- 2D Materials and Applications
- Graphene research and applications
- Semiconductor materials and devices
- Gas Sensing Nanomaterials and Sensors
- Physics of Superconductivity and Magnetism
- RNA Research and Splicing
- Wnt/β-catenin signaling in development and cancer
- Nanowire Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Ubiquitin and proteasome pathways
- Superconducting Materials and Applications
- GaN-based semiconductor devices and materials
- Semiconductor Quantum Structures and Devices
- Transition Metal Oxide Nanomaterials
- Metal and Thin Film Mechanics
- Carbon Nanotubes in Composites
- Polyamine Metabolism and Applications
- Acoustic Wave Resonator Technologies
- Thin-Film Transistor Technologies
- Advancements in Semiconductor Devices and Circuit Design
- Ferroelectric and Piezoelectric Materials
- Kruppel-like factors research
- Superconductivity in MgB2 and Alloys
- CCD and CMOS Imaging Sensors
- Microwave Dielectric Ceramics Synthesis
Korea Institute of Materials Science
2009-2019
Government of the Republic of Korea
2018-2019
Changwon National University
2018-2019
Yeungnam University
1999-2018
Hanyang University
2018
Chung-Ang University
2012
Osaka City University
2003-2010
Korea Electronics Technology Institute
2009
Ceracomp (South Korea)
2007-2008
Korea Atomic Energy Research Institute
2003
Two-dimensional (2D) molybdenum disulphide (MoS2) atomic layers have a strong potential to be used as 2D electronic sensor components. However, intrinsic synthesis challenges made this task difficult. In addition, the detection mechanisms for gas molecules are not fully understood. Here, we report high-performance constructed using atomic-layered MoS2 synthesised by chemical vapour deposition (CVD). A highly sensitive and selective based on CVD-synthesised was developed. situ...
We report the production of a two-dimensional (2D) heterostructured gas sensor. The gas-sensing characteristics exfoliated molybdenum disulfide (MoS2) connected to interdigitated metal electrodes were investigated. MoS2 flake-based sensor detected NO2 concentration as low 1.2 ppm and exhibited excellent stability. Instead electrodes, patterned graphene was used for charge collection in MoS2-based sensing devices. An equation based on variable resistance terms describe mechanism graphene/MoS2...
A Wnt coreceptor low-density lipoprotein receptor-related protein 5 (LRP5) plays an essential role in bone accrual and eye development. Here, we show that LRP5 is also required for normal cholesterol glucose metabolism. The production of mice lacking revealed deficiency led to increased plasma levels fed a high-fat diet, because the decreased hepatic clearance chylomicron remnants. In addition, when LRP5-deficient showed markedly impaired tolerance. islets had marked reduction intracellular...
Two-dimensional (2D) molybdenum disulfide (MoS2) atomic layers have a strong potential to be adopted for 2D electronic components due extraordinary and novel properties not available in their bulk foams. Unique of the MoS2, including quasi-2D crystallinity, ultrahigh surface-to-volume, high absorption coefficient, enabled high-performance sensor applications. However, implementation only single-functional presents limitation various advanced multifunctional applications within single device....
The effect of MnO(2) addition on the dielectric and piezoelectric properties 0.4Pb(Mg(13)Nb(23))O(3)-0.25PbZrO(3)-0.35PbTiO(3) single crystals was investigated. Analogous to acceptor doping in "hard" Pb(Zr,Ti)O(3) based polycrystalline materials, Mn doped exhibited enhanced mechanical Q ( approximately 1050) with low loss 0.2%), while maintaining ultrahigh electromechanical coupling k(33)>90%, inherent domain engineered crystals. also evident build-up an internal bias (E(i) 1.6 kVcm), shown...
We first report that two-dimensional (2D) metal (NbSe2)-semiconductor (WSe2)-based flexible, wearable, and launderable gas sensors can be prepared through simple one-step chemical vapor deposition of prepatterned WO3 Nb2O5. Compared to a control device with Au/WSe2 junction, gas-sensing performance the 2D NbSe2/WSe2 was significantly enhanced, which might have resulted from formation NbxW1-xSe2 transition alloy junction lowering Schottky barrier height. This would make it easier collect...
LDL receptor-related protein 5 (LRP5) plays multiple roles, including embryonic development and bone accrual development. Recently, we demonstrated that LRP5 is also required for normal cholesterol metabolism glucose-induced insulin secretion. To further define the role of in lipoprotein metabolism, compared plasma lipoproteins mice lacking LRP5, apolipoprotein E (apoE), or both (apoE;LRP5 double knockout). On a chow diet, apoE;LRP5 knockout (older than 4 months age) had ∼60% higher levels...
We fabricated p-i-n diodes by sputtering alternating layers of silicon dioxide and rich oxide with a nominal atomic ratio O/Si=0.7 onto quartz substrates in situ boron for p-type phosphorus n-type doping. After crystallization, dark illuminated I-V characteristics show diode behavior an open circuit voltage 373 mV. Due to the thinness their corresponding high resistivity, lateral current flow results severe crowding. This effect is taken into account when extracting electronic bandgap based...
Heterostructures of compositionally and electronically variant two-dimensional (2D) atomic layers are viable building blocks for ultrathin optoelectronic devices. We show that the composition interfacial transition region between semiconducting WSe2 layer channels metallic NbSe2 contact can be engineered through doping with Nb atoms. WxNb1-xSe2 regions considerably lower potential barrier height junction, significantly improving performance corresponding WSe2-based field-effect transistor...
The long-term stability and superior device reliability through the use of delicately designed metal contacts with two-dimensional (2D) atomic-scale semiconductors are considered one critical issues related to practical 2D-based electronic components. Here, we investigate origin improved contact properties alloyed 2D metal–semiconductor heterojunctions. WSe2-based transistors mixed transition layers containing van der Waals (M–vdW, NbSe2/WxNb1–xSe2/WSe2) junctions realize atomically sharp...
By expression cloning using fluorescent-labeled high density lipoprotein (HDL), we isolated two clones that conferred the cell surface binding of HDL. Nucleotide sequence revealed one corresponds to scavenger receptor class B, type 1 (SRBI) and other encoded a novel protein with 228 amino acids. The primary structure newly identified HDL-binding resembles GPI-anchored proteins consisting an N-terminal signal sequence, acidic region cluster aspartate glutamate residues, Ly-6 motif highly...
We have investigated the effects of metal decoration on gas-sensing properties a device with two-dimensional (2D) molybdenum disulfide (MoS₂) flake channels and graphene electrodes. The 2D hybrid-structure sensitively detected NO₂ gas molecules (>1.2 ppm) as well NH₃ (>10 ppm). Metal nanoparticles (NPs) could tune electronic graphene/MoS₂ device, increasing sensitivity to specific molecule. For instance, palladium NPs accumulate hole carriers graphene/MoS₂, electronically sensitizing...
Apolipoprotein E receptor 2 is a recently identified that resembles low and very density lipoprotein receptors. Isolation characterization of genomic clones encoding human apolipoprotein revealed the gene spans ~60 kilobases contains 19 exons. The positions exon/intron boundaries are almost identical to those Fluorescent in situ hybridization chromosomes located on chromosome 1p34. cDNA variant reverse transcription-polymerase chain reaction indicate presence multiple variants with different...
Pb ( Mg 1 ∕ 3 Nb 2 ) O – Zr Ti (PMN-PZT) ferroelectric single crystals were grown successfully using the solid state crystal growth method. The found to exhibit higher Curie temperatures TCs and phase transition TR-Ts when compared binary Pb(Mg1∕3Nb2∕3)O3–PbTiO3 system. Specifically composition 0.4Pb(Mg1∕3Nb2∕3)O3–0.25PbZrO3–0.35PbTiO3 which lies close rhombohedral-tetragonal morphotropic boundary, was investigated. full set of materials constants, including elastic (c s), piezoelectric (d,...
Rohit Chikkaraddy opened the discussion of Introductory Lecture: Regarding quantifying chemical enhancement, you showed a systematic change in SERS enhancement for halide substituted molecules due to charge transfer from metal. Is extra an inherent increas
A sponge-based surface-enhanced Raman scattering (SERS) sensor composed of silver nanowires (AgNWs) coated with hydrophobic hexagonal boron nitride (hBN) was prepared for the simultaneous separation and detection organic pollutants.
We identified seven novel polymorphisms in the human low density lipoprotein receptor related protein 5 (LRP5) gene. Two of them are predicted to replace amino acid LRP5 (c.314A>G: Q89R and c.4037T>C: V1330A), whereas three silent mutations coding region (c.2268T>C: N740N, c.3405A>G: V1119V, c.4137C>T: D1363D) two introns (IVS10+6T>C IVS17-30G>A). Since recognizes apolipoprotein E is genetically linked with type 1 diabetes, these will be useful genetic studies hyperlipoproteinemia diabetes....
The Prp2 protein of Saccharomyces cerevisiae is an RNA-dependent ATPase required before the first transesterification reaction in pre-mRNA splicing. binds to spliceosome absence ATP and released following hydrolysis. We determined what regions are essential for release from by analyzing dominant negative mutants vivo vitro. made mutations conserved motif II (DExH) VI (QRxGR) helicase (H) domain. Mutations that inactivated PRP2 had a phenotype when overexpressed vivo. To test whether outside...
There has been growing research interest in realizing optoelectronic devices based on the two-dimensional atomically thin semiconductor MoS2 owing to its distinct physical properties that set it apart from conventional semiconductors. However, there is little optical absorption these extremely layers, which presents an obstacle toward applying them for use high-efficiency light-absorbing devices. We synthesized trilayers of directly SiO2/Si nanocone (NC) arrays using chemical vapor...
The aim of this study was to assess the expression DKK3 protein and its target, beta-catenin, in uterine cervical squamous cell carcinoma determine potential clinical correlations.Six in-situ (CIS) tissues 88 invasive cancer were included study. Twenty-two normal one gastric tissue used as controls. beta-catenin proteins evaluated by immunohistochemical analysis. Clinical pathological parameters obtained from medical records. Survival data estimated using Kaplan-Meier estimates compared with...
In this work we report the direct nano-bridging of carbon nanotubes (CNT) between micro-sized islands using conventional photolithography technique necessary for nanomachining and molecular device applications compatible with Si-based process. The most distinct feature in is to use a growth barrier Nb metal or insulating layer on top catalytic prevent CNT from vertical direction substrate. As result, CNTs either “straight line” perfect “Y shape” were selectively grown lateral sides metals...
Developing a sensor that identifies and quantifies trace amounts of analyte molecules is crucially important for widespread applications, especially in the areas chemical biological detection. By non-invasively identifying vibrational signatures target molecules, surface-enhanced Raman scattering (SERS) has been widely employed as tool molecular Here, we report on reproducible fabrication wafer-scale dense SERS arrays single-nanogap level near-field imaging these under ambient conditions....