A5080287457- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Venous Thromboembolism Diagnosis and Management
- Genetic Neurodegenerative Diseases
- COVID-19 Clinical Research Studies
- Psychosomatic Disorders and Their Treatments
- COVID-19 and healthcare impacts
- Diet and metabolism studies
- Muscle Physiology and Disorders
- Mitochondrial Function and Pathology
- Body Image and Dysmorphia Studies
- COVID-19 and Mental Health
- Gambling Behavior and Treatments
- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Reading and Literacy Development
- Schizophrenia research and treatment
- Personality Disorders and Psychopathology
- Atrial Fibrillation Management and Outcomes
- Chronic Myeloid Leukemia Treatments
- Oropharyngeal Anatomy and Pathologies
- Inflammasome and immune disorders
- Migraine and Headache Studies
- Digital Mental Health Interventions
- Inflammatory Biomarkers in Disease Prognosis
Sapienza University of Rome
1988-2024
Aziende Socio Sanitarie Territoriale Ovest Milanese
2020-2022
Neuroscience Institute
2020-2022
Paradise Valley Hospital
2021
Ospedale Maggiore
2021
University of Insubria
2016-2017
Università Cattolica del Sacro Cuore
1995-2015
University of Chieti-Pescara
2000
University of Padua
1976-1999
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) and Autoimmune Disorder Associated with Streptococcal Infections (PANDAS) are conditions that impair brain normal neurologic function, resulting in the sudden onset of tics, obsessive compulsive disorder, other behavioral symptoms. Recent studies have emphasized crosstalk between gut brain, highlighting how composition can influence behavior functions. Thus, present study investigates relationship PANS/PANDAS microbiota ecology. The a...
Abstract Gilles de la Tourette syndrome is a multifaceted neurodevelopmental disorder characterized by multiple motor and vocal tics. Research in has traditionally focused on the system. However, there increasing evidence that perceptual cognitive processes play crucial role as well. Against this background it been reasoned linking perception action might be particularly affected these patients with strength of perception-action binding being increased. not yet studied experimentally. Here,...
During the early stages of coronavirus disease 2019 (COVID-19) pandemic in Italy, an online survey was launched via a local patient advocacy website to investigate mental health issues children and adolescents with Tourette syndrome (TS). Respondents were parents, who asked report on their child's general health, tics, comorbidities/problems, pharmacological treatment/psychotherapy, symptom variations, daily routine, as well family's work experiences during pandemic. Two hundred thirty-eight...
Background: Cognitive functions represent foundational factors for mental health and quality of life (QoL). In Tourette syndrome (TS), psychiatric comorbidities are common have been inconsistently reported to affect the cognition QoL patients, while role tic disorder duration has not yet explored. Methods: To examine how TS may influence QoL, N = 80 children with (6–16 years) were evaluated using Wechsler Intelligence Scale Children (WISC-IV). Standardized questionnaires used assess presence...
Abstract Tourette syndrome (TS) and obsessive–compulsive disorder (OCD) are two neurodevelopmental disorders characterized by repetitive behaviors. Our recent study in drug-naive children with TS OCD provided evidence of cerebellar involvement both disorders. In addition, functional connectivity (FC) was similar patients without comorbidities (TSpure) comorbidity (TS + OCD), but differed pure patients. To investigate detail the pathophysiology OCD, we explored structural abnormalities...
Because tics are the defining clinical feature of Tourette syndrome, it is conceptualized predominantly as a motor disorder. There some evidence though suggesting that neural basis syndrome related to perception-action processing and binding between perception action. However, processes have not been examined in domain these patients. If particularly but within system, this would further corroborate predominantly, or solely, Here, we studied N = 22 patients 24 healthy controls using an...
Venous thromboembolism is a frequent complication of COVID-19 infection. Less than 50% pulmonary embolism (PE) associated with the evidence deep venous thrombosis (DVT) lower extremities. DVT may also occur in system upper limbs especially if provoking conditions are present such as continuous positive airway pressure (CPAP). The aim this study was to evaluate incidence UEDVT patients affected by moderate-severe infection and identify potential risk factors for its occurrence.We performed...
Morphological changes in the oesophageal epithelium of Oreochromis mossambicus, O. niloticus , and mossambicus x hybrids were studied during adaptation to sea water. In fresh water, is stratified rich with mucous cells. salt modifications occur oesophagus hybrid: mucosa folds are more vascularized covered a monolayered epithelium, alternating multilayered one. The does not seem be affected by salinity but this species survives only for brief periods These observations underline close...
Misophonia is a condition characterized by the dislike or hatred (miso) of specific sounds (phonia) that results in an extreme emotional response. There has been growing interest misophonia, with emerging evidence from neurodevelopmental populations and ongoing debate regarding psychiatric classification mechanisms underlying this phenomenon. This first article to report on misophonic experiences associated clinical characteristics young people tic disorders.In article, we present cases 12...
The COVID-19 pandemic has deeply affected the psychophysical wellbeing of children worldwide. Alexithymia, a personality trait involving difficulties in identifying and expressing feelings represents vulnerability factor for stress-related disorders. Under stress exposure, we aimed to investigate role parents’ children’s alexithymia symptomatology shown by evaluate possible differences according age, gender history infections. perception parents about impact on emotional, social...
Abstract Despite intense and costly treatments, developmental dyslexia (DD) often persists into adulthood. Several brain skills unrelated to speech sound processing (i.e., phonology), including the spatial distribution of visual attention, are abnormal in DD may represent possible treatment targets. This study explores efficacy rightward prismatic adaptation (rPA), a visuomotor technique that enables visuo-attentive recalibration through shifts field induced by goggles. A digital...
Tourette syndrome (TS) and early-onset obsessive-compulsive disorder (OCD) are frequently associated conceptualized as distinct phenotypes of a common disease spectrum. However, the nature their relationship is still largely unknown on pathophysiological level. In this study, early structural white matter (WM) changes investigated through diffusion tensor imaging (DTI) were compared across four groups drug-naïve children: TS-pure (n = 16), TS+OCD 14), OCD 10), 11 age-matched controls. We...
ABSTRACT The celibacy and fertility rates of 186 patients with major affective disorders were analysed as a function the presence or absence histories mood congruent delusions suicidal behaviour in depressive phases disease. Both delusional irrelevant to rates. On contrary, depressives had reduced incidence cases 2 more children suicide attempters both lower frequency high‐fertility smaller mean number than nonattempters. differences apparently not attributable length fertile period life...