- COVID-19 Impact on Reproduction
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Maternal and fetal healthcare
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and Medication Impact
- Reproductive Health and Contraception
- Autoimmune Bullous Skin Diseases
- Reproductive Health and Technologies
- Prenatal Screening and Diagnostics
- Cytomegalovirus and herpesvirus research
- Parvovirus B19 Infection Studies
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- Healthcare Systems and Technology
- Ectopic Pregnancy Diagnosis and Management
- COVID-19 and healthcare impacts
- Telemedicine and Telehealth Implementation
- Neonatal Respiratory Health Research
- Urticaria and Related Conditions
- Preterm Birth and Chorioamnionitis
- Maternal Mental Health During Pregnancy and Postpartum
- Healthcare Policy and Management
- Respiratory viral infections research
Mayo Clinic in Arizona
2018-2024
Mayo Clinic
2018-2024
WinnMed
2019-2023
Community Link
2022
The University of Texas Medical Branch at Galveston
2008-2019
Dartmouth–Hitchcock Medical Center
2014-2018
Mayo Clinic in Florida
2018
Dartmouth College
2017
University of Vermont
2014-2015
University of Vermont Medical Center
2014
To investigate the extent to which antibiotic exposure in first 2 years of life is associated with risk immunological, metabolic, and neurobehavioral health conditions childhood onset.
Perinatal opioid use disorders negatively impact maternal and neonatal outcomes are a public health problem of increasing severity. More than half women with substance disorder have history posttraumatic stress that, if not adequately addressed, can impede treatment. This case report describes complexities in the treatment pregnant woman reviews psychotherapeutic pharmacologic approaches available to treat these co-occurring pregnancy. demonstrates importance early screening intervention for...
In Brief OBJECTIVE: To evaluate the presence of and estimate risk factors for reactivation latent high-risk human papillomavirus (HPV) cervical infection in immunodeficiency virus (HIV)-infected HIV-uninfected women. METHODS: Data from 898 women HIV Epidemiology Research Study (HERS) were used to HPV latency reactivation. Prior exposure types (16, 18, 31, 35, 45) was determined by serologic testing at enrollment, shedding detected polymerase chain reaction 6-month intervals. Human sexual...
Introduction Despite recommendations for COVID-19 vaccination in pregnant people, the effect of on neonatal outcomes remains unknown. We sought to determine association between status pregnancy and presence neonatally diagnosed congenital anomalies. Methods A comprehensive vaccine registry was combined with a delivery database create cohort including all patients aged 16–55 years event December 10, 2020 31, 2021 at hospital within Mayo Clinic Health System. Pregnancy were analyzed relation...
Background Hofbauer cells (HBCs) and cytotrophoblasts (CTBs) are major cell populations in placenta. The indirect impact of maternal SARS-CoV-2 disease on these that not directly infected has been extensively studied. Herein, we profiled gene expression HBCs CTBs isolated from placentae recovered pregnant subjects with during all trimesters pregnancy, active infection, vaccinated subjects, those who were unexposed to the virus. Methods Placentae collected within 4 h post-delivery...
Objective: To implement use of obstetric (OB) hospitalist telemedicine services (TeleOB) to support clinicians facing OB emergencies in low-resource hospital settings.
Intermedin (IMD) is a novel peptide expressed in trophoblast cells human placenta and enhances the invasion, migration, leukocyte antigen class I, G (HLA-G) expression first-trimester HTR-8SV/neo cells. We recently reported that infusion of IMD antagonist pregnant rats detrimental to pregnancy outcome, resulting impaired fetoplacental growth deformed placental vasculature.This study was undertaken assess its involvement implantation early placentation whether altered spontaneous abortion.We...
Abstract Despite intensive characterization of immune responses after COVID-19 infection and vaccination, research examining protective correlates vertical transmission in pregnancy are limited. Herein, we profiled humoral cellular characteristics pregnant women infected or vaccinated at different trimesters their corresponding newborns. We noted a significant correlation between spike S1–specific IgG antibody its RBD-ACE2 blocking activity (receptor-binding domain–human...
Transmission of human immunodeficiency virus (HIV) to the infant through breast-feeding is a major problem worldwide; however, biological circumstances such transmission remain unclear. Little characterization breast milk CD4(+) T lymphocytes has been done so far.We performed detailed immunophenotypic analysis in milk, compared with blood, HIV-uninfected (n=9) and HIV-infected (n=10) women receiving highly active antiretroviral therapy, by use multiparameter flow cytometry. Descriptive...
In Brief OBJECTIVE: To assess the association of 2012 New Hampshire parental notification law with patterns abortion in northern England minors. METHODS: This was a retrospective cohort study examining all minors undergoing abortions at Planned Parenthood clinics Vermont, Hampshire, and Maine from 2011 to 2012. RESULTS: The number among decreased 95 50 (47%, 95% confidence interval [CI] 37.03–57.88; P=.015) Minors residing Massachusetts, which has consent law, accounted for 62% this change....
ABSTRACT Human cytomegalovirus (CMV) glycoproteins H, L, and O (gH, gL, gO, respectively) form a heterotrimeric disulfide-bonded complex that participates in the fusion of viral envelope with host cell membrane. During virus maturation, this undergoes series intracellular assembly processing events which are not entirely defined (M. T. Huber Compton, J. Virol. 73:3886-3892, 1999). Here, we demonstrate gO does undergo same posttranslational transfected cells as it infected cells. We further...