Xin Chen

ORCID: 0000-0001-7958-8107
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About
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Research Areas
  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Urological Disorders and Treatments
  • Meningioma and schwannoma management
  • Urinary Bladder and Prostate Research
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Gastrointestinal disorders and treatments
  • Cardiac Valve Diseases and Treatments
  • Pediatric Urology and Nephrology Studies
  • Kidney Stones and Urolithiasis Treatments
  • Orthopedic Infections and Treatments
  • Vascular Malformations Diagnosis and Treatment
  • Acute Kidney Injury Research
  • Cardiac and Coronary Surgery Techniques
  • Glioma Diagnosis and Treatment
  • Pituitary Gland Disorders and Treatments
  • Cardiac tumors and thrombi
  • Ureteral procedures and complications
  • Reconstructive Surgery and Microvascular Techniques
  • Pancreatic and Hepatic Oncology Research
  • Radiomics and Machine Learning in Medical Imaging
  • Knee injuries and reconstruction techniques
  • Endometrial and Cervical Cancer Treatments
  • Hydrogels: synthesis, properties, applications

Army Medical University
2021-2024

Southwest Hospital
2021-2024

Chongqing Medical University
2020-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2024

Children's Hospital of Chongqing Medical University
2020-2024

Fudan University
2021-2022

Shanghai Institute of Hematology
2021

Second Hospital of Anhui Medical University
2020-2021

Anhui Medical University
2020-2021

Peking Union Medical College Hospital
2018-2021

The direct binding mechanism for urea-based denaturation of proteins was tested with a thermoresponsive polymer, poly(N-isopropylacrylamide) (PNIPAM). Thermodynamic measurements the polymer's hydrophobic collapse were complemented by Fourier transform infrared (FTIR) spectroscopy, Stokes radius measurements, and methylated urea experiments. It found that lower critical solution temperature (LCST) PNIPAM decreased as added to solution. Therefore, actually facilitated macromolecule. Moreover,...

10.1021/ja9016057 article EN Journal of the American Chemical Society 2009-06-15

Gastrointestinal stromal tumors (GISTs), the most common mesenchymal of digestive tract with potential for malignant transformation, are mainly treated by open surgery or laparoscopic resection. The aim this retrospective study was to evaluate clinical efficacy, safety, and feasibility endoscopic submucosal dissection (ESD) large-size (2-5 cm) GISTs in esophagus stomach.A total 31 patients (6 patients) stomach (25 underwent ESD between September 2008 December 2011. Demographics, data,...

10.1111/jgh.12056 article EN Journal of Gastroenterology and Hepatology 2012-11-29

To evaluate and compare the outcomes of utilizing patient-specific instrumentation (PSI) technology, which incorporates personalized three-dimensional (3D) preoperative planning customized 3D printing (3DP) osteotomy guides, against those achieved with traditional instruments in total elbow arthroplasty (TEA). A retrospective study was conducted to analyze clinical data 20 patients diagnosed arthritis who underwent TEA at Center for Joint Surgery, The First Hospital Affiliated Army Medical...

10.1186/s12893-025-02864-2 article EN cc-by-nc-nd BMC Surgery 2025-04-04

The purpose of this study was to investigate the role CT radiomics features combined with a support vector machine (SVM) model in potentially differentiating pelvic rhabdomyosarcoma (RMS) from yolk sac tumors (YSTs) children.A total 94 patients RMS (n = 49) and YSTs 45) were enrolled. Non-enhanced phase (NP), arterial (AP), venous (VP) images retrieved for analysis. volumes interest (VOIs) constructed by segmenting tumor regions on extract features. Datasets randomly divided into two sets...

10.3389/fonc.2020.584272 article EN cc-by Frontiers in Oncology 2020-11-24

Emergent and late conversions form OFF-to-ON pump coronary artery bypass grafting (CABG) have been associated with worse outcomes, however, it remains unclear as to which risk factors are conversion how prevent them.Among 4718 patients who randomly underwent off- or on-pump CABG, the incidence of off-pump cross-over, 'OFF-to-ON conversion', was 7.9% (186/2356). The primary outcome a composite death, stroke, myocardial infarction, new renal failure requiring dialysis. We assessed outcomes...

10.1093/ejcts/ezw361 article EN European Journal of Cardio-Thoracic Surgery 2016-10-18

Abstract A review was undertaken of the operation process and development transcutaneous electrical acupoint stimulation (TEAS) related devices for TEAS, with aim to offer a reference developing an international standard basic safety essential performance devices. The articles TEAS instruction were searched using EMBASE, MEDLINE, Web Science databases time period from inception July 18, 2023. In absence parameter description stimulators, multimeter used measure output voltage, resistance,...

10.1097/st9.0000000000000034 article EN cc-by-nc-nd Science of Traditional Chinese Medicine 2024-06-01

Pituitary adenomas are among the most common primary intracranial tumours. They predominantly benign and account for 10–15 % of all neoplasms. These tumours divided into two subgroups: macroadenomas (> 1 cm) microadenomas (<1 cm). About 30% pituitary do not produce hormones. In other cases can any hormones anterior gland thus cause endocrine disorders. Compression gland, adjacent cranial nerves brain structures lead to failure, nerve deficit neurological Visual impairment, usually with...

10.24060/2076-3093-2019-9-4-311-316 article EN cc-by Creative Surgery and Oncology 2020-01-24

Background: Acute kidney injury (AKI) is a common complication after cardiac surgery and the prognosis of AKI worsens with increase in severity. Syndecan-1(SDC-1) biomarker endothelial glycocalyx degradation. Fluid overload (FO) associated poor outcomes patients may be related to damage function. This study aimed at demonstrating association between elevated SDC-1, FO, progression. Methods: In this prospective study, we screened who underwent enrolled experienced an within 48 h from December...

10.3389/fmed.2021.648397 article EN cc-by Frontiers in Medicine 2021-07-30

Postmediastinal schwannoma is a kind of neurogenic tumor originating from the neuron sheath in posterior mediastinum. In majority cases these tumors are located paravertebral sulcus and incidence similar both sides thorax as single or multiple; however, multi-schwannomas involved bilateral postmediastinum rare. We report case postmediastinal discuss clinical surgical treatment. aware no previously published reports on this rare condition.

10.1111/j.1759-7714.2010.00022.x article EN other-oa Thoracic Cancer 2010-07-07

Abstract Background The purpose of this study was to compare the accuracy new HURWA robotic‐assisted total knee arthroplasty (TKA) technique conventional in a sawbone model. Methods TKA system applied robotic group. After bone resection, all these sawbones were scanned by use structured light scanning system. Measurements resections, femoral coronal and sagittal measurements, tibial measurements recorded. Results Compared technique, significantly improved resection levels angles. In group,...

10.1002/rcs.2263 article EN International Journal of Medical Robotics and Computer Assisted Surgery 2021-04-10

Pre-existing renal dysfunction is an independent risk factor for cardiac surgery-associated acute kidney injury (AKI). We aimed to investigate whether the improvement of postoperative function after coronary artery bypass grafting (CABG) surgery would affect AKI in patients with different levels baseline function.Data were collected from who underwent CABG January 2018 April 2019. Patients divided into normal (GFR ≥ 90 ml/min/1.73 m2 ), non-CKD (60≤GFR < and CKD 60 ) groups. Improvement was...

10.1002/clc.23785 article EN Clinical Cardiology 2022-01-30

BACKGROUND Research on microparticles is rapidly evolving and has extended to the field of many diseases. It unclear whether can be stored frozen. In this study, our goal was verify cryopreservation had an effect properties microparticles. MATERIAL AND METHODS We obtained C57BL/6J mouse-derived by grinding gradient centrifugation. The specimens were divided into 2 groups: without dimethyl sulfoxide with sulfoxide. then at 25°C, 4°C, -20°C, -80°C, -196°C for 0.5 days, 1 day, 3 5 7 days....

10.12659/msm.917962 article EN Medical Science Monitor 2019-09-06

Abstract Rationale: Pediatric pancreatic teratoma (PPT) is a rare tumor with unclear clinicopathologic features and treatment strategy. Patient concerns: A 13-month-old boy was admitted to the hospital complaint of palpable epigastric mass. Diagnoses: The lesion diagnosed as benign mature cyst via postoperative pathological examination. Interventions: Pylorus-preserving pancreaticoduodenectomy (PPPD) performed on patient. entire mass resected from head pancreas sent laboratory for frozen...

10.1097/md.0000000000018001 article EN cc-by-nc Medicine 2019-11-01

Objective: The objective of this study was to compare the perioperative, oncological, and functional results complications extracorporeal orthotopic neobladder (EON) totally intracorporeal (ION) after laparoscopic radical cystectomy (LRC) in patients with muscle-invasive bladder cancer high-risk nonmuscle-invasive cancer. Methods: From January 2013 October 2019, 152 underwent LRC U-shape urinary diversion at a single tertiary referral hospital. We then compared (n = 62) 90) groups. Results:...

10.1089/lap.2021.0519 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2021-09-17

10.1016/j.jacc.2013.03.091 article EN publisher-specific-oa Journal of the American College of Cardiology 2013-07-17

Most of recurrent bladder carcinoma after partial cystectomy did not cause diagnostic difficulties for urologists, because the appearance typical papillary in ultrasonography or cystoscopy, and could be easily confirmed by tumor biopsy. Three patients, ages from 35 to 62 years, had undergone sparing treatment muscle invasive cancer, all them biopsy revealed benign lesion at surveillance cystoscopy. However, transurethral resection showed high-grade urothelial these patients. Two patients...

10.1097/md.0000000000000898 article EN cc-by-nc Medicine 2015-06-01

Objective To evaluate the effectiveness and safety of sacral neuromodulation for treatment painful bladder syndrome/interstitial cystitis. Methods There were 21 cystitis patients treated during April 2012 to October 2014. Behavior therapy, oral intravesical instillation sterile sodium hyaluronate, water expansion bladder, submucosal injection botulinum toxin type A so on did not have a good effect patients. The data voiding diary, visual pain scale, interstitial symptom index quality...

10.3760/cma.j.issn.1000-6702.2015.02.004 article EN Zhonghua miniao waike zazhi 2015-02-15
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