Jian Wang

ORCID: 0000-0002-7653-9577
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Sarcoma Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pelvic and Acetabular Injuries
  • Medical Imaging and Analysis
  • MRI in cancer diagnosis
  • Shoulder Injury and Treatment
  • Vascular Tumors and Angiosarcomas
  • Lung Cancer Treatments and Mutations
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Shoulder and Clavicle Injuries
  • Tuberous Sclerosis Complex Research
  • Liver Disease Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Bone Tumor Diagnosis and Treatments
  • State Capitalism and Financial Governance
  • Glioma Diagnosis and Treatment
  • Bone and Joint Diseases
  • Esophageal and GI Pathology
  • Renal and Vascular Pathologies
  • Infectious Diseases and Tuberculosis
  • Medical Imaging and Pathology Studies
  • Cervical and Thoracic Myelopathy

Peking University
2011-2024

Huashan Hospital
2024

Fudan University
2008-2024

Peking University First Hospital
2011-2024

Sichuan University
2024

West China Hospital of Sichuan University
2024

Pudong New Area People's Hospital
2024

Numerical Method (China)
2024

Weatherford College
2024

Qingzhou City People's Hospital
2024

Considerable research has been conducted concerning galectin-9 and carcinomas, but little information is available about any relation with the hepatocellular carcinoma. In this study, we employed a small interfering RNA (siRNA) targeting to down-regulate expression in HepG2 cells. As result, after was reduced, cell aggregation suppressed, while other behaviour such as proliferation, adhesion invasion ECM, cell-endothelial transendothelial of cells were markedly enhanced. When tumors 200...

10.7314/apjcp.2012.13.6.2503 article EN cc-by Asian Pacific Journal of Cancer Prevention 2012-06-30

Objective To evaluate the long-term efficacy and safety of selective arterial embolization (SAE) in treatment renal angiomyolipomas (AMLs). Methods This was a retrospective review medical records imaging findings from patients with AMLs who attended our clinic received SAE between January 2007 2014. Only patents complete records, preoperative computed tomography scans using typical follow-up data were included. Results A total 79 enrolled study. Technical clinical success rates 100% 91% ( n...

10.1177/0300060516684251 article EN cc-by-nc Journal of International Medical Research 2017-01-30

Background: The aim of this study was to compare the biomechanical performance pedicle screw construction and locking compression plate fixation in posterior pelvic ring injuries analyzed by finite element method. Methods: A 3-dimensional model spine-pelvis-femur complex with ligaments reconstructed from computed tomography images. An unstable injury created, which fixed a or plate. follower load 400 N applied upper surface vertebrae simulate body weight, while ends proximal femurs were...

10.1097/md.0000000000038258 article EN cc-by-nc Medicine 2024-05-17

Background: The pathogenic genes of colorectal cancer (CRC) have not yet been fully elucidated, and there is currently a lack effective therapeutic targets. This study used bioinformatics methods to explore experimentally validate the most valuable biomarkers for further investigate their potential as Methods: We analyzed differentially expressed (DEGs) based on Gene Expression Omnibus (GEO) dataset screened out hub genes. ROC curve univariate Cox analysis Cancer Genome Atlas (TCGA) revealed...

10.3389/fgene.2023.1265137 article EN cc-by Frontiers in Genetics 2023-09-29

Objective This study aimed to determine if superselective renal artery embolization is a safe and effective method of treating bleeding complications after percutaneous biopsy. Methods From January 2006 December 2017, 43 patients (22 men 21 women, mean age: 44.5 ± 14.0 years) underwent angiography for post-biopsy following Patients embolization. We recorded serum creatinine hemoglobin values assess the effect Results Successful was achieved in all patients. There pseudoaneurysm 10 cases,...

10.1177/0300060519828528 article EN cc-by-nc Journal of International Medical Research 2019-02-14

This is a prospective, consecutive series study to determine the role of Bryan artificial cervical disc replacement treat isolated herniation for Chinese patients.To evaluate intermediate clinical outcome and its limitations in management patients. Observing neurological improvement radiographic finding.Most people believe that anterior fusion factor shall not be ignored adjacent segment degeneration. Artificial replacement, as nonfusion technique, may offer solution this problem. The...

10.1097/bsd.0b013e3181e9f309 article EN Journal of Spinal Disorders & Techniques 2010-07-14

To prospectively compare single dose gadobenate dimeglumine with double gadopentetate for CE-MRA in patients peripheral arterial occlusive disease (PAOD) using an intra-individual crossover study design which all received both contrast agents otherwise identical examinations. Institutional review board and regulatory approval were granted provided written informed consent. Sixty-eight (53M/15F; 62.4 ± 15.7 years) mild-to-severe PAOD enrolled randomized 3-station 0.1 mmol/kg 0.2 dimeglumine....

10.1002/jmri.24040 article EN other-oa Journal of Magnetic Resonance Imaging 2013-01-31

Background Specific morphologic features of hepatocellular carcinoma (HCC) on imaging have identifiable pathologic correlates as well implications for altering surgical management and defining prognosis. In this study, we compared susceptibility-weighted (SWI) to conventional techniques correlated our findings with histopathology determine the role SWI in assessing HCC without using a contrast agent. Methods 86 consecutive patients suspected were imaged MRI (including T1, T2, T2*, SWI)...

10.1371/journal.pone.0098303 article EN cc-by PLoS ONE 2014-05-30

Purpose: To screen mitochondrial function-associated PCD-related biomarkers and construct a risk model for predicting the prognosis of early breast cancer. Methods: Data on gene expression levels clinical information were obtained from TCGA database, GSE42568 GSE58812 datasets GEO database. The programmed cell death (PCD) related genes in cancer identified, then LASSO logistic regression, SVM-RFE, random forest (RF), multiple Cox regression analysis employed to prognostic model. Differences...

10.3389/fgene.2024.1406426 article EN cc-by Frontiers in Genetics 2024-07-02

Background: Gastrectomy with D2 lymphadenectomy is a standard procedure of curative resection for gastric cancer (GC). The aim this study was to develop simple and reliable prognostic scoring system GC treated gastrectomy combined adjuvant chemotherapy. Methods: A established based on clinical laboratory data from 579 patients localized without distant metastasis Results: From the multivariate model overall survival (OS), five factors were selected system: ≥50% metastatic lymph node rate,...

10.2147/dddt.s88743 article EN cc-by-nc Drug Design Development and Therapy 2016-02-01

This retrospective study aims to evaluate the effect of prolonged methylprednisolone (MP) therapy on mortality patients with moderate-to-severe paraquat (PQ) poisoning after pulse treatment. We performed a analysis acute PQ that were admitted emergency department from May 2012 August 2016. Out 138 patients, 60 treated treatment (15 mg kg–1 day–1 MP for 3 days) and 78 days; afterward, dosage was reduced in half every 2 days, terminated until 0.47 day–1). Kaplan–Meier method used compare...

10.1097/md.0000000000007244 article EN cc-by-nc Medicine 2017-06-01

Objective This study was performed to determine whether transarterial chemoembolization (TACE) plus multi-imaging-guided radiofrequency ablation (MIG-RFA) can completely eliminate 3.1- 5.0-cm hepatocellular carcinoma (HCC) nodules and identify factors that may influence the complete elimination rate (CER) of this therapy. Methods Patients who underwent TACE+MIG-RFA for initial treatment HCC from January 2008 2016 were retrospectively reviewed. In total, 162 patients with 216 (3.1-5.0 cm)...

10.1177/0300060518768420 article EN cc-by-nc Journal of International Medical Research 2018-04-23

Despite advances in care, the 5 year overall survival for patients with relapsed and or metastatic sarcoma remains as low < 35%. Currently, there are no biomarkers available to assess disease status sarcomas such, surveillance reliant on serial imaging which increases risk of secondary malignancies heightens patient anxiety.Here, first time reported literature, we have enumerated cell surface vimentin (CSV+) CTCs blood 92 pediatric adolescent young adult (AYA) a possible marker disease.We...

10.3389/fonc.2021.760267 article EN cc-by Frontiers in Oncology 2021-12-09

// Qun-Ying Yang 1, * , Cheng-Cheng Guo Mei-Ling Deng 2 Jian Wang 1 Jing Fu-hua Lin Ji Zhang Xiao-Bing Jiang Yong-Gao Mou Zhong-Ping Chen State Key Laboratory of Oncology in South China, Department Neurosurgery/Neuro-Oncology at The Cancer Center Sun Yat-sen University, Collaborative Innovation Oncology, Guangzhou 510060, China Radiotherapy These authors have contributed equally to this work Correspondence to: Chen, email: chenzhp@sysucc.org.cn Keywords: primary intracranial germ cell tumor,...

10.18632/oncotarget.10218 article EN Oncotarget 2016-06-22

Albeit rare, rhabdomyosarcoma (RMS) may occur in middle to old-aged adults. The purpose of this study was investigate the clinicopathological characteristics and prognosis RMS patients ≥ 40 years age.The clinical, pathological immunohistochemical profiles 76 cases were reviewed, outcomes analyzed.There 46 males 30 females with a median age 55 years. Sixty occurred somatic soft tissues, including extremities (n = 25), head neck 19) trunk 16). Sixteen developed internal organs predilection for...

10.3760/cma.j.issn.0253-3766.2012.12.007 article EN PubMed 2012-12-01
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