A5003277400- Bone Tissue Engineering Materials
- Engineering Technology and Methodologies
- Surface Treatment and Coatings
- Advanced materials and composites
- Polymer Surface Interaction Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Calcium Carbonate Crystallization and Inhibition
- Hydrogels: synthesis, properties, applications
- 3D Printing in Biomedical Research
- Graphene and Nanomaterials Applications
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticles: synthesis and applications
- Advanced biosensing and bioanalysis techniques
- Advanced Sensor and Energy Harvesting Materials
- Spectroscopy Techniques in Biomedical and Chemical Research
- Nuclear Physics and Applications
- Advanced Fiber Optic Sensors
- Photonic and Optical Devices
- Photonic Crystal and Fiber Optics
- Quantum Dots Synthesis And Properties
- Material Properties and Applications
- Gyrotron and Vacuum Electronics Research
- Advancements in Transdermal Drug Delivery
- Coal and Coke Industries Research
Saratov State University
2013-2021
Saratov Research Center
2016-2018
Yuri Gagarin State Technical University of Saratov
2016
Institute for Physics of Microstructures
2016
International Society for Optics and Photonics
2015
Abstract We demonstrate a novel approach to the controlled loading of inorganic nanoparticles and proteins into submicron- micron-sized porous particles. The is based on freezing/thawing cycles, which lead high densities. process was tested for inclusion Au, magnetite nanoparticles, bovine serum albumin in biocompatible vaterite carriers micron submicron sizes. amounts loaded or substances were adjusted by number cycles. Our method afforded at least three times higher four protein particles,...
We have designed multifunctional silver alginate hydrogel microcontainers referred to as loaded microcapsules with different sizes by assembling them via a template assisted approach using natural, highly porous calcium carbonate cores. Sodium was immobilized into the pores of particles followed cross-linking addition ions, which had dual purpose: on one hand, were used agent, albeit in monovalent form, while other hand they led formation nanoparticles. Monovalent an unusual improve...
The state of the art in optical biosensing is focused on reaching high sensitivity at a single wavelength by using any type resonance. This common strategy, however, disregards promising possibility simultaneous measurements bioanalyte's refractive index over broadband spectral domain. Here, we address this issue introducing approach in-fibre multispectral sensing (IMOS). operating principle relies detecting changes transmission hollow-core microstructured fibre when bioanalyte streamed...
Composite bioceramic and hydrogel-based containers harboring alkaline phosphatase are generated through encapsulation of this enzyme by its immobilization into CaCO3-based materials in combination with a hydrogel assembly technique subsequent gelification. A refined way synthesis modification allows preparing the delivery system functionalized protection layers. The particles characterized electron microscopy, Fourier transform infrared (FTIR) spectroscopy, activity measurements. Loading...
Abstract Novel bone growth‐stimulating interfaces are designed via surface modification of titanium (Ti) surfaces using the bioceramic CaCO 3 in vaterite phase, Ca‐crosslinked alginate hydrogel, or a blend these two materials with an active enzyme, alkaline phosphatase (ALP), as osteoinductive component. The morphology and chemistry engineered investigated scanning electron microscopy, atomic force Fourier transform infrared spectroscopy, while crystal fraction within inorganic phase...
At present day, silver nanoparticles are widely used in different fields of human activity. Due to the unique combination physical and chemical properties, have high reactivity antibacterial activity against microorganisms. For same reason, can render a cytotoxic effect on eukaryotic cells. The usage polymeric compounds as stabilizers allow reducing it saving With this regard, examination new nanoparticles' is vital task. In addition, for safe necessary estimate some their properties...
Multifunctional silver alginate hydrogel microspheres are assembled <italic>via</italic> a template assisted approach using calcium carbonate cores.
Abstract Efficient delivery of genetic material to primary cells remains challenging. Here, efficient transfer is presented using synthetic biodegradable nanocarriers, resembling extracellular vesicles in their biomechanical properties. This based on two main technological achievements: generation soft polyelectrolyte capsules nanosize and application the nanocapsules for co‐transfer different RNAs tumor cell lines cells, including hematopoietic progenitor T cells. Near 100% efficiency...
Magnetic contrast agents are widely used in magnetic resonance imaging order to significantly change the signals from regions of interest comparison with surrounding tissue. Despite a high variety single-mode T1 or T2 agents, there is need for dual-mode one agent. Here, we report on synthesis submicron carriers, containing Fe3O4 nanoparticles their structure. We show ability control by changing not only number magnetite carrier concentration suspension but also structure core–shell itself....
The photocatalytic degradation of organic molecules is one the effective ways for water purification. At this point, microreactor systems seem to be promising enhance versatility photoassisted approach. Herein, we propose photoresponsive microcapsules prepared via layer-by-layer assembly polyelectrolytes on novel CaCO3/TiO2 composite template cores. preparation particles challenging because poor compatibility TiO2 and CaCO3 in an aqueous medium. To prepare stable composites, nanoparticles...
Mineralization of hydrogel biomaterials with calcium phosphate (CaP) is considered advantageous for bone regeneration. can be both induced by the enzyme alkaline phosphatase (ALP) and promoted calcium-binding biomolecules, such as plant-derived polyphenols. In this study, ALP-loaded gellan gum (GG) hydrogels were enriched gallotannins, a subclass Five preparations compared, namely three tannic acids differing molecular weight (MW), pentagalloyl glucose (PGG), gallotannin-rich extract from...
Carbon dots (CDs) are usually used as an alternative to other fluorescent nanoparticles. Apart from fluorescence, CDs also have important properties for use in composite materials, first of all their ability absorb light energy and convert it into heat. In our work, the time, been proposed gold nanostructures harvesting energy, which results opening polymer-based containers with biologically active compounds. this paper, we propose a method synthesis polylactic acid microchamber arrays...
Microstructured optical waveguides (MOW) are of great interest for chemical and biological sensing. Due to the high overlap between a guiding light mode an analyte filling one or several fiber capillaries, such systems able provide strong sensitivity with respect variations in refractive index thickness materials. Here, we introduce novel type functionalized MOWs whose capillaries coated by layer-by-layer (LBL) approach, enabling alternate deposition silica particles (SiO2) at different...
A new type of flat substrate has been used to visualize structures inside living cells by surface-enhanced Raman scattering (SERS) and study biochemical processes within cells. The SERS is formed stabilized aggregates gold nanostars on a glass microscope slide coated with layer poly (4-vinyl pyridine) polymer. This provides good cell adhesion viability. Au nanostars’ long tips can penetrate the membrane, allowing it receive signal from biomolecules cell. proposed nanostructured surfaces were...
The article describes prospective composite biocompatible titania coatings modified with hydroxyapatite nanoparticles and obtained on intraosseous implants fabricated from commercially pure titanium VT1-00. Consistency changes of morphological characteristics, crystalline structure, physical mechanical properties biocompatibility experimental implant by the combination oxidation surface modification during induction heat treatment are defined.
A sensor based on microstructured waveguides (MWGs) with a hollow core inner surface covered polyelectrolyte-layer-stabilized gold nanostars was developed for the SERS sensing of dissolved analytes. polyelectrolyte-layer coating over glass cladding served as spacer, reducing nonlinear optical effects in near plasmonic hotspots nanoparticles, stabilizing agent thermodynamically unstable and an fine-tuning MWG bandgaps. This approach can be used to construct different kinds sensors analytes,...
In the present study a new adhesive system with embedded PVP-stabilized nano-particulate silver markers has been designed. Nanosized was used as radio-opaque contrast material in SEM examination of dentine. It studied impact fillers on rheological properties and its penetration dentine volume. A comparative evaluation resin replicas produced using nanoparticles that without ones carried out. shown embedding into did not make worse. established nanosized changed morphology. The methodology...