A5100435775- Vagus Nerve Stimulation Research
- Acupuncture Treatment Research Studies
- EEG and Brain-Computer Interfaces
- Healthcare and Venom Research
- Heart Rate Variability and Autonomic Control
- Complementary and Alternative Medicine Studies
- Myofascial pain diagnosis and treatment
- Neuroscience and Neural Engineering
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Neuroinflammation and Neurodegeneration Mechanisms
- Sperm and Testicular Function
- Sleep and related disorders
- COVID-19 and Mental Health
- Neurological disorders and treatments
- Nicotinic Acetylcholine Receptors Study
- Colorectal Cancer Treatments and Studies
- Olfactory and Sensory Function Studies
- Botulinum Toxin and Related Neurological Disorders
- Obsessive-Compulsive Spectrum Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- High Altitude and Hypoxia
- Sodium Intake and Health
- Colorectal Cancer Surgical Treatments
- Respiratory Support and Mechanisms
Sichuan University
2025
West China Hospital of Sichuan University
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2008-2024
China Academy of Chinese Medical Sciences
2011-2023
China Association of Acupuncture-Moxibustion
2020-2023
Xiyuan Hospital
2022
Ningxia Medical University
2021
University of Hong Kong
2020
Chinese University of Hong Kong
2020
Beijing University of Chinese Medicine
2015-2019
There are 9.9 million new cases of dementia in the world every year. Short-term conversion rate from mild cognitive impairment (MCI) to is between 20% and 40%, but long-term 5-10 years ranges 60% 100%. It particularly important prevent or prolong development MCI into dementia. Both auriculotherapy vagus nerve stimulation effective on improving functions. However, there no double blinded randomized clinical trial support effectiveness transcutaneous electrical auricular acupoints patients...
This study sought to explore the characteristics of de qi using electroacupuncture at acupoints with different properties in meridian category, histological type, and nerve innervations.Electroacupuncture was performed on 21 healthy volunteers paired ST36-GB34, CV4-CV12, ST36-ST28, PC6-PC7, ST36-CV4. Upon acupuncture qi, intensities prevalence individual sensations, sensation transmission, amplitude electrical current were recorded. Chi-square, Fischer's exact test, Wilcoxon two-sample t...
To estimate the long-term effect of changing demography in China on blood supply and demand.We developed a predictive model to demand during 2017-2036 mainland 31 province-level regions. Model parameters were obtained from World Population Prospects, statistical yearbook 2016, China's report safety records large tertiary hospital. Our main assumptions stable age-specific per capita over time.We estimated that change demographic structure between 2016 (baseline year) 2036 would result 16.0%...
IMPORTANCE Evidence from randomized clinical trials of transcutaneous auricular vagus nerve stimulation (taVNS) for chronic insomnia disorder is lacking. OBJECTIVE To evaluate the efficacy and safety taVNS compared with sham taVNS. DESIGN, SETTING, PARTICIPANTS This trial was conducted October 2021 to December 2022 at a single center in Beijing, China. Patients Pittsburgh Sleep Quality Index (PSQI) least 8 were enrolled. Statistical analysis performed June September 2023. INTERVENTIONS...
Abstract As a representative of acupuncture and nonpharmaceutical therapy, auricular has been widely for the treatment insomnia. Transcutaneous vagus nerve stimulation (taVNS) is combination point stimulation. It can not only treat primary insomnia effectively, but also noninvasive, painless, portable economical. The medial prefrontal cortex (mPFC) core region default mode network (DMN), which important maintenance sleep. However, mechanism taVNS in alleviating (PI) remains to be clarified....
Mortality outcomes in trials of low-dose computed tomography (CT) screening for lung cancer are inconsistent. This study aimed to evaluate whether CT urban areas China could reduce mortality and investigate the factors that associate with effect. A decision tree model three scenarios (low-dose screening, chest X-ray no screening) was developed compare results a simulated Chinese cohort (100,000 smokers aged 45–80 years). Data participant characteristics were obtained from national registries...
fMRI studies showed that acupuncture could induce hemodynamic changes in brain networks. Many of these focused on whether specific acupoints activate regions and were often limited to manual at the limbs. In this study, we investigated acupuncture's modulation effects functional networks by electroacupuncture (EA) midline abdomen. Acupoints Guanyuan (CV4) Zhongwan (CV12) stimulated 21 healthy volunteers. The needling sensations, activation, connectivity studied. We found limbic-prefrontal...
Yiqi Jiedu (YQJD) decoction is a Chinese herbal prescription, based on an experienced expert of traditional medicine. It used for the injuries caused by radiotherapy. The current study was designed to investigate protective effects YQJD radiation damage testis in mice, and explore its potential mechanisms.Mice were randomly divided into blank control group (Ctrl), model (IR), positive drug (IRA), (IRY). After 10-day period intervention, they whole-body irradiated with 2 Gy 60Co γ-rays...
Basic and clinical research on auricular acupuncture points (AAPs) was performed in China, the United States, France Germany. Clinical point (AAP) done Italy, Austria, Switzerland, Spain, UK, Holland, Japan, Russia, Africa. This paper is aimed at investigating similarities of WFAS standard European system AAPs according to Nogier Bahr. Similarities were analyzed from perspective name location points, taking standards World Federation Acupuncture-Moxibustion Societies (WFAS)-Auricular...
Abstract A review was undertaken of the operation process and development transcutaneous electrical acupoint stimulation (TEAS) related devices for TEAS, with aim to offer a reference developing an international standard basic safety essential performance devices. The articles TEAS instruction were searched using EMBASE, MEDLINE, Web Science databases time period from inception July 18, 2023. In absence parameter description stimulators, multimeter used measure output voltage, resistance,...
To evaluate the effects that inhalation of combustion products traditional Chinese herb Aiye (Folium Artemisiae Argyi) has on central nervous system.Forty Kunming mice (half male) were randomly assigned (n = 10/group) to a control group (C) or one three moxa smoke concentration groups (% opacity): low (L1; 0.4% ), medium (M1; 2% and high (H1; 15% ). Mice in latter exposed dynamic gas exposure cabinet for 20 min per day 7 days. placed same without any intervention. For sleep experiments,...
Objectives To explore the effect of interaction between ACE genotype and salt intake on hypertension among Chinese Kazakhs, to compare applications interactions logistic model generalised partially linear tree-based regression (GPLTR) model. Design Population-based cross-sectional study. Setting Hong Dun, North Xinjiang, China. Participants Non-consanguineous Kazakh participants (n=916, 342 men 574 women) aged ≥30 years. Main outcome measures Association hypertension, association in two...
Moxibustion is a complementary therapy that has been used for thousands of years. Burning moxa produces smoke and inhalable particulates. Recent research indicated inhalation associated with negative lung effects. This study aimed to evaluate the function rats after exposure at different concentrations.Using randomised block experiment design, 28 male Wistar were randomly divided into three groups (opacity) (n=7): low concentration (27.45 mg/m3), medium (168.76 high (384.67 mg/m3) control...
Moxibustion is commonly used as a traditional Chinese medicine treatment. The aim was to investigate how the exposure of moxa smoke influences sperm parameters, testis index and serum sex hormones in Wistar male rats. 48 rats were randomly assigned, n = 12/group, control group or one three moxa-smoke groups: M1 (low concentration, 0.4% optical density), M2 (middle 2%) M3 (high 15%). Rats groups exposed at respective concentrations (0.4% (2%) (15%) for 12 weeks, 5 days per week 200 min day....
Objective: To access the comparative effectiveness and safety of different oral Chinese patent medicine (OCPM) versus oxaliplatin-based chemotherapy regimen (C) alone for colorectal cancer (CRC) through network meta-analysis (NMA). Methods: Several electronic databases were searched randomized controlled trials (RCTs) concentrated on use OCPM to treat CRC with C from inception January 10, 2021. We performed frequentist NMA indirect comparison compare study outcomes included RCTs. The risk...
Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on comprehensive analysis of the complex mAbs. This firstly utilized fit with single-dose plasma concentration data bevacizumab in beagle dogs receiving an intravenous administration 2.5 mg/kg bevacizumab. Then, optimal PK parameters from...
Background: Transcutaneous auricular vagus nerve stimulation (taVNS) is effective for treating major depressive disorder (MDD). We aimed to explore the modulating effect of prolonged longitudinal taVNS on striatal subregions’ functional connectivity (FC) in MDD patients. Methods: Sixteen patients were enrolled and treated with 8 weeks. healthy control subjects (HCs) recruited without intervention. The resting-state FC (rsFC) based subregion seed points Hamilton Depression Scale (HAMD)...