- Functional Brain Connectivity Studies
- Bipolar Disorder and Treatment
- LGBTQ Health, Identity, and Policy
- Autism Spectrum Disorder Research
- Advanced Neuroimaging Techniques and Applications
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Obsessive-Compulsive Spectrum Disorders
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Child Abuse and Trauma
- African Sexualities and LGBTQ+ Issues
- Neural dynamics and brain function
- Reproductive Health and Technologies
- Suicide and Self-Harm Studies
- Behavioral Health and Interventions
- Fetal and Pediatric Neurological Disorders
- Neurological disorders and treatments
- Attention Deficit Hyperactivity Disorder
- Medical Image Segmentation Techniques
- Sex and Gender in Healthcare
- Evolutionary Psychology and Human Behavior
- Treatment of Major Depression
- Psychosomatic Disorders and Their Treatments
- Morphological variations and asymmetry
University of Massachusetts Chan Medical School
2023-2024
Yale University
2008-2022
University of Pittsburgh
2018-2022
China Medical University
2017-2020
First Hospital of China Medical University
2017-2020
University of Pittsburgh Medical Center
2017-2020
Institute of Psychology, Chinese Academy of Sciences
2019
Washington University in St. Louis
2019
University of California, Berkeley
2019
Northwestern University
2019
Transgender healthcare is a rapidly evolving interdisciplinary field. In the last decade, there has been an unprecedented increase in number and visibility of transgender gender diverse (TGD) people seeking support gender-affirming medical treatment parallel with significant rise scientific literature this area. The World Professional Association for Health (WPATH) international, multidisciplinary, professional association whose mission to promote evidence-based care, education, research,...
Objective: To study the relationship between selfreported exposure to childhood maltreatment (CM) and cerebral gray matter (GM) morphology in adolescents without psychiatric diagnoses.Design: Associations were examined regional GM CM (measured using a trauma self-report questionnaire for physical, emotional, sexual abuse physical emotional neglect).Setting: University hospital.Participants: Forty-two diagnoses.Main Outcome Measures: Correlations scores volume assessed voxel-based analyses of...
Brain network alterations have increasingly been implicated in schizophrenia (SCZ), bipolar disorder (BD), and major depressive (MDD). However, little is known about the similarities differences functional brain networks among patients with SCZ, BD, MDD. A total of 512 participants (121 100 108 MDD, 183 healthy controls, matched for age sex) completed resting-state magnetic resonance imaging at a single site. Four global measures (the clustering coefficient, characteristic shortest path...
Background: Schizophrenia (SZ), bipolar disorder (BD), and major depressive (MDD) are distinct diagnostic categories in current psychiatric nosology, yet there is increasing evidence for shared clinical biological features these disorders. No previous studies have examined brain structural concurrently 3 The aim of this study was to identify the extent alterations SZ, BD, MDD. We gray matter (GM) volume white (WM) integrity a total 485 individuals (135 with 86 108 MDD, 156 healthy controls...
Finding neural features of suicide attempts (SA) in major depressive disorder (MDD) may be helpful preventing suicidal behavior. The ventral and medial prefrontal cortex (PFC), as well the amygdala form a circuit implicated emotion regulation pathogenesis MDD. aim this study was to identify whether patients with MDD who had history SA show structural functional connectivity abnormalities PFC relative without SA. We measured gray matter volume amygdala-PFC using magnetic resonance imaging...
Previous cross-sectional study of ventral prefrontal cortex (VPFC) implicated progressive volume abnormalities during adolescence in bipolar disorder (BD). In the present study, a within-subject, longitudinal design was implemented to examine brain changes adolescence/young adulthood. We hypothesized that VPFC decreases over time would be greater adolescents/young adults with BD than healthy comparison adults. Eighteen (10 I and 8 participants) underwent two high-resolution magnetic...
Anxiety and depression co-occur; the neural substrates of shared unique components these symptoms are not understood. Given emotional alterations in internalizing disorders, we hypothesized that function regions associated with emotion processing/regulation, including anterior cingulate cortex (ACC), amygdala fusiform gyrus (FG), would differentiate symptoms. Forty-three adults completed an functional magnetic resonance imaging task Hamilton Depression Scales. We transformed scales to...
The olfactocentric paralimbic cortex plays a critical role in the regulation of emotional and neurovegetative functions that are disrupted core features bipolar disorder. Adolescence is thought to be period both maturation emergence disorder pathology. Together, these factors implicate central for development suggest abnormalities this may expressed by adolescence We tested hypothesis differences structure morphological feature adolescents with Subjects included 118 (41 77 healthy controls)....
Emotionally arousing pictures induce increased activation of visual pathways relative to emotionally neutral images. A predominant model for the preferential processing and attention emotional stimuli posits that amygdala modulates sensory through its projections cortices. However, recent behavioral studies have found intact perceptual facilitation in individuals with damage. To determine importance modulations processing, we used functional magnetic resonance imaging examine cortical blood...
Children with autism spectrum disorder (ASD) show impairment in reciprocal social communication, which includes deficits cognition and behavior. Since behavior are considered to be interdependent, it is valuable examine processes on multiple levels of analysis. Neuropsychological measures face processing often reveal ASD including the ability identify remember facial information. However, extent neuropsychological associated or predictive real-world unclear.The study investigated 66 children...
<h3>Background:</h3> Growing evidence indicates both shared and distinct features of emotional perception in schizophrenia, bipolar disorder major depressive disorder. In these disorders, alterations spontaneous low-frequency fluctuations have been reported the neural system for perception, but similarities differences amplitude fluctuation (ALFF) across 3 disorders are unknown. <h3>Methods:</h3> We compared ALFF its signal balance at 2 frequency bands (slow-5 slow-4) 119 participants with...