Xin Li

ORCID: 0000-0002-3431-226X
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About
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Research Areas
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Infectious Aortic and Vascular Conditions
  • Cardiac Valve Diseases and Treatments
  • Vascular Procedures and Complications
  • Cardiac, Anesthesia and Surgical Outcomes
  • Vascular anomalies and interventions
  • Coronary Interventions and Diagnostics
  • Venous Thromboembolism Diagnosis and Management
  • Respiratory Support and Mechanisms
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Angiogenesis and VEGF in Cancer
  • Vascular Malformations and Hemangiomas
  • Abdominal vascular conditions and treatments
  • Kawasaki Disease and Coronary Complications
  • Obstructive Sleep Apnea Research
  • Periodontal Regeneration and Treatments
  • Vascular Anomalies and Treatments
  • COVID-19 Clinical Research Studies
  • Intracranial Aneurysms: Treatment and Complications
  • Cancer-related gene regulation
  • Vascular Malformations Diagnosis and Treatment
  • Renal and Vascular Pathologies
  • Peripheral Artery Disease Management
  • Nanoparticle-Based Drug Delivery

First Affiliated Hospital of Jinan University
2025

First Hospital of Jilin University
2025

Jilin University
2025

Second Xiangya Hospital of Central South University
2012-2024

Central South University
2012-2024

HM Hospitales
2024

Changsha Medical University
2024

Xiangya Hospital Central South University
2023

Weatherford College
2021

Chinese PLA General Hospital
2019

Objective . The P2Y 6 receptor has been shown to be involved in many cardiovascular diseases, including hypertension and atherosclerosis. study is aimed at exploring the role of Ang II-induced abdominal aortic aneurysm (AAA) formation apolipoprotein E-deficient (apoE -/- ) mice by using its selective antagonist. Methods Male apoE were fed with high-fat diet infused angiotensin (Ang) II (1000 ng/kg/min) for 4 weeks induce AAA or saline as controls. Mice divided into four groups: normal (NS,...

10.1155/2020/1983940 article EN cc-by BioMed Research International 2020-04-18

Revascularization of the supra-aortic major branches in thoracic endovascular aortic repair (TEVAR) is challenging owing to complex anatomic configuration arch pathologies. This study aims evaluate feasibility, effectiveness, and safety three techniques-chimney, fenestrated, in-situ fenestration-for patients with pathologies.A retrospective analysis was performed involving 234 lesions, who underwent TEVAR adaptations technique (chimney, or fenestration) between January 2016 December 2017.One...

10.21037/jtd.2020.03.10 article EN Journal of Thoracic Disease 2020-04-01

Vascular smooth muscle cells (VSMCs) undergo cell biological changes in response to a variety of cytokines and growth factors. Adiponectin inhibits neointimal formation through suppressing the proliferation migration VSMCs. However, mechanisms underlying effect adiponectin on VSMC apoptosis require further investigation. The present study was designed investigate apoptosis, focusing mitofusin‑2 (MFN2) mediated Ras‑Raf‑extracellular signal regulated kinase (Erk)1/2 signaling pathway. results...

10.3892/mmr.2015.3899 article EN Molecular Medicine Reports 2015-06-08

Background: This study aimed to evaluate the perioperative outcomes of concomitant coronary artery bypass grafting (CABG) in patients undergoing surgical repair for acute type A aortic dissection (ATAAD) and assess impact CABG on mortality complications. Methods: retrospective analysis was conducted 1198 ATAAD who underwent treatment at our center between January 2016 December 2022. Patients were categorized into non-CABG groups. Preoperative characteristics, data, collected analyzed....

10.59958/hsf.8079 article EN The Heart Surgery Forum 2025-01-20

With the maturity of thoracic endovascular aortic repair (TEVAR) technology and its increasing application in clinical practice, complications long-term management after TEVAR have become issues concern. Here, we report two cases for dissection. One patient developed recurrent fever 6 years underwent multiple courses antibiotic therapy with a poor response. He came to our hospital months later presented gastrointestinal bleeding. Imaging revealed presence an abscess around stent graft...

10.3389/fcvm.2025.1549613 article EN cc-by Frontiers in Cardiovascular Medicine 2025-02-25

Abstract Background: In the recent outbreak of novel coronavirus infection worldwide, risk thrombosis and bleeding should be concerned. Objectives: We aimed to observe dynamic changes D-dimer levels during disease progression evaluate their value for thrombosis. Methods: this study, we report clinical laboratory results 57 patients with confirmed COVID-19 pneumonia 46 community-acquired bacterial (CAP). And concentrations D-dimer, infection-related biomarkers, conventional coagulation were...

10.21203/rs.3.rs-20056/v1 preprint EN cc-by Research Square (Research Square) 2020-03-31

Purpose: To evaluate the safety and feasibility of in situ needle fenestration (ISNF) technique for reconstruction left subclavian artery (LSA) during thoracic endovascular aortic repair (TEVAR) complicated arch pathologies. Materials Methods: A retrospective review was conducted from January 2014 to December 2019 50 patients (mean age 60.2±11.1; 45 men) who underwent ISNF revascularize LSA TEVAR. Twenty-one also required revascularization common carotid (LCCA; n=19) innominate (IA; n=2)...

10.1177/1526602820953406 article EN Journal of Endovascular Therapy 2020-09-01

Shivering associated with spinal anesthesia during Cesarean delivery is an uncomfortable experience for the parturient, which may also cause adverse effects. In this prospective, randomized, double-blind, placebo-controlled study, we sought to evaluate effect of intrathecal dexmedetomidine, administered as adjunct hyperbaric bupivacaine delivery, on incidence and severity shivering anesthesia. Patients undergoing were randomly allocated three groups 30 patients each. Experimental treatments...

10.1248/bpb.b16-00651 article EN Biological and Pharmaceutical Bulletin 2017-01-01

When performing thoracic aortic endovascular repair (TEVAR) on lesions of the arch, physician-modified fenestration or in situ is often used to maintain patent branches.We designed a new adjustable prefenestration stent graft that can both isolate pathologies arch and obtain branches simultaneously.In this study, we use type perform fenestrated TEVAR canine's aorta.This study aims evaluate safety feasibility device, which may provide preliminary data for potential human application....

10.4274/dir.2023.232440 article EN cc-by-nc Diagnostic and Interventional Radiology 2024-02-01

Background: This study aimed to analyze the clinical characteristics and treatment response of patients with chronic obstructive pulmonary disease (COPD) low body mass index (BMI). Methods: In this cross-sectional study, we enrolled stable COPD from database setup by Second Xiangya Hospital Central South University. We classified into three groups based on BMI: low-BMI (<18.5 kg/m2), normal-BMI (≥18.5 <24.0 high-BMI (≥24 kg/m2) groups. defined clinically important deterioration (CID) as a...

10.3389/fphar.2023.1131614 article EN cc-by Frontiers in Pharmacology 2023-07-13

Gadolinium-based MR cisternography has been mainly applied in clinical evaluation of cerebrospinal fluid leaking, that is conducted by intrathecal administration contrast media. Recently, we have reported one novel technique targeted drug delivery with prepontine cisternal routine to treat orofacial cancer pain. The aim this study was examine the distribution pattern strategy. Here, introduce case who suffered severe pain caused sublingual gland tumor, and successfully attenuated analgesic...

10.1080/10717544.2023.2189588 article EN cc-by Drug Delivery 2023-03-17

Sclerotherapy has achieved great success in treating most venous malformation (VM) lesions.To compare the effects of foam sclerotherapy on infantile hemangioma and pyogenic granuloma (PG). In addition, we analyzed data outcomes for VM.Thirty-nine patients with hemangiomas 83 VMs were treated, clinical outcomes, resolution, complication rates compared. from VM group also analyzed.The average age distribution tissue involvement lesions among 3 groups significantly different ( p < .001). The...

10.1097/dss.0000000000003857 article EN Dermatologic Surgery 2023-07-10
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