Purpose To assess the accuracy of magnetic resonance (MR) imaging-based differential diagnosis hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) in a cohort patients with focal liver lesions cirrhosis. Materials Methods This study was institutional review board approved, requirement for informed consent waived. Between January 2009 December 2014, cirrhotic patients, including 71 ICC 612 HCC, underwent unenhanced T1- T2-weighted MR imaging, gadolinium-based contrast...

18F-FDG PET/CT could satisfactorily show pancreatic and extra-pancreatic lesions in AIP, which can be mistaken for cancer (PC). This study aimed to identify findings that might differentiate AIP from PC.FDG-PET/CT of 26 40 PC patients were reviewed. Pancreatic related findings, including maximum standardized uptake values (SUVmax) patterns FDG uptake, identified compared.All with had increased uptake. Focal abnormal activities found 38/40 (95.00%) patients, while longitudinal 18/26 (69.23%)...

Both portal vein embolization (PVE) and associating liver partition ligation for staged hepatectomy (ALPPS) have merits demerits when used in patients with unresectable cancers due to insufficient volumes future remnant (FLR).This study was a single-center, prospective randomized comparative study. Patients the diagnosis of hepatitis B related hepatocellular carcinoma (HCC) were randomly assigned 1:1 ratio 2 groups. The primary endpoints tumor resection three-year overall survival (OS)...

Phototherapy is a powerful, noninvasive approach for cancer treatment, with several agents currently in clinical use. Despite the progress and promise, most current phototherapy have serious side effects as they can lead to damage healthy tissue, even when photosensitizers are fused targeting molecules due nonspecific light activation of unbound photosensitizer. To overcome these limitations, we developed agent that combines functional ligand near infrared phthalocyanine dye. Our target type...

Portal vein tumor thrombosis (PVTT) in hepatocellular carcinoma (HCC) is a sign of advanced stage disease, which associated with poor prognosis. Liver resection (LR) may provide better prognosis selected patients. In the present study, we aimed to assess information from HCC patients PVTT who died within 3 months or 2 years after LR order identify preoperative factors correlated short-term long-term survival, by inappropriate selection for might be avoided future.

The study aimed to explore the value of CT findings and inflammatory indicators in differentiating benign malignant gallbladder polypoid lesions before surgery.The comprised a total 113 pathologically confirmed with maximum diameter ≥ 1 cm (68 45 malignant), all which were enhanced CT-scanned within month surgery. patients analyzed by univariate multivariate logistic regression analysis identify independent predictors lesions, then nomogram distinguishing was developed combining these...

The low-dose computed tomography (CT) technique has been widely used because it decreases the potential risk of radiation exposure, as well enabling CT-guided lung lesion biopsy. However, uncertainties remain regarding diagnostic accuracy, dose, complication rate, and image quality.To compare quality biopsy between conventional techniques.A total 90 patients were prospectively enrolled randomized into two groups (group A: 120 kv; 200 mA; thickness, 2.0 mm; pitch, 16 mm/rot; n = 44; group B:...

Cryptococcosis with thoracic spine involvement is extremely rare, most cases occurring in immunosuppressed patients. We report a case of cryptococcosis the vertebrae confirmed by histopathology. The immunocompetence patient interesting feature this case. Laboratory investigations were normal, but erythrocyte sedimentation rate was raised. A computed tomography scan showed an eccentric lytic lesion clear boundary at T2-T3. Magnetic resonance imaging endplates T2 and T3 vertebral bodies to be...

The success of targeted cancer therapy largely relies upon the selection target and development efficient therapeutic agents that specifically bind to target. In current study, we chose a cannabinoid CB2 receptor (CB2R) as new used CB2R-targeted photosensitizer, IR700DX-mbc94, for phototherapy treatment. IR700DX-mbc94 was prepared by conjugating IR700DX, mbc94, whose binding specificity CB2R has been previously demonstrated. We found treatment using greatly inhibited growth positive tumors...

This paper aimed to evaluate the effect of preoperative transarterial embolization (TAE) on estimated blood loss (EBL) during surgical excision vertebral tumors. Three hundred and forty-eight patients with spinal tumors were retrospectively analyzed. The TAE group consisted 190 control 158 patients. Gelatin sponge particles mixed withy contrast agent used in embolize tumor-feeding artery. factors evaluated included: time interval between embolism surgery; number vertebrae involved by tumor;...

Triple-negative breast cancer (TNBC) is a devastating disease worldwide, for which targeted imaging and therapeutic agents remain elusive. There has been growing awareness that carbohydrates are valuable as drug candidates targeting variety of human diseases, including cancers overexpress carbohydrate receptors on the cell surface. Here, we develop two-dimensional (2D) glycocluster by means simple, stepwise self-assembly delivery theranostic to TNBC cells express mannose (MRs) Human serum...

To investigate the clinical features of undifferentiated embryonal sarcoma liver (UESL) to improve its preoperative diagnostic accuracy.The clinical, imaging, and histopathologic findings 16 UESL patients whose disease was pathologically confirmed but preoperatively misdiagnosed were retrospectively analyzed.Among these patients, 9 clinically as primary cancer, 3 hepatoblastoma, 4 malignant hepatic mass. In 12 who presented due abdominal discomfort, ultrasound showed that predominantly solid...

Background. The distinction between combined hepatocellular-cholangiocarcinoma (cHCC-CC) and hepatocellular carcinoma (HCC) before the operation has an important clinical significance for optimizing treatment plan predicting prognosis of patients. Magnetic resonance imaging (MRI) been widely used in preoperative diagnosis evaluation primary liver malignant tumors. Purpose. aim is to study value data enhanced MRI differential HCC cHCC-CC obtain independent risk factors cHCC-CC. Study type....

The present study aimed to develop and validate a preoperative model based on gadobenate-enhanced magnetic resonance imaging (MRI) for predicting microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) size of ≤5 cm. In order provide guidance clinicians optimize treatment options.164 pathologically confirmed HCC MRI from July 2016 December 2020 were retrospectively included. Univariate multivariate logistic regression (forward LR) analyses used determine the predictors...

Microvascular invasion (MVI) is significantly associated with prognosis in combined hepatocellular-cholangiocarcinoma (cHCC-CCA) patients. The study aimed to explore the value of preoperative contrast-enhanced CT (CECT) features and clinical data predicting MVI cHCC-CCA.A total 33 patients MVI-positive 27 MVI-negative were enrolled, underwent CECT imaging from January 2016 December 2021. Preoperative retrospectively analyzed. Univariable multivariable logistic regression analysis performed...

Lipopolysaccharide binding protein (LBP) has been reported to be associated with prognosis in colorectal carcinoma and renal cell carcinoma; however, the clinical significance of LBP human primary hepatocellular (HCC) is inconclusive. We aimed investigate prognostic value HCC. In present study, 346 patients HCC who underwent curative resection were retrospectively analyzed. expression was evaluated using western blot analysis immunohistochemistry. scores collected from immunohistochemical...