A5016290459- Dementia and Cognitive Impairment Research
- Neurological Disease Mechanisms and Treatments
- Cognitive Functions and Memory
- Health, Environment, Cognitive Aging
- Sepsis Diagnosis and Treatment
- Neurological Disorders and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Alzheimer's disease research and treatments
- EEG and Brain-Computer Interfaces
- Sleep and Wakefulness Research
- Acute Kidney Injury Research
- Occupational health in dentistry
- Health Systems, Economic Evaluations, Quality of Life
- Hemodynamic Monitoring and Therapy
- Vagus Nerve Stimulation Research
- Spatial Neglect and Hemispheric Dysfunction
- Nutritional Studies and Diet
- Bioinformatics and Genomic Networks
- Functional Brain Connectivity Studies
- Musculoskeletal pain and rehabilitation
- Ergonomics and Musculoskeletal Disorders
Capital Medical University
2017-2022
Chinese Institute for Brain Research
2017
National Clinical Research Center for Digestive Diseases
2017
There are 9.9 million new cases of dementia in the world every year. Short-term conversion rate from mild cognitive impairment (MCI) to is between 20% and 40%, but long-term 5-10 years ranges 60% 100%. It particularly important prevent or prolong development MCI into dementia. Both auriculotherapy vagus nerve stimulation effective on improving functions. However, there no double blinded randomized clinical trial support effectiveness transcutaneous electrical auricular acupoints patients...
Substantial studies have reported the prevalence and affecting factors of subjective cognitive decline (SCD). The complaints screening scale has also been used for probing. However, little is known in China.To investigate risk SCD, explore an SCD China.Stratified cluster random sampling was conducted. 2,689 residents aged 60-80 years completed questionnaire 1. 814 were included clinical neuropsychological evaluations. Two standards to make diagnosis mild impairment (MCI) a preliminary rate...
Abstract Acute kidney injury (AKI) is a serious complication in the intensive care unit (ICU), which may increase mortality of critically ill patients. The red blood cell distribution width (RDW) has proved useful as predictor short-term prognosis patients with AKI. However, it remains unknown whether RDW prognostic value long-term all-cause these data 18279 AKI at first-time hospital admission were extracted from Medical Information Mart for Intensive Care III (MIMIC-III) database. tertiles...
Abstract Background Since SCD ( plus ) was standardized, little is known about its demographic characteristics and outcomes of neuropsychological assessments, including the questionnaire 9 (SCD‐Q9). Objective To characterize by comparing features among subgroups with normal controls (NC). Also, to explore demographics understand relation chief complaints scores SCD‐Q9. Methods Multistage stratified cluster random sampling conducted select participants. As a result, 84 NC 517 were included....
Background: Since subjective cognitive decline (SCD) was standardized in 2014, there have been few studies reporting the risk factors and neuropsychological assessment characteristics of SCD (plus) memory clinic. Objective: To characterize by comparing it with normal control (NC), amnesic mild impairment (aMCI), Alzheimer Disease (AD) regarding their demographics, lifestyle, family history dementia, multimorbidity assessments. Methods: A total 135 participants were recruited, including 23...
Growing industrialization of China exposes its labor population to the risk musculoskeletal disorders (MSDs). This study aimed investigate prevalence and factors MSDs in a modern industrial region Beijing.A cross-sectional included 1415 employees six companies was conducted between January 2018 May Fangshan district, Beijng, China. Nordic Musculoskeletal Questionnaire (NMQ) used collect information about MSDs. Demographic factors, lifestyle health medical work-related were collected as...
Objective: Subjective cognitive decline (SCD) complaints as the early manifestation of mild impairment (MCI) may be harbingers objective decline. SCD-questinnaire9 (SCD-Q9) is developed to investigate sign for MCI. However, few studies have reported its power discriminating MCI from healthy controls (HCs). Therefore, this study aims discrimination SCD-Q9 a brief screening tool detection SCD in MCI.Methods: 84 HCs and 205 people with were recruited. Their demographic information scores...
Subjective cognitive decline-questionnaire 9 (SCD-Q9) was developed to detect SCD complaints at risk of mild impairment (MCI). However, our previous findings indicated that its coverage might be insufficient. To test this hypothesis, we recently translated SCD-Q21.To examine the reliability and validity SCD-Q21 explore effectiveness for discriminating MCI from controls.Item analysis performed understand item discrimination homogeneity. The Cronbach's α Spearman-Brown's split-half...
Background: Several severity scales have been documented to predict the short-term mortality of septic patients. However, predictive efficacies different in long-term elderly yet be evaluated.Methods: In retrospective study, a cohort 4,370 (≥65 years) patients admitted intensive care unit (ICU) were divided into three age groups, i.e., younger-old group (65 years ≤ <75 years), older-old (75 <85 and oldest-old (age ≥85 years). Five scales, including Simplified Acute Physiology Score II (SAPS...
Previous reports on APOE ε4 allele distribution in different populations have been inconclusive. The Subjective Cognitive Decline-Questionnaire 9 (SCD-Q9) was developed to identify those at risk of objective cognitive impairment [OCI; including mild (MCI) and dementia groups), but its association with discriminatory powers for SCD subtle decline (SCDs) OCI memory clinics are unclear.To investigate demographic ε4, SCD-Q9 scores, ability discriminate SCDs groups from normal control (NC).A...
Substantial studies have reported the prevalence and affecting factors of SCD complainants screening scale has also been used for probing. However, little is known about due to AD in eastern countries, especially China where subjective cognitive complainant not yet applied. Stratified cluster random sampling was conducted, 2688 residents 60–80 years completed questionnaire 1 814 were eventually included clinical neuropsychological evaluations. Two standards make diagnosis MCI SCD, a...
To investigate the prevalence rate and risk factors of features in subjective cognitive decline (SCD-plus) Beijing. Stratified cluster random sampling was conducted ShunYi District 16 committees from September to November 2016. The potential patients with SCD were surveyed questionnaires. According inclusion exclusion criteria, 713 non-dementia participants finally included statistical analysis. After excluding MCI which diagnosed by both Petersen Jack/Bondi or normal control (NC). average...
To explore the effects of ApoE epsilon4 (ApoE-ε4) alleles on cognitive function and resting state functional MRI in patients with amnestic mild impairment(aMCI) based a prospective cohort study. An average more than 20 months observations was conducted 22 ApoE-ε4-carriers 31 non-carriers aMCI. Neuropsychological assessments resting-state MRI(rs-fMRI) data were acquired respectively at baseline follow-up. Comparison conversion rate dementia between nonsε4-carriers Meanwhile, seed-based...