A5078611655- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Food Safety and Hygiene
- Molecular Junctions and Nanostructures
- Electrochemical Analysis and Applications
- Epigenetics and DNA Methylation
- Quality and Supply Management
- Conducting polymers and applications
- Escherichia coli research studies
- Graphene and Nanomaterials Applications
- Biosensors and Analytical Detection
- Reproductive System and Pregnancy
- Neuroscience and Neural Engineering
- Biochemical Analysis and Sensing Techniques
- Nanowire Synthesis and Applications
- Advanced Fluorescence Microscopy Techniques
- Facial Rejuvenation and Surgery Techniques
- Demographic Trends and Gender Preferences
- Anatomy and Medical Technology
- Physiological and biochemical adaptations
- Adrenal Hormones and Disorders
- Digital Imaging in Medicine
- Soil Management and Crop Yield
- Thyroid Disorders and Treatments
University College Cork
2021-2025
Swansea University
2012-2020
International Iberian Nanotechnology Laboratory
2020
Universidade do Porto
2011-2012
European Molecular Biology Laboratory
2007
European Science Foundation
2007
Keele University
2007
European Synchrotron Radiation Facility
2007
Human chorionic gonadotropin (hCG) is a key diagnostic marker of pregnancy and an important biomarker for cancers in the prostate, ovaries bladder therefore great importance diagnosis. For this purpose, new immunosensor screen-printed electrodes (SPEs) presented here. The device was fabricated by introducing polyaniline (PANI) conductive layer, via situ electropolymerization aniline, onto graphene support. PANI-coated acts as working electrode three terminal electrochemical sensor....
Parental effects influence offspring phenotypes through pre- and post-natal routes but little is known about their molecular basis, therefore adaptive significance. Epigenetic modifications, which control gene expression without changes in the DNA sequence are influenced by environment, may contribute to parental effects. We investigated of environmental enrichment on behaviour, metabolic rate brain methylation patterns parents highly inbreed mangrove killifish (Kryptolebias marmoratus)....
Shiga toxin-producing E. coli (STEC) is a food-borne pathogen of significant public health concern, due to the severity illness it can cause at low infection dose. The key targets in molecular-based assays detect STEC are stx1 or stx2 genes, coding for ability produce T Toxin 1 and 2, respectively. most commonly used molecular detection techniques, such as PCR real-time PCR, considerably time-consuming there an urgent need more rapid screening assay which could be agri-food settings. In this...
This study aims to develop and validate a novel fast-detection electrochemical sensing platform enhance portable sensor solutions. The research focuses on optimising analogue front-end circuits, developing data analysis algorithms, validating the device through experiments measurement accuracy detection speed, enabling on-site measurements across diverse applications. work successfully designed Portable Unit for Lab-on-Site Electrochemistry (PULSE) system with dimensions of (78×100×2) mm3....
Abstract With current diagnostic methods detection of stage 1 or 2 ovarian cancer using CA125 is possible in only 75% cases. The ability to detect at lower concentrations could significantly improve such early diagnosis. Here, the use screen‐printed graphene biosensors as a label‐free platform for was evaluated. sensor fabricated through deposition polyaniline layer via electropolymerisation on electrode. surface functionalised with anti‐CA125 antibody covalent cross linking polyaniline....
The worldwide implementation and certification of food safety management systems (FSMS) have increased significantly during the last few years, thus reflecting importance assuming these standards in some activity sectors. Based on literature review carried out, there are a large number research projects that been conducted this area. However, as far Portugal is concerned, nationwide related to ISO 22000 scarce. Therefore, paper reflects what we believe be pioneering contribution order study...
Abstract A new immunosensor is presented for human chorionic gonadotropin (hCG), made by electrodepositing chitosan/gold‐nanoparticles over graphene screen‐printed electrode (SPE). The antibody was covalently bound to CS via its Fc‐terminal. assembly controlled electrochemical Impedance Spectroscopy (EIS) and followed Fourier Transformed Infrared (FTIR). hCG‐immunosensor displayed linear response against the logarithm‐hCG concentration 0.1–25 ng/mL with limit of detection 0.016 ng/mL. High...
Hybrid diamond–graphite nanoplatelet (DGNP) thin films are produced and applied to label-free impedimetric biosensors for the first time, using avidin detection as a proof of concept. The DGNPs synthesized by microwave plasma chemical vapor deposition through H2/CH4/N2 gas mixtures in reproducible rapid single-step process. material building unit consists an inner two-dimensional-like nanodiamond with preferential vertical alignment covered covalently bound nanocrystalline graphite grains,...
Silver is widely used on screen-printed electrodes (SPEs) to provide a reference potential for electrochemical measurements such as impedance spectroscopy (EIS). The redox activity between silver and electrolyte in SPE-based experiments rarely reported detail, despite the critical reliance of potentiometric measurement accuracy predictability reactions at electrodes. In this work, potassium ferrous cyanides typically components were shown adsorb surface when applied SPEs. EIS was performed...
Cortisol is a well established biomarker hormone that regulates many processes in the body and widely referred to as stress hormone. can be used marker allow for detection of levels dogs during training process. This test will indicate if they handle under or might more suitable an assistant companion dog. An immunosensor cortisol was developed using electrochemical impedance spectroscopy (EIS). The sensor characterized chemical topographical techniques. calibrated its sensitivity determined...
Microneedles (MN) are short, sharp structures that have the ability to painlessly pierce stratum corneum, outermost layer of skin, and interface with dermal interstitial fluid lies beneath. Because is rich in biomarkers, microneedle-based biosensors potential be used a wide range diagnostic applications. To act as an electrochemical sensor, tip or body MN must functionalized, while substrate areas generally passivated block any unwanted background interference may occur outside skin. This...
Electrochemical immunosensor devices comprise of an antibody immobilised onto a semiconducting or conducting substrate. The use epitaxial graphene in immunosensors allows for the detection antigen specifically bound to by monitoring current modulation lithographically fabricated channel devices. Multilayer (MEG) was produced on semi-insulating 4H-SiC(0001) substrates annealing at 1700°C 1x 10 -5 mbar using graphite cap. Thickness and morphology studied Raman spectroscopy, XPS, AFM, SEM....