Alessandro Silvestri

ORCID: 0000-0002-3367-5819
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About
Contact & Profiles
Research Areas
  • Medical and Biological Sciences
  • Risk and Safety Analysis
  • Reliability and Maintenance Optimization
  • Electrochemical sensors and biosensors
  • Scheduling and Optimization Algorithms
  • dental development and anomalies
  • Quality and Supply Management
  • Carbon and Quantum Dots Applications
  • Assembly Line Balancing Optimization
  • Multi-Criteria Decision Making
  • Graphene research and applications
  • Nanocluster Synthesis and Applications
  • Occupational Health and Safety Research
  • 2D Materials and Applications
  • Advanced biosensing and bioanalysis techniques
  • Advanced Manufacturing and Logistics Optimization
  • Graphene and Nanomaterials Applications
  • Reconstructive Surgery and Microvascular Techniques
  • Facial Trauma and Fracture Management
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Nanoparticle-Based Drug Delivery
  • Quality and Safety in Healthcare
  • Craniofacial Disorders and Treatments
  • Manufacturing Process and Optimization
  • Quality and Management Systems

Ca' Foscari University of Venice
2023-2025

CIC biomaGUNE
2020-2024

Università degli studi di Cassino e del Lazio Meridionale
2014-2024

Ayuntamiento de San Sebastián
2021

Boeing (Spain)
2021

Digital Research Alliance of Canada
2021

Max Planck Institute of Colloids and Interfaces
2017-2020

Max Planck Institute of Molecular Plant Physiology
2020

Curtin University
2019-2020

Institute of Molecular Science and Technologies
2014-2018

The detection of cancer biomarkers at an early stage tumor development is vital for effective diagnosis and treatment cancer. Current diagnostic tools can often detect only when the biomarker levels are already too high, so that tumors have spread treatments less effective. It urgent therefore to develop highly sensitive assays such lowest possible concentration. In this context, we developed a sandwich immunoassay based on surface-enhanced Raman scattering (SERS) ultrasensitive...

10.1021/acsami.0c22203 article EN cc-by-nc-nd ACS Applied Materials & Interfaces 2021-02-13

Abstract The drive to lower operating costs and improve manufacturing efficiency has led many companies implement different methodologies in order identify a suitable risk assessment model. So, the concern for safety industrial activities, both inside establishments their surroundings, crucial role. As result, laws, regulations analysis techniques are well adapted industry needs since they were developed its purpose. However increasing is often difficult, especially when you have already...

10.1080/00207543.2012.657968 article EN International Journal of Production Research 2012-04-24

The risk-based approach is one of the keys used in implementation management systems using requirements from standards. If are implemented separately, risks evaluated only perspective, but when two or more integrated, must take into account synergetic effects due to system integration. paper aims highlight specific encountered implementing organizations, underlining associated with and integrated systems. In this work, a synthesis was presented including an analysis that occurred during...

10.3390/su151310251 article EN Sustainability 2023-06-28

Serotonin concentration in peripherical biological fluids is correlated with the insurgence of several pathologies and represents valuable information on human physical mental state health. Rapid, portable, reliable electrochemical sensors can mine this useful real-time situ. However, main challenge that hampers their implementation poor operational stability rich bio-macromolecules, which induce fouling electrode altering or invalidating analytical performance sensor. Herein, we propose...

10.1016/j.carbon.2024.119550 article EN cc-by Carbon 2024-08-15

Safety is one of the most important issues in modern industrial plants and activities. The Engineering role to ensure acceptable safety levels production systems, not only respect local laws regulations, but also improve efficiency reduce manufacturing costs. For these reasons, choice a proper model for risk assessment crucial. In this context, present research aims propose new method, called Total Efficient Risk Priority Number (TERPN), able classify risks identify corrective actions order...

10.1080/13669877.2017.1307260 article EN Journal of Risk Research 2017-04-10

In this paper the first example of using C-dots (CDs) as sensing nanomaterial for monitoring low concentrations NO2 in ambient air is reported. logic to support a green circular economy, CDs were prepared from natural cost precursor consisting olive solid waste (OSW) by simple pyrolysis process combined with chemical oxidation. Characterization data showed formation spherical dimensions narrow size range 0.5 5 nm and charged functional groups (COO- (carboxylate), C-O-C (epoxide) C-OH...

10.1016/j.cartre.2021.100105 article EN cc-by-nc-nd Carbon Trends 2021-09-06

Abstract Hundreds of new electrochemical sensors are reported in literature every year. However, only a few them makes it to the market. Manufacturability, or rather lack it, is parameter that dictates if sensing technologies will remain forever laboratory which they conceived. Inkjet printing low‐cost and versatile technique can facilitate transfer nanomaterial‐based Herein, an electroactive self‐assembling inkjet‐printable ink based on protein‐nanomaterial composites exfoliated graphene...

10.1002/smll.202300163 article EN cc-by-nc Small 2023-05-05

The electrostatic functionalization between negative-charged 1T-MoS 2 and positive-charged alkylammonium salts allows high yields while preserving the material's favorable properties.

10.1039/d4nr05515b article EN cc-by-nc Nanoscale 2025-01-01

The development of new molecules able to efficiently act as long‐circulating computed tomography (CT) contrast agents is one the most crucial topics in biomedical field. In last years, chance manipulate materials at nano‐size level gave boost this research, with specific aim design innovative nanoprobes. Gold nanoparticles (AuNPs) have showed unique X‐rays attenuation properties which, combined their easy surface functionalization, makes them ideal candidates for next generation agents....

10.1002/cmmi.1704 article EN Contrast Media & Molecular Imaging 2016-07-04

Abstract The choice of a reliability allocation method is not always easy or straightforward, since it depends on several factors. Some factors are directly related to the characteristics analyzed system, such as level complexity configuration; other hand, additional aspects constitute boundary conditions, budget experimentation time. In this scenario, purpose present research systematic literature review allocation, proposing guideline choose optimal in respect desired application,...

10.1002/qre.2675 article EN Quality and Reliability Engineering International 2020-07-07

Purpose The paper aims to evaluate reliability allocation using an aerospace system prototype. proposed approach has been applied and compared with other traditional methods on prototype, where the process is rigorous. Design/methodology/approach new based Integrated factors Method (IFM), whose values are adjusted trough a multicriteria method, Analytic Hierarchy Process, depending importance of each factor unit system. result dynamic model, that combines advantages method decision-making...

10.1108/ijqrm-05-2015-0082 article EN International Journal of Quality & Reliability Management 2016-03-10

Abstract With the advent of flexible electronics, old fashioned and conventional solid‐state technology will be replaced by conductive inks combined with low‐cost printing techniques. Graphene is an ideal candidate to produce inks, due its excellent conductivity zero bandgap. The possibility chemically modify graphene active molecules opens up field responsive inks. Herein, a bioresponsive, electroactive, inkjet‐printable ink presented. based on modified selected enzymes electrochemical...

10.1002/adfm.202105028 article EN cc-by Advanced Functional Materials 2021-10-05

COVID-19, caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), originated a global health crisis, causing over million casualties and altering human daily life all world. This pandemic emergency revealed limitations of current diagnostic tests, highlighting urgency to develop faster, more precise sensitive sensors. Graphene field effect transistors (GFET) are analytical platforms that enclose these requirements. However, design robust GFET is not straightforward...

10.1039/d2nr05103f article EN Nanoscale 2022-12-16

Recently, fluorescent sensors have gained considerable attention due to their high sensitivity, low cost and noninvasiveness. Among the different materials that can be used for this purpose, carbon dots (CDs) represent valuable candidates applications in sensing. These, indeed, are easily synthesized, show quantum yield highly biocompatible. However, it was pointed out photoluminescence properties of these nanomaterials strictly dependent on synthetic purification methods adopted. The...

10.3390/ijms25105370 article EN International Journal of Molecular Sciences 2024-05-14

To prospectively evaluate the short and long term clinical impact of selective transarterial chemoembolization (TACE) on liver function in patients with hepatocellular carcinoma (HCC). assess side effects relation to treatments. analyze overall survival HCC progression free probability.One hundred seventeen cirrhotic were enrolled. Baseline included Child-Pugh score serum levels alanine-aminotransferase (ALT), prothrombin time (PT) bilirubin. According Cancer Liver Italian Program (CLIP)...

10.3748/wjg.15.1843 article EN cc-by-nc World Journal of Gastroenterology 2009-01-01

Fluorescence correlation spectroscopy allows the of state aggregation <italic>in vitro</italic> with intracellular fate gold NPs for different antifouling coatings.

10.1039/c7nr04640e article EN Nanoscale 2017-01-01
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