A5078629397- Systemic Sclerosis and Related Diseases
- Sarcoidosis and Beryllium Toxicity Research
- Rheumatoid Arthritis Research and Therapies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Spondyloarthritis Studies and Treatments
- Vasculitis and related conditions
- Bone and Joint Diseases
- Inflammatory Myopathies and Dermatomyositis
- Gout, Hyperuricemia, Uric Acid
- Oral Health Pathology and Treatment
- Ocular Diseases and Behçet’s Syndrome
- Eosinophilic Disorders and Syndromes
- Oral microbiology and periodontitis research
- Urticaria and Related Conditions
- Autoimmune and Inflammatory Disorders Research
- Parasitic infections in humans and animals
- Protease and Inhibitor Mechanisms
- Peripheral Neuropathies and Disorders
- Infectious Diseases and Tuberculosis
- Salivary Gland Disorders and Functions
- HIV/AIDS oral health manifestations
- Retinal and Optic Conditions
- Musculoskeletal synovial abnormalities and treatments
- Systemic Lupus Erythematosus Research
- Otitis Media and Relapsing Polychondritis
Kyung Hee University
2012-2025
Kyung Hee University Medical Center
2012-2024
Seoul National University Bundang Hospital
2015-2019
Creative Commons
2019
Kyung Hee University Hospital at Gangdong
2012-2017
To explore the course of lung function and RA disease activity predictive factors for deteriorating in patients with RA-interstitial (ILD).The Korean Rheumatoid Arthritis-Interstitial Lung Disease cohort is a multicentre, prospective observational cohort. Patients RA-ILD were enrolled followed up annually 3 years ILD status assessment. Group-based modelling was used to cluster similar predicted percentage forced vital capacity (FVC%) patterns into trajectories.This study included 140 who...
Objective To investigate baseline and change of pulmonary damage biomarkers (serum Krebs von den Lungen 6 [KL-6], human surfactant protein D [hSP-D], matrix metalloproteinase 7 [MMP-7]) with rheumatoid arthritis–associated interstitial lung disease (RA-ILD) progression. Methods In the Korean Rheumatoid Arthritis Interstitial Lung Disease (KORAIL) cohort, a prospective we enrolled patients RA ILD confirmed by chest computed tomography imaging followed annually. progression was defined as...
The human oral microbiome refers to an ecological community of symbiotic and pathogenic microorganisms found in the cavity. cavity is a suitable environment that provides various kinds biological niches such as teeth, tongue, mucosa. gateway between external body, maintaining homeostasis, protecting mouth, preventing disease. On flip side, plays important role triggering, development, progression systemic diseases. Currently, disease diagnosis through analysis has been realized with recent...
Abstract Objective To examine the association between MTX, LEF and tacrolimus use progression of RA-associated interstitial lung disease (ILD). Methods The Korean RA-ILD cohort prospectively enrolled patients with ILD at multiple centres from 2015 to 2018 followed up them for 3 years. was defined by any followings: a decrease ≥10% in forced vital capacity, ≥15% diffusing capacity carbon monoxide, or death respiratory failure. Results Of 143 patients, 64 experienced during median follow-up...
Semaphorin 3A (Sema3A) and semaphorin 4D (Sema4D) are molecules which regulate immune responses as well bone remodeling process. The aim of this study was to evaluate the serum levels Sema3A Sema4D investigate their clinical significance in rheumatoid arthritis (RA). were measured 130 patients with RA 65 sex- age-matched healthy individuals. Circulating biomarkers RA-related inflammation turnover such tumor necrosis factor- (TNF-) α , interleukin- (IL-) 6, IL-22, IL-34, osteopontin, Dkk-1,...
Abstract Rheumatoid arthritis (RA) and osteoarthritis (OA) are two different types of arthritis. Within RA, the subsets between seronegative RA (snRA) seropositive (spRA) represent distinct disease entities; however, identifying clear distinguishing markers them remains a challenge. This study investigated compared oral health conditions in patients with OA to clarify differences from healthy controls. In addition, we serological characteristics patients, factors that distinguished those OA,...
Neuro-Behçet's disease (NBD) represents a significant complication of Behçet's syndrome, potentially leading to elevated mortality and disability rates. The standard treatment for parenchymal NBD typically entails administering high-dose corticosteroids prompt rapid-onset effects, coupled with immunosuppressants prevent subsequent relapses. A 48-year-old male presented progressively worsening dysarthria over 9 months. This patient experienced increased intraocular pressure while using...
Sparganosis in humans is an incidental infection and known to be associated with eating insufficiently cooked meat of frogs snakes or drinking unboiled stream water. Although it can involve various internal organs, pulmonary pleural involvement due sparganum rare. Because we recently experienced two cases involving lung parenchyma pleura that were misdiagnosed as bacterial pneumonia cancer, herein intend present them detail.
This study aimed to investigate the inf luence of poor sleep quality on clinical features primary Sjögren's syndrome (pSS).Sleep was cross-sectionally assessed using Pittsburgh Sleep Quality Index (PSQI), and demographic, clinical, laboratory data were collected from 115 Korean patients with pSS. The completed questionnaires European League Against Rheumatism (EULAR) SS Patient Reported (ESSPRI), life (EuroQOL five dimensions questionnaire [EQ-5D]), fatigue (fatigue severity score [FSS]),...
Hip pain is a common musculoskeletal complaint in general practice. Although comprehensive diagnostic approach on hip mandatory for adequate treatment, un- or mis-diagnosis not rare primary care. The aim of this study was to analyze descriptively mis-diagnosed cases referred from care tertiary hospital, especially young adults ≤ 50 years old.We retrospectively analyzed consecutive cohort 150 patients (≤ old) with chronic (≥ 6 weeks), which diagnosed misdiagnosed based the information...
Introduction and objective Ankylosing spondylitis (AS) has characteristics of spinal bone bridge fusion. Although BMD reduction in AS may be presumed to due inflammation, this study was designed confirm whether immobilization the spine syndesmophytes is related reduction, as itself a risk factor for reduction. Methods Among male patients diagnosed with according modified New York criteria, those who underwent density tests quantitative computed tomography (QCT) were retrospectively analyzed...
Abstract Aim This study aimed to investigate the clinical features and risk factors of gout attacks during anti‐tuberculosis (TB) treatment in South Korea. Method We investigated characteristics 49 patients who suffered from while taking anti‐TB medications. Among them, 25 TB having newly developed without prior history were set group. Seventy‐five age‐ sex‐matched therapy randomly selected as control The demographics, features, laboratory findings between two groups compared establish...
Spondyloepiphyseal dysplasia (SED) tarda is an inherited skeletal arthropathy. Because SED involves the joints and resemble clinical findings of chronic arthropathies, this disease frequently misdiagnosed as juvenile idiopathic arthritis (JIA). We report here on three patients (father his two daughters) in one family with tarda. All had back pain polyarthralgia. Their radiographs revealed typical changes for including platyspondyly dysplastic bone changes. This rare has major importance that...
To investigate correlations between myositis-specific autoantibodies (MSA) or myositis-associated antibodies (MAA) and clinical features, thereby demonstrating the utility of clinicoserologic classification in idiopathic inflammatory myopathies (IIM) patients.We conducted a multicenter study 108 adult patients (age ≥18 years) who were diagnosed with IIM by Peter Bohan criteria 2004 European Neuromuscular Centre (ENMC) criteria. Clinical data obtained medical record review. Immunoblot assay...
BACKGROUND To elucidate the achievement rates of imaging remission and to examine characteristics associated with status among patients rheumatoid arthritis (RA) who have attained clinical remission. METHODS Ninety-seven RA had remission, defined by DAS28-ESR < 2.6 were enrolled. Power Doppler ultrasonography (PDUS) was performed on 16 joints 2 tendons, including first third metacarpophalangeal, second proximal interphalangeal, radiocarpal (RC), metatarsophalangeal joints, extensor carpi...
Granulomatosis with polyangiitis (GPA) is an autoimmune disease which a type of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis that frequently affects the lungs and kidneys. However, GPA limited to single organ has also been reported. A 71-year-old man was admitted for back pain fever. We detected elevated levels inflammatory markers myeloperoxidase-ANCA. Magnetic resonance imaging indicated diffuse inflammation psoas muscles. Histology showed degenerated muscle fibers...
Sparganosis in humans is an incidental infection and known to be associated with eating insufficiently cooked meat of frogs snakes or drinking unboiled stream water. Although it can involve various internal organs, pulmonary pleural involvement due sparganum rare. Because we recently experienced two cases involving lung parenchyma pleura that were misdiagnosed as bacterial pneumonia cancer, herein intend present them detail.
Background and Objective: Rheumatoid arthritis (RA) is an autoimmune disease in which joints are gradually destroyed. Early diagnosis treatment before joint deformation or destruction important. The detection of novel RA biomarkers saliva may facilitate early onset. This study aimed to evaluate salivary concentration α1-antitrypsin (A1AT) healthy patients those with RA, assess the diagnostic value A1AT. Materials Methods: In total, 80 participants were included: 20 participants, 60 RA....