- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Hearing, Cochlea, Tinnitus, Genetics
- Periodontal Regeneration and Treatments
- Mesenchymal stem cell research
- Vestibular and auditory disorders
- Hearing Loss and Rehabilitation
- Tissue Engineering and Regenerative Medicine
- Glioma Diagnosis and Treatment
- Vagus Nerve Stimulation Research
- Medical Imaging Techniques and Applications
- Biochemical effects in animals
- Cerebrovascular and Carotid Artery Diseases
- Brain Metastases and Treatment
- Bone fractures and treatments
- Diverticular Disease and Complications
- Anorectal Disease Treatments and Outcomes
- Neurological Disease Mechanisms and Treatments
- Sleep and Wakefulness Research
- Radiation Dose and Imaging
- Colorectal and Anal Carcinomas
- Sleep and related disorders
- Moyamoya disease diagnosis and treatment
First Affiliated Hospital of Jiamusi University
2025
Shanghai Public Health Clinical Center
2024
Shanghai University of Traditional Chinese Medicine
2024
Seventh People's Hospital of Shanghai
2024
Southern Medical University
2021-2023
Shandong University
2011-2021
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2021
Center for Excellence in Brain Science and Intelligence Technology
2021
Shenzhen Institutes of Advanced Technology
2021
Seoul National University Bundang Hospital
2020
Mesenchymal stem cells (MSCs) have been considered promising tools for tissue engineering and regenerative medicine. However, the optimal cell source bone regeneration remains controversial. To better identify seed engineering, we compared MSCs from seven different tissues, including four dental origins, pulp (DPSCs), periodontal ligament (PDLSCs), gingival (GMSCs), follicle (DFSCs); two somatic marrow-derived (BM-MSCs) adipose-derived (ADSCs); one birth-associated perinatal umbilical cord...
Presbycusis (PC) is characterized by bilateral sensorineural hearing loss at high frequencies and speech-perception difficulties in noisy environments has a strikingly detrimental impact on cognitive function. As the neural consequences of PC may involve whole brain, we hypothesized that patients with would show structural alterations not only auditory cortex but also cortexes involved The purpose this study was to use surface-based morphometry (SBM) analysis elucidate whole-brain...
Rutin is one of the flavonoids found in fruits and vegetables. Recent reports have revealed that rutin a major player proliferation bone development. However, data on how regulates periodontal ligament stem cells (PDLSCs), as well differentiation osteogenic are scanty. Here, our findings showed enhanced PDLSCs proliferation, increased ALP activity, matrix mineralization. Moreover, significantly promoted expression genes elevated phosphorylated AKT mTOR. Treatment with LY294002 reversed these...
Abstract Introduction Subcortical vascular mild cognitive impairment (sv MCI ) is the predementia stage of subcortical dementia ( SV aD). The aim this research to explore and compare cerebral gray matter GM volume reduction in sv patients aD patients, investigate relationship between deficits. Methods Thirty one 29 31 healthy controls were recruited our research. They conducted neuropsychological tests brain structural magnetic resonance imaging MRI examination. To detect we used statistical...
Background To investigate the asymmetry of quantitative cerebral blood flow (CBF) values in interictal temporal lobe epilepsy (TLE) patients with (TLE‐MTS) and without (TLE‐no) mesial sclerosis. Methods Twenty‐six TLE (14 TLE‐MTS/12 TLE‐no) 22 controls were studied a three‐dimensional whole‐brain pseudocontinuous arterial spin‐labeling technique at 3.0 Tesla. Regions interest placed bilateral hippocampal heads, amygdalas lobes to get average regional (rCBF) calculate indices (AIs)....
The primary importance of magnetic resonance (MR) imaging in evaluating anal fistulas lies its ability to demonstrate hidden areas sepsis and secondary extensions patients with fistula ano. MR is relatively expensive, so there are many healthcare systems worldwide where access remains restricted. Until recently, computed tomography (CT) has played a limited role ano, largely owing poor resolution soft tissue. In this article, the different features CT MRI compared relative accuracy...
There is growing evidence for dysfunctional glutamatergic excitation and/or gamma‐aminobutyric acid (GABA)ergic inhibition in patients with multiple sclerosis (MS). Cognitive impairment may occur during the early stages of MS and hippocampal abnormalities have been suggested as biomarkers. However, researchers not clearly determined whether changes GABA glutamate (Glu) levels are associated cognitive aberrant neural activity MS. We used magnetic resonance spectroscopy to measure GABA+ Glu...
The tertiary lymphoid structures (TLSs) are positively correlated with the prognosis of many solid tumors, including colorectal cancer. However, their prognostic significance in patients locally advanced rectal cancer (LARC) after neoadjuvant chemotherapy remains unclear. This study aimed to explore correlation between TLS parameters and LARC receiving chemotherapy. retrospective included treated at Harbin Medical University Cancer Hospital from 2012 2021. quantity, area, density TLSs tumor,...
Background and Objective Mesenchymal stem cells ( MSC s) have been widely used in tissue engineering, such as for regenerating the supporting structures of teeth destroyed by periodontal diseases. In recent decades, dental tissue‐derived s drawn much attention owing to their accessibility, plasticity applicability. Dental pulp DPSC s), ligament PDLSC gingival GMSCs ) are most readily available among all types s. The purpose this study was comprehensively compare characteristics from DP ),...
<h3>BACKGROUND AND PURPOSE:</h3> Presbycusis is the most common sensory deficit in aging population. A recent study reported using a DTI-based tractography technique to identify lack of integrity portion auditory pathway patients with presbycusis. The aim our was investigate white matter pathology presbycusis by voxel-based analysis that highly sensitive local intensity changes DTI data. <h3>MATERIALS METHODS:</h3> Fifteen and 14 age- sex-matched healthy controls were scanned on 3T scanner....
Presbycusis (PC) is associated with cognitive decline and incident dementia. Speech reception thresholds (SRT) are used to assess speech detection, which points toward a central component of PC. However, our knowledge, no previous study has reported the relationship between SRT function in older adults Han Chinese cohort. Therefore, this study, we investigate association hearing loss, indexed using pure tone average (PTA) SRT, cohort standardized neurocognitive battery. Subjects (aged ≥ 60...
<h3>BACKGROUND AND PURPOSE:</h3> The differential diagnosis of radionecrosis and tumor recurrence in brain metastases is challenging. We investigated the diagnostic efficiency postcontrast T1 mapping solving this problem. <h3>MATERIALS METHODS:</h3> Between March 2016 June 2017, fifty-six patients with who underwent contrast-enhanced cerebral were recruited for prospective study. findings revealed new enhancement after gamma knife radiosurgery. subjects assigned to groups based on follow-up...
<h3>BACKGROUND AND PURPOSE:</h3> Systematic and accurate glioma grading has clinical significance. We present the utility of multi-TI arterial spin-labeling imaging provide bolus arrival time maps for astrocytomas. <h3>MATERIALS METHODS:</h3> Forty-three patients with astrocytomas (21 men; mean age, 51 years) were recruited. The classification abilities conventional MR features, normalized CBF value derived from imaging, time, single-TI compared in World Health Organization (WHO) grade II,...
This study aimed to explore the potential of magnetic resonance imaging (MRI) radiomics-based machine learning improve assessment and diagnosis contralateral Breast Imaging Reporting Data System (BI-RADS) category 4 lesions in women with primary breast cancer.A total 178 BI-RADS (97 malignant 81 benign) collected from cancer patients were involved our retrospective dataset. T1 + C T2 weighted images used for radiomics analysis. These randomly assigned training (n = 124) dataset an...
Abstract As a representative of acupuncture and nonpharmaceutical therapy, auricular has been widely for the treatment insomnia. Transcutaneous vagus nerve stimulation (taVNS) is combination point stimulation. It can not only treat primary insomnia effectively, but also noninvasive, painless, portable economical. The medial prefrontal cortex (mPFC) core region default mode network (DMN), which important maintenance sleep. However, mechanism taVNS in alleviating (PI) remains to be clarified....
Background: Thyroidectomy is commonly performed for benign or malignant thyroid tumors, often resulting in hypothyroidism.Levothyroxine (LT4) supplementation crucial to maintain hormone levels within the normal range and suppress TSH cancer control.However, determining optimal dosage remains challenging, leading uncertain outcomes potential side effects.Methods: We analyzed clinical examination data from 510 total thyroidectomy patients, including demographic information, blood tests,...