine-tuning methods capture hierarchical features required complex tasks; (3)...

10.1109/tmi.2025.3558775 article EN IEEE Transactions on Medical Imaging 2025-01-01

Objective: To develop and evaluate a diffusion-weighted imaging (DWI)-based radiomic nomogram for lymph node metastasis (LNM) prediction in advanced gastric cancer (AGC) patients. Overall Study: This retrospective study was conducted with 146 consecutively included pathologically confirmed AGC patients from two centers. All underwent preoperative 3.0 T magnetic resonance (MRI) examination. The dataset allocated to training cohort (n = 71) an internal validation 47) one center along external...

10.3389/fonc.2019.01265 article EN cc-by Frontiers in Oncology 2019-11-22

Encouraging and astonishing developments have recently been achieved in image-based diagnostic technology. Modern medical care imaging technology are becoming increasingly inseparable. However, the current diagnosis pattern of signal to image knowledge inevitably leads information distortion noise introduction procedure reconstruction (from image). Artificial intelligence (AI) technologies that can mine from vast amounts data offer opportunities disrupt established workflows. In this...

10.1016/j.eng.2023.02.013 article EN cc-by-nc-nd Engineering 2023-04-23

The potential prognostic value of extranodal soft tissue metastasis (ESTM) has been confirmed by increasing studies about gastric cancer (GC). However, the gold standard ESTM is determined pathologic examination after surgery, and there are no preoperative methods for assessment yet.

10.1002/mp.16647 article EN Medical Physics 2023-08-13

This study aimed to comprehensively evaluate non-contrast computed tomography (CT)-based radiomics for predicting early outcomes in patients with severe atherosclerotic renal artery stenosis (ARAS) after percutaneous transluminal angioplasty (PTRA). A total of 52 were retrospectively recruited, and their clinical characteristics pretreatment CT images collected. During a median follow-up period 3.7 mo, 18 confirmed have benefited from the treatment, defined as 20% improvement baseline...

10.1186/s42492-023-00152-5 article EN cc-by Visual Computing for Industry Biomedicine and Art 2024-01-12

Prognostic assessment remains a critical challenge in medical research, often limited by the lack of well-labeled data. In this work, we introduce ContraSurv, weakly-supervised learning framework based on contrastive learning, designed to enhance prognostic predictions 3D images. ContraSurv utilizes both self-supervised information inherent unlabeled data and cues present censored data, refining its capacity extract representations. For purpose, establish Vision Transformer architecture...

10.1109/jbhi.2024.3484991 article EN IEEE Journal of Biomedical and Health Informatics 2024-01-01

Abstract Background This study aimed to develope and validate a radiomics nomogram by integrating the quantitative characteristics of No.3 lymph nodes (LNs) primary tumors better predict preoperative node metastasis (LNM) in T1-2 gastric cancer (GC) patients. Methods A total 159 GC patients who had undergone surgery with lymphadenectomy between March 2012 November 2017 were retrospectively collected divided into training cohort (n = 80) testing 79). Radiomic features extracted from both...

10.1186/s12880-021-00587-3 article EN cc-by BMC Medical Imaging 2021-03-23

Gastric cancer is one of the most common malignancies, ranking fifth in incidence and third mortality worldwide.1Smyth E.C. Nilsson M. Grabsch H.I. et al.Gastric cancer.Lancet. 2020; 396: 635-648Summary Full Text PDF PubMed Scopus (686) Google Scholar The high rate mainly caused by delayed early diagnosis inappropriate choice treatment. Neoadjuvant chemotherapy (NACT) combined with surgery recommended as routine treatment options for locally advanced gastric (LAGC).2Xu Q. Sun Z. Li X....

10.1016/j.eclinm.2022.101380 article EN cc-by-nc-nd EClinicalMedicine 2022-04-01

Abstract Objective. In the realm of utilizing artificial intelligence (AI) for medical image analysis, paradigm ‘signal-image-knowledge’ has remained unchanged. However, process ‘signal to image’ inevitably introduces information distortion, ultimately leading irrecoverable biases in ‘image knowledge’ process. Our goal is skip reconstruction and build a diagnostic model directly from raw data (signal). Approach . This study focuses on computed tomography (CT) its (sinogram) as research...

10.1088/1361-6560/ad1e7c article EN cc-by Physics in Medicine and Biology 2024-01-15

Tumor localization and lymph node metastasis (LNM) diagnosis are two important tasks for gynecologist to make decisions in cervical cancer treatments. Aiming develop an accurate convenient system, we propose a multi-task residual cross-attention network named MRCNet tumor segmentation LNM prediction. Specifically, tackle task correlation with underlying related supervision information, capture multi-level features by multi-scale convolutional neural network, which equipped module concerning...

10.1109/isbi53787.2023.10230398 article EN 2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI) 2023-04-18

In this paper, we investigate the problem of predicting histopathological findings gastric cancer (GC) from preoperative CT image. Unlike most existing classification systems assess global imaging phenotype tissues directly, formulate as a generalized multi-instance learning (GMIL) task and design deep GMIL framework to address it. Specifically, proposed aims at training powerful convolutional neural network (CNN) which is able discriminate informative patches neighbor confusing yield...

10.1117/12.2512435 article EN Medical Imaging 2022: Image Processing 2019-03-14

<h3>Background:</h3> Systemic lupus erythematosus, characterized by a severe autoimmune disease with strong individual heterogeneity, is particularly important to study the risk factors that affect its prognosis in order determine patient outcome and treatment. Currently, numerous studies have proven EBV infection can onset of SLE. Nevertheless, due diverse clinical manifestations SLE complex status EBV, it difficult predict prognostic patients systemic erythematosus infection....

10.1136/annrheumdis-2024-eular.1072 article EN Annals of the Rheumatic Diseases 2024-06-01

10.1007/s13042-024-02438-3 article EN International Journal of Machine Learning and Cybernetics 2024-11-05

The construction of prognostic prediction models based on follow-up data is crucial for devising individualized treatment plans patients. However, the performance current supervised survival analysis methods constrained due to prevalence weakly censored samples during follow-up. To address this limitation, study introduces Prognostic Co-Training Regression (PCTR) algorithm, a semi-supervised model developed through co-training two KNN regressors. By integrating prior information data, PCTR...

10.1109/embc53108.2024.10782508 article EN 2024-07-15

Patient-targeted treatment of non-small cell lung carcinoma (NSCLC) has been well documented according to the histologic subtypes over past decade. In parallel, recent development quantitative image biomarkers recently highlighted as important diagnostic tools facilitate histological subtype classification. this study, we present a radiomics analysis that classifies adenocarcinoma (ADC) and squamous (SqCC). We extract 52-dimensional, CT-based features (7 statistical 45 texture features)...

10.1117/12.2253923 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2017-03-03

Abstract Recently, image-based diagnostic technology has made encouraging and astonishing development. Modern medical care imaging are increasingly inseparable. However, the current diagnosis pattern of Signal-to-Image-to-Knowledge inevitably leads to information distortion noise introduction in procedure image reconstruction (Signal-to-Image). Artificial intelligence (AI) technologies that can mine knowledge from vast amounts data offer opportunities disrupt established workflows. In this...

10.1101/2022.08.01.22278299 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-08-03

Accurately predict the risk of disease progression and benefit tyrosine kinase inhibitors (TKIs) therapy for stage IV non-small cell lung cancer (NSCLC) patients with activing epidermal growth factor receptor (EGFR) mutations by current staging methods are challenge. We postulated that integrating a classifier consisted multiple computed tomography (CT) phenotypic features, other clinicopathological factors into single model could improve stratification prediction progression-free survival...

10.1117/12.2253998 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2017-03-03

Objective evaluation of medical image segmentation is one the important steps for proving its validity and clinical applicability. Although there are many researches presenting methods on image, while with few studying their results, this paper presents a learning method combined measures to make it as close possible clinicians' judgment. This more quantitative precise diagnose. In our experiment, same data sets include 120 results lumen-intima boundary (LIB) media-adventitia (MAB) carotid...

10.1117/12.2214425 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2016-03-24
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